Details of the Drug Pharmacogenomic Perturbation Atlas

General Information of Drug (ID: DM9GSVQ)

Drug Name
Tasquinimod Drug Info
Synonyms TASQ
Cross-matching ID
PubChem CID
54682876
ChEBI ID
CHEMBL2107784
CAS Number
CAS 254964-60-8
TTD Drug ID
D02JMU

Consensus Signature of Drug Pharmacogenomic Perturbation (DPP)
Term Name NES FDR q-val Tag % Leading Edge Genes
Citrate cycle (TCA cycle) 1.85 4.15e-2 30/30 (100%) PCK1;IDH2;SUCLG2;...
Propanoate metabolism 1.85 2.76e-2 30/34 (88.24%) HIBCH;SUCLG2;DLD;...
Spliceosome 1.85 2.33e-2 101/150 (67.33%) SRSF7;SRSF1;SF3B1;...
Herpes simplex virus 1 infection 1.76 4.89e-2 165/498 (33.13%) DAXX;PDIA3;SRSF7;...
Epstein-Barr virus infection 1.73 4.79e-2 189/202 (93.56%) LYN;STAT3;TNFAIP3;...
Malaria -1.76 4.56e-2 44/50 (88%) KLRB1;TGFB2;THBS2;...
Glycerophospholipid metabolism -1.83 3.20e-2 71/98 (72.45%) PTDSS2;CDIPT;DGKA;...
Renin-angiotensin system -1.91 1.44e-2 20/23 (86.96%) MME;KLK2;AGTR1;...
Ether lipid metabolism -1.97 0.00e+0 32/49 (65.31%) PLA2G12A;PAFAH1B3;PLA2G1B;...
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Pharmacogenomic Perturbation Across Diseases and Tissues

Breast
Breast adenocarcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
MCF7 CVCL_0031 Homo sapiens 0.01uM - 10uM 24H
MDA-MB-231 CVCL_0062 Homo sapiens 0.01uM - 10uM 24H
Breast epithelium
Normal
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
MCF-10A CVCL_0598 Homo sapiens 0.01uM - 10uM 24H
Cervix
Cervical adenocarcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
HeLa CVCL_0030 Homo sapiens 0.01uM - 10uM 24H
Colon
Colorectal adenocarcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
HT-29 CVCL_0320 Homo sapiens 0.01uM - 10uM 24H
Kidney
Normal (Immortalized)
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
HA1E CVCL_0284 Homo sapiens 0.01uM - 10uM 24H
Normal (Transformed)
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
HEK293 CVCL_0045 Homo sapiens 0.01uM - 10uM 24H
Lung
Lung adenocarcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
A549 CVCL_0023 Homo sapiens 0.01uM - 10uM 24H
Pancreas
Pancreatic carcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
YAPC CVCL_1791 Homo sapiens 0.01uM - 10uM 24H
Peripheral blood
Acute monocytic leukemia
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
THP-1 CVCL_0006 Homo sapiens 0.01uM - 10uM 24H
T-cell acute lymphoblastic leukemia
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
Jurkat CVCL_0367 Homo sapiens 0.01uM - 10uM 24H
Prostate
Prostate carcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
PC-3 CVCL_0035 Homo sapiens 0.01uM - 10uM 24H
Skin
Melanoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
A-375 CVCL_0132 Homo sapiens 0.01uM - 10uM 24H