Details of the Drug Pharmacogenomic Perturbation Atlas

General Information of Drug (ID: DM6Y3A0)

Drug Name
GALLICACID Drug Info
Synonyms
Gallic acid; 3,4,5-Trihydroxybenzoic acid; 149-91-7; gallate; Benzoic acid, 3,4,5-trihydroxy-; Gallic acid, tech.; GALOP; Pyrogallol-5-carboxylic acid; Kyselina gallova; HSDB 2117; 3,4,5-Trihydroxybenzoate; CCRIS 5523; Kyselina gallova [Czech]; Gallic acid polymer; UNII-632XD903SP; NSC 674319; Gallicum acidum; CHEBI:30778; AI3-16412; Kyselina 3,4,5-trihydroxybenzoova; EINECS 205-749-9; NSC 20103; BRN 2050274; GALLIC ACID ANHYDROUS; Kyselina 3,4,5-trihydroxybenzoova [Czech]; CHEMBL288114; LNTHITQWFMADLM-UHFFFAOYSA-N; 632XD903SP
Cross-matching ID
PubChem CID
370
ChEBI ID
CHEMBL288114
CAS Number
CAS 149-91-7
TTD Drug ID
D0Y3TZ

Consensus Signature of Drug Pharmacogenomic Perturbation (DPP)
Term Name NES FDR q-val Tag % Leading Edge Genes
B cell receptor signaling pathway 1.96 0.00e+0 71/81 (87.65%) IFITM1;FOS;NFKBIA;...
Cell cycle 1.94 0.00e+0 110/124 (88.71%) GADD45B;CDC20;CCND3;...
Apoptosis 1.92 0.00e+0 126/168 (75%) GADD45B;BIRC5;BIRC3;...
DNA replication 1.85 2.16e-2 34/36 (94.44%) RPA2;MCM7;POLD4;...
PD-L1 expression and PD-1 checkpoint pathway in cancer 1.81 2.72e-2 79/89 (88.76%) FOS;NFKBIA;PIK3R1;...
Oocyte meiosis 1.79 2.47e-2 90/129 (69.77%) CDC20;CCNB2;PLK1;...
Colorectal cancer 1.79 2.12e-2 84/86 (97.67%) GADD45B;BIRC5;FOS;...
Endometrial cancer 1.77 2.01e-2 56/58 (96.55%) GADD45B;FOXO3;PIK3R1;...
Leishmaniasis 1.77 1.78e-2 67/77 (87.01%) FOS;C3;HLA-DPB1;...
p53 signaling pathway 1.76 1.98e-2 63/73 (86.3%) GADD45B;CCND3;CCNB2;...
T cell receptor signaling pathway 1.75 1.80e-2 93/104 (89.42%) FOS;NFKBIA;PIK3R1;...
Staphylococcus aureus infection 1.72 2.37e-2 72/95 (75.79%) KRT19;KRT23;C3;...
Progesterone-mediated oocyte maturation 1.70 3.14e-2 75/100 (75%) CCNB2;PLK1;MAD2L1;...
Measles 1.68 3.62e-2 133/139 (95.68%) CCND3;HSPA2;FOS;...
Leukocyte transendothelial migration 1.66 4.53e-2 90/114 (78.95%) CLDN3;PXN;PRKCB;...
Hepatitis B 1.65 4.48e-2 151/162 (93.21%) BIRC5;FOS;CCNA2;...
Yersinia infection 1.65 4.29e-2 120/137 (87.59%) FOS;PXN;NFKBIA;...
Th1 and Th2 cell differentiation 1.63 4.60e-2 80/92 (86.96%) FOS;HLA-DPB1;NFKBIA;...
Protein export -1.80 1.80e-2 17/23 (73.91%) SEC62;SRP72;SEC63;...
Lysosome -1.91 5.34e-3 115/128 (89.84%) AP1S2;CTSV;CTNS;...
Protein processing in endoplasmic reticulum -1.93 8.01e-3 127/171 (74.27%) DNAJC3;ERO1B;SEC61A2;...
Collecting duct acid secretion -2.10 0.00e+0 22/27 (81.48%) ATP6V1B2;ATP6V0E2;ATP6V1D;...
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Pharmacogenomic Perturbation Across Diseases and Tissues

Fibroblast
Nasopharyngeal carcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
FIBRNPC CVCL_UK07 Homo sapiens 10uM 6H, 24H