| Complement and coagulation cascades |
1.75 |
2.77e-1 |
76/85 (89.41%) |
PLAT;C1QA;C4BPA;...
|
| Ferroptosis |
1.66 |
2.94e-1 |
36/41 (87.8%) |
CP;TFRC;CYBB;...
|
| Pertussis |
1.65 |
2.19e-1 |
64/76 (84.21%) |
TLR4;CD14;IRF8;...
|
| Protein processing in endoplasmic reticulum |
1.56 |
3.81e-1 |
127/171 (74.27%) |
STUB1;EDEM1;SSR1;...
|
| Mannose type O-glycan biosynthesis |
1.52 |
4.24e-1 |
14/23 (60.87%) |
B4GALT3;B4GALT1;RXYLT1;...
|
| Pantothenate and CoA biosynthesis |
1.51 |
3.92e-1 |
14/21 (66.67%) |
ALDH3A2;DPYD;PANK2;...
|
| Toll-like receptor signaling pathway |
1.48 |
4.25e-1 |
94/104 (90.38%) |
TLR4;CXCL9;CD14;...
|
| Legionellosis |
1.44 |
5.11e-1 |
51/57 (89.47%) |
TLR4;CD14;C3;...
|
| Caffeine metabolism |
1.44 |
4.71e-1 |
5/6 (83.33%) |
CYP2A6;NAT2;CYP1A2;...
|
| N-Glycan biosynthesis |
1.42 |
4.72e-1 |
38/50 (76%) |
DOLPP1;ST6GAL1;B4GALT3;...
|
| Arachidonic acid metabolism |
1.42 |
4.30e-1 |
48/61 (78.69%) |
PLA2G2A;GPX1;PTGDS;...
|
| Signaling pathways regulating pluripotency of stem cell... |
1.42 |
3.99e-1 |
110/143 (76.92%) |
INHBB;PCGF2;ID1;...
|
| alpha-Linolenic acid metabolism |
1.38 |
5.01e-1 |
17/25 (68%) |
PLA2G2A;PLA2G2D;FADS2;...
|
| Ribosome biogenesis in eukaryotes |
1.37 |
4.91e-1 |
52/108 (48.15%) |
POP5;NMD3;NXT1;...
|
| Protein export |
1.37 |
4.74e-1 |
17/23 (73.91%) |
SEC61G;SRP72;SEC61B;...
|
| Systemic lupus erythematosus |
1.37 |
4.48e-1 |
45/135 (33.33%) |
CD86;C1QA;C3;...
|
| Linoleic acid metabolism |
1.36 |
4.33e-1 |
21/29 (72.41%) |
PLA2G2A;PLA2G2D;PLAAT3;...
|
| Ether lipid metabolism |
1.34 |
4.89e-1 |
32/49 (65.31%) |
PLA2G2A;PLPP3;PLA2G2D;...
|
| Porphyrin and chlorophyll metabolism |
1.31 |
5.54e-1 |
23/43 (53.49%) |
CP;PPOX;COX10;...
|
| Hematopoietic cell lineage |
1.26 |
5.97e-1 |
90/99 (90.91%) |
CD14;TFRC;CD44;...
|
| Drug metabolism |
1.25 |
5.84e-1 |
78/151 (51.66%) |
TYMP;ITPA;CYP3A5;...
|
| Peroxisome |
1.23 |
5.95e-1 |
72/82 (87.8%) |
PECR;PIPOX;PEX2;...
|
| Mineral absorption |
1.22 |
5.95e-1 |
48/60 (80%) |
MT1M;MT1F;SLC30A1;...
|
| Ascorbate and aldarate metabolism |
1.22 |
5.80e-1 |
15/30 (50%) |
ALDH3A2;AKR1A1;ALDH1B1
|
| Pyrimidine metabolism |
1.22 |
5.79e-1 |
40/56 (71.43%) |
TYMP;NME3;ENTPD3;...
|
| Tryptophan metabolism |
1.22 |
5.65e-1 |
35/42 (83.33%) |
ALDH3A2;TDO2;IDO1;...
|
| Rheumatoid arthritis |
1.20 |
6.05e-1 |
78/93 (83.87%) |
TLR4;CD86;ANGPT1;...
|
| Aminoacyl-tRNA biosynthesis |
1.20 |
6.06e-1 |
15/66 (22.73%) |
LARS2;FARSA;GATC;...
|
| Ribosome |
1.17 |
5.98e-1 |
113/158 (71.52%) |
MRPS16;MRPS2;MRPL28;...
|
| Huntington disease |
1.17 |
5.92e-1 |
233/306 (76.14%) |
TGM2;GPX1;GPX3;...
