| Oxidative phosphorylation |
1.88 |
5.61e-2 |
93/133 (69.92%) |
ATP5PF;NDUFB1;NDUFA1;...
|
| Ferroptosis |
1.80 |
8.82e-2 |
36/41 (87.8%) |
ACSL1;STEAP3;GCLM;...
|
| Non-alcoholic fatty liver disease |
1.76 |
8.82e-2 |
126/155 (81.29%) |
CASP8;INSR;CYCS;...
|
| Diabetic cardiomyopathy |
1.74 |
7.62e-2 |
162/203 (79.8%) |
AGT;SLC25A6;INSR;...
|
| Staphylococcus aureus infection |
1.68 |
9.94e-2 |
72/95 (75.79%) |
FGG;C3;KRT19;...
|
| Thermogenesis |
1.60 |
1.94e-1 |
173/232 (74.57%) |
ACSL1;ATP5PF;NDUFB1;...
|
| Fatty acid biosynthesis |
1.59 |
1.74e-1 |
16/18 (88.89%) |
ACSL1;ACSL5;ACACA;...
|
| Glycolysis / Gluconeogenesis |
1.52 |
2.69e-1 |
56/67 (83.58%) |
GPI;ALDH1B1;PGM1;...
|
| p53 signaling pathway |
1.52 |
2.41e-1 |
63/73 (86.3%) |
CASP8;SESN1;PERP;...
|
| Aminoacyl-tRNA biosynthesis |
1.47 |
3.16e-1 |
15/66 (22.73%) |
CARS2;GATC;LARS2;...
|
| Ribosome |
1.47 |
2.99e-1 |
113/158 (71.52%) |
MRPL33;RPS5;RPL36AL;...
|
| Pentose phosphate pathway |
1.45 |
2.98e-1 |
25/30 (83.33%) |
GPI;PRPS2;PGM1;...
|
| Glutathione metabolism |
1.45 |
2.84e-1 |
43/57 (75.44%) |
GCLM;RRM2;LAP3;...
|
| Alzheimer disease |
1.42 |
3.22e-1 |
279/369 (75.61%) |
CASP8;CTNNB1;SLC25A6;...
|
| Complement and coagulation cascades |
1.41 |
3.23e-1 |
76/85 (89.41%) |
FGG;SERPINA1;C3;...
|
| Histidine metabolism |
1.39 |
3.52e-1 |
16/22 (72.73%) |
MAOA;ALDH1B1;ALDH9A1;...
|
| Coronavirus disease |
1.38 |
3.44e-1 |
215/232 (92.67%) |
FGG;C3;F13A1;...
|
| Primary bile acid biosynthesis |
1.37 |
3.59e-1 |
15/17 (88.24%) |
ACOX2;AMACR;HSD17B4
|
| Parkinson disease |
1.37 |
3.57e-1 |
176/249 (70.68%) |
MAOA;SLC25A6;NFE2L2;...
|
| Central carbon metabolism in cancer |
1.36 |
3.58e-1 |
67/70 (95.71%) |
LDHB;PDHB;PIK3R1;...
|
| Phenylalanine metabolism |
1.36 |
3.44e-1 |
14/17 (82.35%) |
MAOA;GOT2;ALDH3A1;...
|
| Neutrophil extracellular trap formation |
1.34 |
3.64e-1 |
101/189 (53.44%) |
FGG;C3;FGB;...
|
| Peroxisome |
1.34 |
3.50e-1 |
72/82 (87.8%) |
ACSL1;ACOX2;PEX6;...
|
| Phosphonate and phosphinate metabolism |
1.34 |
3.41e-1 |
5/6 (83.33%) |
PCYT1A;CHPT1;CEPT1
|
| Caffeine metabolism |
1.34 |
3.35e-1 |
5/6 (83.33%) |
NAT1;CYP2A6
|
| Arginine and proline metabolism |
1.33 |
3.44e-1 |
39/50 (78%) |
P4HA1;MAOA;GOT2;...
|
| Huntington disease |
1.33 |
3.36e-1 |
233/306 (76.14%) |
CASP8;STX1A;TGM2;...
|
| Pyruvate metabolism |
1.32 |
3.36e-1 |
41/47 (87.23%) |
ALDH1B1;LDHB;ALDH9A1;...
|
| Estrogen signaling pathway |
1.31 |
3.47e-1 |
119/137 (86.86%) |
KRT19;KRT23;KRT13;...
|
| Ubiquinone and other terpenoid-quinone biosynthesis |
1.31 |
3.40e-1 |
9/11 (81.82%) |
COQ2;HPD;NQO1;...
|
| Toxoplasmosis |
-1.35 |
3.75e-1 |
103/112 (91.96%) |
HSPA6;HLA-DOB;BAD;...
