| Protein digestion and absorption |
1.83 |
9.32e-2 |
78/103 (75.73%) |
FXYD2;SLC3A1;PRSS1;...
|
| Vitamin digestion and absorption |
1.63 |
4.24e-1 |
17/24 (70.83%) |
APOB;APOA1;CUBN;...
|
| Proximal tubule bicarbonate reclamation |
1.60 |
3.76e-1 |
21/23 (91.3%) |
FXYD2;GLS;PCK1;...
|
| Renin-angiotensin system |
1.57 |
3.52e-1 |
20/23 (86.96%) |
ENPEP;ANPEP;ACE2;...
|
| Base excision repair |
1.57 |
2.89e-1 |
29/33 (87.88%) |
POLE;POLD2;POLE2;...
|
| Bladder cancer |
1.56 |
2.80e-1 |
40/41 (97.56%) |
E2F2;FGFR3;KRAS;...
|
| One carbon pool by folate |
1.56 |
2.44e-1 |
15/20 (75%) |
MTR;SHMT1;TYMS;...
|
| Cell cycle |
1.49 |
4.01e-1 |
110/124 (88.71%) |
E2F2;CCNE1;PLK1;...
|
| Carbohydrate digestion and absorption |
1.45 |
4.64e-1 |
37/47 (78.72%) |
FXYD2;MGAM;SLC37A4;...
|
| Central carbon metabolism in cancer |
1.43 |
4.48e-1 |
67/70 (95.71%) |
GLS;FGFR3;SIRT3;...
|
| Pancreatic secretion |
1.42 |
4.42e-1 |
87/102 (85.29%) |
FXYD2;CLCA2;PRSS1;...
|
| Insulin secretion |
1.42 |
4.09e-1 |
75/86 (87.21%) |
FXYD2;SNAP25;SLC2A2;...
|
| Pyrimidine metabolism |
1.42 |
3.99e-1 |
40/56 (71.43%) |
CDA;DPYS;RRM2;...
|
| Pentose and glucuronate interconversions |
1.40 |
3.98e-1 |
17/34 (50%) |
UGT2A3;AKR1B10;UGT2B28;...
|
| Starch and sucrose metabolism |
1.40 |
3.72e-1 |
25/36 (69.44%) |
MGAM;PYGM;GBA3;...
|
| Cardiac muscle contraction |
1.38 |
4.24e-1 |
64/87 (73.56%) |
FXYD2;COX7B;ATP1A2;...
|
| Adrenergic signaling in cardiomyocytes |
1.37 |
4.04e-1 |
130/150 (86.67%) |
FXYD2;CALML5;CALML3;...
|
| Cholesterol metabolism |
1.36 |
4.16e-1 |
44/50 (88%) |
APOB;APOA1;LRP2;...
|
| Cysteine and methionine metabolism |
1.36 |
4.00e-1 |
43/50 (86%) |
BHMT2;MTR;SRM;...
|
| Fructose and mannose metabolism |
1.35 |
4.06e-1 |
30/33 (90.91%) |
ALDOB;AKR1B10;PFKM;...
|
| FoxO signaling pathway |
1.35 |
3.88e-1 |
118/131 (90.08%) |
PLK2;SGK1;KLF2;...
|
| Melanogenesis |
1.34 |
3.90e-1 |
74/101 (73.27%) |
CALML5;CALML3;FZD2;...
|
| Galactose metabolism |
1.32 |
4.18e-1 |
26/31 (83.87%) |
MGAM;AKR1B10;PFKM
|
| Drug metabolism |
1.31 |
4.30e-1 |
78/151 (51.66%) |
GSTA1;CDA;UGT2A3;...
|
| Aldosterone synthesis and secretion |
1.29 |
4.78e-1 |
85/98 (86.73%) |
NR4A2;CALML5;CALML3;...
|
| D-Glutamine and D-glutamate metabolism |
1.29 |
4.68e-1 |
5/5 (100%) |
GLS;GLUD1
|
| Phototransduction |
1.28 |
4.88e-1 |
21/29 (72.41%) |
CALML5;CALML3
|
| Aldosterone-regulated sodium reabsorption |
1.27 |
4.79e-1 |
34/37 (91.89%) |
SGK1;FXYD2;KRAS;...
|
| Non-small cell lung cancer |
1.26 |
5.02e-1 |
70/72 (97.22%) |
E2F2;KRAS;TGFA;...
|
| Bile secretion |
1.26 |
5.01e-1 |
68/90 (75.56%) |
FXYD2;UGT2A3;ABCC4;...
