| Steroid biosynthesis |
1.84 |
9.14e-2 |
19/20 (95%) |
SC5D;SQLE;LSS;...
|
| Central carbon metabolism in cancer |
1.74 |
1.93e-1 |
67/70 (95.71%) |
PFKM;KIT;G6PD;...
|
| IL-17 signaling pathway |
1.63 |
4.20e-1 |
84/94 (89.36%) |
S100A8;S100A9;S100A7;...
|
| Oxidative phosphorylation |
1.61 |
3.53e-1 |
93/133 (69.92%) |
ATP6V1A;SDHD;TCIRG1;...
|
| Collecting duct acid secretion |
1.56 |
4.06e-1 |
22/27 (81.48%) |
ATP6V1A;CA2;TCIRG1;...
|
| Thermogenesis |
1.54 |
4.01e-1 |
173/232 (74.57%) |
GNAS;MAP3K5;KDM1A;...
|
| Glutathione metabolism |
1.46 |
5.58e-1 |
43/57 (75.44%) |
G6PD;ANPEP;IDH2;...
|
| Diabetic cardiomyopathy |
1.35 |
5.76e-1 |
162/203 (79.8%) |
G6PD;AGT;CD36;...
|
| Adipocytokine signaling pathway |
1.35 |
5.77e-1 |
64/69 (92.75%) |
CD36;IRS1;NPY;...
|
| Galactose metabolism |
1.34 |
5.54e-1 |
26/31 (83.87%) |
PFKM;PFKP;AKR1B10;...
|
| Glycosaminoglycan biosynthesis |
1.34 |
5.54e-1 |
40/58 (68.97%) |
HS2ST1;CHST2;CHST11;...
|
| Synaptic vesicle cycle |
1.33 |
5.51e-1 |
63/78 (80.77%) |
ATP6V1A;SLC6A3;CLTC;...
|
| Cardiac muscle contraction |
1.32 |
5.45e-1 |
64/87 (73.56%) |
ATP2A2;ATP2A1;MYL2;...
|
| mRNA surveillance pathway |
1.29 |
5.82e-1 |
71/98 (72.45%) |
PPP2CA;NXT2;TARDBP;...
|
| Melanogenesis |
1.28 |
5.83e-1 |
74/101 (73.27%) |
GNAS;KIT;FZD6;...
|
| Rap1 signaling pathway |
1.28 |
5.69e-1 |
184/210 (87.62%) |
GNAS;ANGPT1;KIT;...
|
| Epithelial cell signaling in Helicobacter pylori infect... |
1.28 |
5.57e-1 |
62/70 (88.57%) |
SRC;CXCL8;ATP6V1A;...
|
| Legionellosis |
1.28 |
5.42e-1 |
51/57 (89.47%) |
CXCL8;ITGB2;MYD88;...
|
| Amoebiasis |
1.28 |
5.32e-1 |
99/102 (97.06%) |
GNAS;CXCL8;FN1;...
|
| Estrogen signaling pathway |
1.28 |
5.18e-1 |
119/137 (86.86%) |
KRT19;GNAS;KRT15;...
|
| PPAR signaling pathway |
1.27 |
5.28e-1 |
66/74 (89.19%) |
FABP5;CD36;SCD;...
|
| Adrenergic signaling in cardiomyocytes |
1.26 |
5.25e-1 |
130/150 (86.67%) |
GNAS;AGT;ATP2A2;...
|
| Pathways in cancer |
1.26 |
5.12e-1 |
474/531 (89.27%) |
GNAS;CDKN1B;KIT;...
|
| Type II diabetes mellitus |
1.26 |
5.01e-1 |
42/46 (91.3%) |
IRS1;PKM;SOCS1;...
|
| Phospholipase D signaling pathway |
1.26 |
5.02e-1 |
134/148 (90.54%) |
GNAS;KIT;CXCL8;...
|
| Vitamin digestion and absorption |
1.26 |
4.92e-1 |
17/24 (70.83%) |
APOB;SLC19A2;APOA1;...
|
| Thyroid hormone synthesis |
1.26 |
4.88e-1 |
66/75 (88%) |
GNAS;PLCB1;ADCY7;...
|
| Cushing syndrome |
1.25 |
4.81e-1 |
125/155 (80.65%) |
GNAS;CDKN1B;AGT;...
|
| D-Glutamine and D-glutamate metabolism |
1.22 |
5.82e-1 |
5/5 (100%) |
GLUD1;GLUD2;GLS
|
| Cortisol synthesis and secretion |
1.22 |
5.74e-1 |
58/65 (89.23%) |
GNAS;AGT;KCNK3;...