|
| Cytokine-cytokine receptor interaction |
-1.37 |
3.43e-1 |
246/295 (83.39%) |
INHBE;IL15;IL36RN;...
|
| Tight junction |
-1.37 |
3.51e-1 |
130/169 (76.92%) |
NF2;TJP3;PARD3;...
|
| Retinol metabolism |
-1.38 |
3.41e-1 |
41/68 (60.29%) |
RDH16;RDH5;DHRS9;...
|
| Bladder cancer |
-1.38 |
3.37e-1 |
40/41 (97.56%) |
DAPK3;E2F3;MAPK1;...
|
| Apelin signaling pathway |
-1.39 |
3.46e-1 |
117/137 (85.4%) |
ADCY9;CALML3;PRKAB1;...
|
| Pancreatic cancer |
-1.39 |
3.52e-1 |
75/76 (98.68%) |
BAD;ARHGEF6;BAX;...
|
| Steroid hormone biosynthesis |
-1.39 |
3.62e-1 |
43/61 (70.49%) |
HSD17B1;CYP17A1;CYP21A2;...
|
| Kaposi sarcoma-associated herpesvirus infection |
-1.40 |
3.66e-1 |
172/193 (89.12%) |
BAX;BAK1;HLA-E;...
|
| Signaling pathways regulating pluripotency of stem cell... |
-1.41 |
3.48e-1 |
110/143 (76.92%) |
DVL2;MYF5;INHBE;...
|
| C-type lectin receptor signaling pathway |
-1.41 |
3.61e-1 |
93/104 (89.42%) |
IRF9;BCL3;ITPR3;...
|
| Mineral absorption |
-1.42 |
3.60e-1 |
48/60 (80%) |
ATP2B4;FTL;SLC39A4;...
|
| Phototransduction |
-1.44 |
3.17e-1 |
21/29 (72.41%) |
GNGT1;GUCA1B;GNAT1;...
|
| TNF signaling pathway |
-1.46 |
2.96e-1 |
103/112 (91.96%) |
IL15;BCL3;NFKBIA;...
|
| Osteoclast differentiation |
-1.46 |
3.03e-1 |
117/127 (92.13%) |
LILRB5;BLNK;NFATC1;...
|
| Primary immunodeficiency |
-1.47 |
2.99e-1 |
33/38 (86.84%) |
ZAP70;BLNK;ICOS;...
|
| Th1 and Th2 cell differentiation |
-1.48 |
3.13e-1 |
80/92 (86.96%) |
NFATC1;HLA-DOB;HLA-DPB1;...
|
| Renin secretion |
-1.49 |
2.98e-1 |
61/69 (88.41%) |
ITPR2;PDE1A;PDE3A;...
|
| Melanoma |
-1.51 |
2.77e-1 |
68/72 (94.44%) |
BAD;BAX;BAK1;...
|
| TGF-beta signaling pathway |
-1.52 |
2.76e-1 |
81/94 (86.17%) |
ACVR1;PPP2CB;TGFB3;...
|
| AGE-RAGE signaling pathway in diabetic complications |
-1.52 |
2.96e-1 |
97/100 (97%) |
BAX;TGFB3;AGTR1;...
|
| Cell adhesion molecules |
-1.52 |
3.19e-1 |
118/148 (79.73%) |
HLA-E;ICOS;CLDN9;...
|
| Hematopoietic cell lineage |
-1.53 |
3.47e-1 |
90/99 (90.91%) |
HLA-DPB1;EPOR;CD9;...
|
| Malaria |
-1.54 |
3.39e-1 |
44/50 (88%) |
KLRB1;TGFB3;HGF;...
|
| Rheumatoid arthritis |
-1.56 |
3.62e-1 |
78/93 (83.87%) |
HLA-DOB;TGFB3;HLA-DPB1;...
|
| African trypanosomiasis |
-1.60 |
2.97e-1 |
32/37 (86.49%) |
IFNG;IL1B;TNF;...
|
| Gastric acid secretion |
-1.63 |
2.80e-1 |
63/76 (82.89%) |
ATP1B1;KCNJ15;ATP1B2;...
|
| Epithelial cell signaling in Helicobacter pylori infect... |
-1.63 |
3.46e-1 |
62/70 (88.57%) |
NFKBIA;CXCL8;NOD1;...
|
| Proximal tubule bicarbonate reclamation |
-1.80 |
8.84e-2 |
21/23 (91.3%) |
AQP1;ATP1B3;GLS;...
|
| Pentose and glucuronate interconversions |
-1.85 |
7.07e-2 |
17/34 (50%) |
UGT2B17;UGT2B15;UGT2A3;...
|