|
| Influenza A |
-1.37 |
3.26e-1 |
156/172 (90.7%) |
CIITA;BID;APAF1;...
|
| Vibrio cholerae infection |
-1.38 |
3.25e-1 |
44/50 (88%) |
ATP6V0D1;TJP1;PLCG2;...
|
| NF-kappa B signaling pathway |
-1.38 |
3.29e-1 |
90/104 (86.54%) |
NFKB1;IL1R1;PLAU;...
|
| Ribosome |
-1.39 |
3.18e-1 |
113/158 (71.52%) |
RPS15A;RPL12;RPLP0;...
|
| Hippo signaling pathway |
-1.39 |
3.24e-1 |
120/186 (64.52%) |
ACTB;SCRIB;PPP1CC;...
|
| Cell adhesion molecules |
-1.40 |
3.09e-1 |
118/148 (79.73%) |
HLA-F;ITGAL;CDH5;...
|
| Herpes simplex virus 1 infection |
-1.40 |
3.17e-1 |
165/498 (33.13%) |
SRC;BID;APAF1;...
|
| Mineral absorption |
-1.42 |
2.87e-1 |
48/60 (80%) |
MT1M;HMOX1;SLC11A2;...
|
| N-Glycan biosynthesis |
-1.42 |
3.00e-1 |
38/50 (76%) |
MAN1A2;DPAGT1;MGAT4A;...
|
| Ether lipid metabolism |
-1.43 |
2.96e-1 |
32/49 (65.31%) |
PLD1;ENPP2;PLPP1;...
|
| Osteoclast differentiation |
-1.43 |
3.05e-1 |
117/127 (92.13%) |
PLCG2;SYK;AKT3;...
|
| Pertussis |
-1.44 |
3.09e-1 |
64/76 (84.21%) |
CASP3;PYCARD;C4BPA;...
|
| Transcriptional misregulation in cancer |
-1.45 |
2.94e-1 |
158/192 (82.29%) |
NFKB1;SP1;FLI1;...
|
| Sulfur metabolism |
-1.46 |
2.90e-1 |
9/10 (90%) |
SQOR;SELENBP1;ETHE1
|
| Adherens junction |
-1.47 |
3.00e-1 |
63/71 (88.73%) |
CSNK2A2;RAC3;SSX2IP;...
|
| Coronavirus disease |
-1.49 |
2.73e-1 |
215/232 (92.67%) |
RPL41;RPL32;PIK3CB;...
|
| Legionellosis |
-1.49 |
2.63e-1 |
51/57 (89.47%) |
TLR5;APAF1;RAB1B;...
|
| Measles |
-1.50 |
2.80e-1 |
133/139 (95.68%) |
IKBKB;CSNK2B;RAB9A;...
|
| African trypanosomiasis |
-1.50 |
2.82e-1 |
32/37 (86.49%) |
F2RL1;ICAM1;PLCB1;...
|
| Tyrosine metabolism |
-1.53 |
2.47e-1 |
30/36 (83.33%) |
ADH1C;ADH5;GSTZ1;...
|
| Malaria |
-1.53 |
2.65e-1 |
44/50 (88%) |
LRP1;THBS2;CCL2;...
|
| NOD-like receptor signaling pathway |
-1.54 |
2.57e-1 |
145/181 (80.11%) |
HSP90AA1;CCL2;CASP1;...
|
| Other glycan degradation |
-1.56 |
2.53e-1 |
13/18 (72.22%) |
ENGASE;HEXA;MAN2B2;...
|
| Yersinia infection |
-1.56 |
2.85e-1 |
120/137 (87.59%) |
PYCARD;AKT3;MAP2K6;...
|
| Various types of N-glycan biosynthesis |
-1.61 |
2.22e-1 |
26/39 (66.67%) |
MAN1A2;MGAT4A;B4GALT1;...
|
| Tight junction |
-1.62 |
2.37e-1 |
130/169 (76.92%) |
CD1E;PARD6B;PRKAA2;...
|
| Pathogenic Escherichia coli infection |
-1.63 |
2.70e-1 |
152/197 (77.16%) |
ARPC4;NFKBIB;GNA12;...
|
| Shigellosis |
-1.64 |
2.93e-1 |
180/246 (73.17%) |
ILK;ARPC4;NFKBIB;...
|
| Primary bile acid biosynthesis |
-1.77 |
1.74e-1 |
15/17 (88.24%) |
SLC27A5;AMACR;SCP2;...
|
| Ferroptosis |
-1.80 |
2.22e-1 |
36/41 (87.8%) |
HMOX1;STEAP3;SLC11A2;...
|