|
| One carbon pool by folate |
-1.25 |
5.16e-1 |
15/20 (75%) |
MTHFD2L;DHFR;MTHFD2;...
|
| Arginine biosynthesis |
-1.25 |
5.22e-1 |
17/22 (77.27%) |
NOS2;OTC;ARG1;...
|
| p53 signaling pathway |
-1.26 |
4.93e-1 |
63/73 (86.3%) |
CHEK2;CHEK1;PTEN;...
|
| SNARE interactions in vesicular transport |
-1.27 |
5.06e-1 |
19/33 (57.58%) |
STX2;STX8;GOSR2;...
|
| Starch and sucrose metabolism |
-1.30 |
4.86e-1 |
25/36 (69.44%) |
GYS2;SI;PYGB;...
|
| Retinol metabolism |
-1.30 |
4.92e-1 |
41/68 (60.29%) |
CYP1A2;CYP2B6;CYP1A1;...
|
| Epstein-Barr virus infection |
-1.30 |
4.98e-1 |
189/202 (93.56%) |
IFNAR2;STAT2;IKBKB;...
|
| TGF-beta signaling pathway |
-1.31 |
4.88e-1 |
81/94 (86.17%) |
TGIF1;BMP5;HAMP;...
|
| Peroxisome |
-1.32 |
4.79e-1 |
72/82 (87.8%) |
XDH;ECH1;HAO2;...
|
| Autoimmune thyroid disease |
-1.33 |
4.67e-1 |
46/53 (86.79%) |
HLA-DPA1;HLA-C;HLA-E;...
|
| Selenocompound metabolism |
-1.35 |
4.40e-1 |
11/17 (64.71%) |
TXNRD1;KYAT3;CTH;...
|
| Sulfur relay system |
-1.35 |
4.50e-1 |
5/8 (62.5%) |
MOCS3;MOCS2;TST;...
|
| Type I diabetes mellitus |
-1.38 |
3.76e-1 |
38/43 (88.37%) |
HLA-DPA1;HLA-C;HLA-E;...
|
| Pentose and glucuronate interconversions |
-1.38 |
3.98e-1 |
17/34 (50%) |
GUSB;AKR1B1;UGT2B28;...
|
| Allograft rejection |
-1.39 |
4.09e-1 |
32/38 (84.21%) |
HLA-DPA1;HLA-C;HLA-E;...
|
| Alanine, aspartate and glutamate metabolism |
-1.40 |
4.07e-1 |
27/37 (72.97%) |
ALDH4A1;ASL;ALDH5A1;...
|
| Drug metabolism |
-1.40 |
4.09e-1 |
78/151 (51.66%) |
CYP1A2;CYP2B6;GMPS;...
|
| Basal transcription factors |
-1.43 |
3.64e-1 |
37/45 (82.22%) |
GTF2I;TAF12;TAF10;...
|
| Ascorbate and aldarate metabolism |
-1.43 |
3.72e-1 |
15/30 (50%) |
KL;UGT2A3;ALDH2;...
|
| Complement and coagulation cascades |
-1.44 |
3.75e-1 |
76/85 (89.41%) |
BDKRB1;CFHR5;F2R;...
|
| NF-kappa B signaling pathway |
-1.45 |
3.67e-1 |
90/104 (86.54%) |
RELA;PLAU;TRAF1;...
|
| Non-homologous end-joining |
-1.49 |
3.11e-1 |
11/13 (84.62%) |
DNTT;POLM;POLL;...
|
| Graft-versus-host disease |
-1.50 |
3.21e-1 |
32/42 (76.19%) |
HLA-DPA1;HLA-C;HLA-E;...
|
| Cellular senescence |
-1.50 |
3.55e-1 |
139/156 (89.1%) |
E2F5;KRAS;HIPK3;...
|
| Glycine, serine and threonine metabolism |
-1.60 |
1.75e-1 |
31/40 (77.5%) |
AOC2;SHMT2;MAOB;...
|
| Caffeine metabolism |
-1.62 |
1.63e-1 |
5/6 (83.33%) |
XDH;CYP1A2;CYP2A6;...
|
| Sulfur metabolism |
-1.65 |
1.50e-1 |
9/10 (90%) |
SQOR;SELENBP1;TST;...
|
| Mineral absorption |
-1.67 |
1.47e-1 |
48/60 (80%) |
SLC30A1;VDR;MT2A;...
|
| Aminoacyl-tRNA biosynthesis |
-1.69 |
1.72e-1 |
15/66 (22.73%) |
LARS2;SARS2;FARSA;...
|
| Porphyrin and chlorophyll metabolism |
-1.85 |
7.86e-2 |
23/43 (53.49%) |
HMOX2;GUSB;UGT2B28;...
|
