Details of the Drug Pharmacogenomic Perturbation Atlas

N-arachidonoylglycine Drug Info

Cross-matching ID

PubChem CID

5283389

ChEBI ID

CHEMBL161343

CAS Number

CAS 179113-91-8

TTD Drug ID

D01ZHW

General Information of Drug (ID: DM85RJ1)

Consensus Signature of Drug Pharmacogenomic Perturbation (DPP)

Term Name	NES	FDR q-val	Tag %	Leading Edge Genes
DNA replication	1.89	3.41e-2	34/36 (94.44%)	POLE3;RFC3;POLE2;...
Spliceosome	1.82	4.26e-2	101/150 (67.33%)	HSPA1A;HSPA2;LSM5;...
Fc gamma R-mediated phagocytosis	-1.78	4.82e-2	79/97 (81.44%)	PIP5K1C;AKT2;PRKCG;...
Nicotinate and nicotinamide metabolism	-1.86	1.89e-2	25/35 (71.43%)	SIRT7;NAMPT;NNT;...
N-Glycan biosynthesis	-1.89	2.27e-2	38/50 (76%)	B4GALT2;DPAGT1;B4GALT3;...
Staphylococcus aureus infection	-2.02	1.13e-2	72/95 (75.79%)	C1R;HLA-DPB1;HLA-DRA;...

Pharmacogenomic Perturbation Across Diseases and Tissues

Bone

Osteosarcoma

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
U-2 OS	CVCL_0042	Homo sapiens	1.11uM	6H

Breast

Breast adenocarcinoma

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
MCF7	CVCL_0031	Homo sapiens	10uM	6H, 24H

Colon

Colorectal adenocarcinoma

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
HT-29	CVCL_0320	Homo sapiens	10uM	6H, 24H

Kidney

Normal (Immortalized)

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
HA1E	CVCL_0284	Homo sapiens	10uM	6H, 24H

Lung

Lung adenocarcinoma

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
A549	CVCL_0023	Homo sapiens	10uM	6H, 24H

Non-small cell lung carcinoma

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
HCC515	CVCL_5134	Homo sapiens	10uM	6H

Prostate

Prostate carcinoma

Skin

Melanoma

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
A-375	CVCL_0132	Homo sapiens	10uM	6H, 24H