|
| Renin-angiotensin system |
-1.31 |
4.70e-1 |
20/23 (86.96%) |
PRCP;ANPEP;CTSA;...
|
| Pentose and glucuronate interconversions |
-1.31 |
4.85e-1 |
17/34 (50%) |
CRYL1;UGP2;UGT2A3;...
|
| Alanine, aspartate and glutamate metabolism |
-1.34 |
4.27e-1 |
27/37 (72.97%) |
GLUD1;GLS;GLUD2;...
|
| B cell receptor signaling pathway |
-1.35 |
4.07e-1 |
71/81 (87.65%) |
PIK3R1;CD22;PRKCB;...
|
| Chronic myeloid leukemia |
-1.35 |
4.12e-1 |
72/76 (94.74%) |
CDK6;MAP2K2;GADD45B;...
|
| Osteoclast differentiation |
-1.36 |
4.04e-1 |
117/127 (92.13%) |
BTK;TGFBR2;TNFSF11;...
|
| Cellular senescence |
-1.37 |
4.03e-1 |
139/156 (89.1%) |
RAD9A;TGFBR2;CCNB2;...
|
| Non-homologous end-joining |
-1.37 |
4.07e-1 |
11/13 (84.62%) |
POLM;MRE11;XRCC5;...
|
| Gastric acid secretion |
-1.38 |
4.11e-1 |
63/76 (82.89%) |
CCKBR;MYLK;PRKCB;...
|
| Inflammatory mediator regulation of TRP channels |
-1.38 |
4.20e-1 |
82/98 (83.67%) |
SRC;PPP1CB;F2RL1;...
|
| Endocrine and other factor-regulated calcium reabsorpti... |
-1.39 |
3.92e-1 |
49/53 (92.45%) |
PRKCB;CALB1;CLTCL1;...
|
| Inositol phosphate metabolism |
-1.41 |
3.74e-1 |
66/73 (90.41%) |
PIP4K2B;MTMR14;INPP4B;...
|
| Transcriptional misregulation in cancer |
-1.41 |
3.95e-1 |
158/192 (82.29%) |
CDKN1B;MMP9;EYA1;...
|
| Fatty acid elongation |
-1.41 |
4.14e-1 |
19/27 (70.37%) |
PPT1;HACD1;ELOVL6;...
|
| Influenza A |
-1.41 |
4.28e-1 |
156/172 (90.7%) |
KPNA6;IL6;PRKCB;...
|
| Terpenoid backbone biosynthesis |
-1.42 |
4.36e-1 |
18/22 (81.82%) |
MVD;FNTA;ACAT1;...
|
| Arginine biosynthesis |
-1.43 |
4.28e-1 |
17/22 (77.27%) |
GLUD1;GLS;GLUD2;...
|
| Galactose metabolism |
-1.51 |
2.51e-1 |
26/31 (83.87%) |
B4GALT2;PFKM;GALT;...
|
| Pancreatic cancer |
-1.52 |
2.46e-1 |
75/76 (98.68%) |
TGFBR2;RALGDS;PIK3R1;...
|
| Mucin type O-glycan biosynthesis |
-1.53 |
2.54e-1 |
20/36 (55.56%) |
GALNT11;GALNT12;GALNT3;...
|
| Steroid biosynthesis |
-1.54 |
2.35e-1 |
19/20 (95%) |
MSMO1;FDFT1;LBR;...
|
| Phosphatidylinositol signaling system |
-1.55 |
2.44e-1 |
82/97 (84.54%) |
PIP4K2B;MTMR14;INPP4B;...
|
| Butanoate metabolism |
-1.56 |
2.47e-1 |
23/28 (82.14%) |
HADHA;HADH;OXCT1;...
|
| Synthesis and degradation of ketone bodies |
-1.57 |
2.51e-1 |
9/10 (90%) |
OXCT1;ACAT1;HMGCS1
|
| Cell cycle |
-1.58 |
2.63e-1 |
110/124 (88.71%) |
DBF4;CDKN1B;CDC25C;...
|
| Ovarian steroidogenesis |
-1.60 |
2.77e-1 |
41/51 (80.39%) |
CYP11A1;CGA;ADCY9;...
|
| Starch and sucrose metabolism |
-1.60 |
3.41e-1 |
25/36 (69.44%) |
GYS1;AGL;GPI;...
|
| D-Glutamine and D-glutamate metabolism |
-1.64 |
3.35e-1 |
5/5 (100%) |
GLUD1;GLS;GLUD2;...
|
| Homologous recombination |
-1.64 |
4.79e-1 |
35/41 (85.37%) |
BARD1;TOP3B;MUS81;...
|
| Protein digestion and absorption |
-1.82 |
7.89e-2 |
78/103 (75.73%) |
CTRL;COL5A2;COL9A3;...
|
