Details of the Drug Pharmacogenomic Perturbation Atlas

General Information of Drug (ID: DM69G8X)

• Drug Name: L-glutamine Drug Info
• Synonyms: NutreStore; AES-14; Aesgen-14; Glutamine (INN); L-glutamine (oral, short bowel syndrome), Emmaus; L-glutamine (topical, chemotherapy-induced mucositis), Aesgen; L-glutamine (oral, sickle cell anemia/sickle beta-0 thalassemia), Emmaus; L-glutamine (oral, sickle cell anemia/sickle beta-0 thalassemia), Emmaus/University of California Los Angeles
• Cross-matching ID:
  PubChem CID: 5961
  ChEBI ID: CHEMBL18050
  CAS Number: CAS 56-85-9
  TTD Drug ID: D01JIA
  VARIDT Drug ID: DR00024

Consensus Signature of Drug Pharmacogenomic Perturbation (DPP)

Term Name	NES	FDR q-val	Tag %	Leading Edge Genes
Antigen processing and presentation	-1.77	4.90e-2	60/78 (76.92%)	HSPA1A;CIITA;HLA-DPA1;...
Intestinal immune network for IgA production	-2.03	0.00e+0	38/48 (79.17%)	IL15RA;HLA-DOB;HLA-DRB1;...

Pharmacogenomic Perturbation Across Diseases and Tissues

Breast

Breast adenocarcinoma

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
MCF7	CVCL_0031	Homo sapiens	0.002uM - 10uM	6H, 24H	Hide ▲

Lung

Lung adenocarcinoma

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
A549	CVCL_0023	Homo sapiens	0.002uM - 10uM	6H	Hide ▲

Non-small cell lung carcinoma

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
HCC515	CVCL_5134	Homo sapiens	0.002uM - 10uM	6H	Show ▼

Prostate

Prostate carcinoma

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
PC-3	CVCL_0035	Homo sapiens	0.002uM - 10uM	6H, 24H	Show ▼