| ECM-receptor interaction |
1.83 |
7.71e-2 |
80/88 (90.91%) |
VWF;THBS4;THBS1;...
|
| Retinol metabolism |
1.78 |
6.26e-2 |
41/68 (60.29%) |
ALDH1A1;ADH1B;ALDH1A3;...
|
| PPAR signaling pathway |
1.72 |
1.03e-1 |
66/74 (89.19%) |
SORBS1;PLTP;FABP4;...
|
| AMPK signaling pathway |
1.63 |
1.86e-1 |
106/120 (88.33%) |
IGF1;ADIPOQ;IGF1R;...
|
| Renin-angiotensin system |
1.59 |
2.18e-1 |
20/23 (86.96%) |
ANPEP;AGTR1;CTSG;...
|
| Hedgehog signaling pathway |
1.57 |
2.23e-1 |
43/56 (76.79%) |
GLI2;CSNK1D;CCND2;...
|
| AGE-RAGE signaling pathway in diabetic complications |
1.55 |
2.48e-1 |
97/100 (97%) |
AGTR1;EGR1;TGFBR2;...
|
| N-Glycan biosynthesis |
1.54 |
2.55e-1 |
38/50 (76%) |
MAN1A1;ST6GAL1;GANAB;...
|
| DNA replication |
1.52 |
2.72e-1 |
34/36 (94.44%) |
PCNA;FEN1;POLD1;...
|
| Other types of O-glycan biosynthesis |
1.52 |
2.49e-1 |
29/47 (61.7%) |
MFNG;GALNT6;ST6GAL1;...
|
| Focal adhesion |
1.51 |
2.64e-1 |
180/201 (89.55%) |
PDGFC;VWF;THBS4;...
|
| Malaria |
1.46 |
3.61e-1 |
44/50 (88%) |
THBS4;TGFB3;THBS1;...
|
| Fatty acid degradation |
1.46 |
3.43e-1 |
40/43 (93.02%) |
ACAA2;ADH1B;ACSL1;...
|
| Protein export |
1.45 |
3.24e-1 |
17/23 (73.91%) |
SEC61G;OXA1L;SEC11A;...
|
| TGF-beta signaling pathway |
1.45 |
3.03e-1 |
81/94 (86.17%) |
TGFBR2;TGFB3;THBS1;...
|
| PI3K-Akt signaling pathway |
1.44 |
3.32e-1 |
317/354 (89.55%) |
PDGFC;VWF;THBS4;...
|
| Circadian rhythm |
1.42 |
3.75e-1 |
26/31 (83.87%) |
PER3;CSNK1D;PER2;...
|
| Proteoglycans in cancer |
1.40 |
4.05e-1 |
172/205 (83.9%) |
IGF1;THBS1;CAV2;...
|
| Human papillomavirus infection |
1.40 |
3.85e-1 |
284/331 (85.8%) |
VWF;THBS4;THBS1;...
|
| Arrhythmogenic right ventricular cardiomyopathy |
1.39 |
3.73e-1 |
70/77 (90.91%) |
DMD;TCF7L1;LAMA2;...
|
| Basal cell carcinoma |
1.38 |
3.89e-1 |
41/63 (65.08%) |
GLI2;TCF7L1;FZD7;...
|
| alpha-Linolenic acid metabolism |
1.38 |
3.74e-1 |
17/25 (68%) |
PLA2G2A;FADS2;ACOX1;...
|
| Dilated cardiomyopathy |
1.37 |
3.81e-1 |
86/96 (89.58%) |
IGF1;TGFB3;DMD;...
|
| Systemic lupus erythematosus |
1.37 |
3.79e-1 |
45/135 (33.33%) |
C1QB;C7;HLA-DPB1;...
|
| Regulation of lipolysis in adipocytes |
1.37 |
3.64e-1 |
52/55 (94.55%) |
FABP4;MGLL;PLIN1;...
|
| Inflammatory bowel disease |
1.35 |
3.83e-1 |
58/65 (89.23%) |
TGFB3;HLA-DPB1;IL18;...
|
| FoxO signaling pathway |
1.34 |
4.05e-1 |
118/131 (90.08%) |
IGF1;TGFBR2;TGFB3;...
|
| Alcoholism |
1.33 |
3.98e-1 |
86/186 (46.24%) |
HDAC6;KRAS;GNG11;...
|
| Type I diabetes mellitus |
1.33 |
4.00e-1 |
38/43 (88.37%) |
PTPRN2;HLA-DPB1;PRF1;...
|
| Ovarian steroidogenesis |
1.32 |
3.99e-1 |
41/51 (80.39%) |
IGF1;IGF1R;CYP17A1;...
|
| Autophagy |
-1.18 |
5.19e-1 |
113/169 (66.86%) |
RAB7A;TSC2;PIK3R3;...
|
| Glycosaminoglycan degradation |
-1.24 |
5.16e-1 |
19/19 (100%) |
GNS;GALNS;GLB1;...
|
| Cytosolic DNA-sensing pathway |
-1.25 |
5.04e-1 |
52/63 (82.54%) |
PYCARD;CXCL10;IL6;...
|
| Leukocyte transendothelial migration |
-1.25 |
5.08e-1 |
90/114 (78.95%) |
RAC1;RAPGEF4;CLDN4;...
|
| ErbB signaling pathway |
-1.25 |
5.18e-1 |
79/85 (92.94%) |
SHC3;STAT5B;PAK3;...
|
| Type II diabetes mellitus |
-1.28 |
4.72e-1 |
42/46 (91.3%) |
HK2;PKM;PKLR;...
|
| Gastric acid secretion |
-1.30 |
4.33e-1 |
63/76 (82.89%) |
ATP4B;ADCY8;KCNJ1;...
|
| Salmonella infection |
-1.30 |
4.45e-1 |
198/249 (79.52%) |
ARPC1B;MAP2K2;CSE1L;...
|
| Pentose phosphate pathway |
-1.31 |
4.39e-1 |
25/30 (83.33%) |
TKT;PFKP;ALDOB;...
|
| Cell adhesion molecules |
-1.31 |
4.48e-1 |
118/148 (79.73%) |
NCAM1;MAG;CADM3;...
|
| Pentose and glucuronate interconversions |
-1.31 |
4.62e-1 |
17/34 (50%) |
UGDH;UGT2B15;UGT2B17;...
|
| Central carbon metabolism in cancer |
-1.32 |
4.54e-1 |
67/70 (95.71%) |
IDH1;HK2;PKM;...
|
| Yersinia infection |
-1.34 |
4.37e-1 |
120/137 (87.59%) |
ACTB;NFKBIA;ELMO1;...
|
| Biosynthesis of unsaturated fatty acids |
-1.35 |
4.18e-1 |
21/27 (77.78%) |
FADS1;SCD;HACD2;...
|
| Glycosphingolipid biosynthesis |
-1.35 |
4.38e-1 |
37/57 (64.91%) |
GLA;FUT9;GLB1;...
|
| Intestinal immune network for IgA production |
-1.35 |
4.59e-1 |
38/48 (79.17%) |
ITGB7;CCR9;HLA-DOB;...
|
| Lysosome |
-1.35 |
4.83e-1 |
115/128 (89.84%) |
GM2A;SORT1;CTSB;...
|
| Insulin secretion |
-1.35 |
4.97e-1 |
75/86 (87.21%) |
ADCY8;KCNN3;PRKCB;...
|
| Estrogen signaling pathway |
-1.37 |
4.81e-1 |
119/137 (86.86%) |
ADCY8;FOS;KCNJ9;...
|
| Oxidative phosphorylation |
-1.38 |
4.56e-1 |
93/133 (69.92%) |
NDUFV2;COX7B;CYC1;...
|
| SNARE interactions in vesicular transport |
-1.40 |
4.35e-1 |
19/33 (57.58%) |
STX16;STX4;STX2;...
|
| Bacterial invasion of epithelial cells |
-1.41 |
4.41e-1 |
59/77 (76.62%) |
ARHGEF26;CLTC;ITGB1;...
|
| Endometrial cancer |
-1.41 |
4.62e-1 |
56/58 (96.55%) |
AXIN1;APC2;SOS2;...
|
| GABAergic synapse |
-1.41 |
5.04e-1 |
76/89 (85.39%) |
ADCY8;GABRP;GLS2;...
|
| NOD-like receptor signaling pathway |
-1.43 |
5.10e-1 |
145/181 (80.11%) |
HSP90AB1;NFKBIA;PLCB4;...
|
| Maturity onset diabetes of the young |
-1.54 |
4.06e-1 |
21/26 (80.77%) |
FOXA2;PKLR;MNX1;...
|
| Toll-like receptor signaling pathway |
-1.57 |
3.95e-1 |
94/104 (90.38%) |
IFNA4;MAP2K2;IFNA1;...
|
| Nicotine addiction |
-1.59 |
4.42e-1 |
32/40 (80%) |
GABRR1;CHRNB2;GABRG2;...
|
| Vitamin digestion and absorption |
-1.63 |
4.29e-1 |
17/24 (70.83%) |
APOA1;SLC19A2;APOB;...
|
| Galactose metabolism |
-1.77 |
1.78e-1 |
26/31 (83.87%) |
HK2;SI;PFKP;...
|
