| Homologous recombination |
1.88 |
5.58e-2 |
35/41 (85.37%) |
SSBP1;TOPBP1;SEM1;...
|
| Ribosome |
1.79 |
1.19e-1 |
113/158 (71.52%) |
MRPS16;MRPL23;MRPL9;...
|
| Cysteine and methionine metabolism |
1.74 |
9.76e-2 |
43/50 (86%) |
LDHB;DNMT3B;ADI1;...
|
| Thiamine metabolism |
1.67 |
1.92e-1 |
12/15 (80%) |
AK4;AK2;ALPP;...
|
| Acute myeloid leukemia |
1.60 |
2.79e-1 |
66/67 (98.51%) |
MPO;RUNX1;BAD;...
|
| RNA polymerase |
1.57 |
2.69e-1 |
23/31 (74.19%) |
POLR2I;POLR2H;POLR2L;...
|
| AGE-RAGE signaling pathway in diabetic complications |
1.56 |
2.69e-1 |
97/100 (97%) |
COL4A5;CCL2;CDC42;...
|
| Glutathione metabolism |
1.53 |
2.88e-1 |
43/57 (75.44%) |
GSTM3;GSTP1;CHAC1;...
|
| Nitrogen metabolism |
1.53 |
2.65e-1 |
16/17 (94.12%) |
CA2;CA12;CA14;...
|
| Graft-versus-host disease |
1.52 |
2.71e-1 |
32/42 (76.19%) |
IL1A;HLA-DPB1;IL6;...
|
| Chemokine signaling pathway |
1.51 |
2.59e-1 |
163/192 (84.9%) |
CX3CR1;CCL2;CXCL12;...
|
| DNA replication |
1.50 |
2.60e-1 |
34/36 (94.44%) |
PCNA;POLE3;MCM6;...
|
| Drug metabolism |
1.49 |
2.63e-1 |
78/151 (51.66%) |
GSTM3;GSTP1;MPO;...
|
| Lysine degradation |
1.48 |
2.67e-1 |
51/63 (80.95%) |
ACAT2;DLD;BBOX1;...
|
| Pentose and glucuronate interconversions |
1.48 |
2.60e-1 |
17/34 (50%) |
UGP2;AKR1A1;AKR1B10;...
|
| One carbon pool by folate |
1.47 |
2.58e-1 |
15/20 (75%) |
MTHFD1;GART;TYMS;...
|
| Base excision repair |
1.47 |
2.49e-1 |
29/33 (87.88%) |
PCNA;POLE3;PARP2;...
|
| Small cell lung cancer |
1.47 |
2.44e-1 |
90/92 (97.83%) |
COL4A5;LAMC1;COL4A6;...
|
| Hedgehog signaling pathway |
1.46 |
2.51e-1 |
43/56 (76.79%) |
GRK2;GAS1;GLI3;...
|
| Non-alcoholic fatty liver disease |
1.44 |
2.85e-1 |
126/155 (81.29%) |
CDC42;IL1A;BID;...
|
| Chagas disease |
1.43 |
2.75e-1 |
93/102 (91.18%) |
CCL2;FADD;MAPK14;...
|
| IL-17 signaling pathway |
1.43 |
2.67e-1 |
84/94 (89.36%) |
S100A8;CCL2;S100A9;...
|
| Oxidative phosphorylation |
1.43 |
2.60e-1 |
93/133 (69.92%) |
PPA1;NDUFA3;ATP5MC2;...
|
| Pyrimidine metabolism |
1.40 |
2.89e-1 |
40/56 (71.43%) |
DPYD;TYMP;RRM1;...
|
| Cytokine-cytokine receptor interaction |
1.40 |
2.81e-1 |
246/295 (83.39%) |
CX3CR1;IL7R;CCL2;...
|
| Natural killer cell mediated cytotoxicity |
1.39 |
2.83e-1 |
99/131 (75.57%) |
TNFRSF10B;PAK1;BID;...
|
| Nucleotide excision repair |
1.39 |
2.83e-1 |
40/47 (85.11%) |
PCNA;POLE3;GTF2H3;...
|
| Folate biosynthesis |
1.38 |
2.88e-1 |
23/26 (88.46%) |
GGH;AKR1B10;ALPP;...
|
| Staphylococcus aureus infection |
1.38 |
2.84e-1 |
72/95 (75.79%) |
CFB;KRT14;FPR1;...
|
| Cytosolic DNA-sensing pathway |
1.36 |
2.88e-1 |
52/63 (82.54%) |
PYCARD;POLR2H;IKBKB;...
|
| Glycolysis / Gluconeogenesis |
-1.00 |
8.63e-1 |
56/67 (83.58%) |
LDHA;PKLR;ENO1;...
|
| Synaptic vesicle cycle |
-1.11 |
8.40e-1 |
63/78 (80.77%) |
ATP6V0D1;ATP6V1C1;STX1A;...
|
| Arginine and proline metabolism |
-1.12 |
8.28e-1 |
39/50 (78%) |
LAP3;CKB;GATM;...
|
| Mucin type O-glycan biosynthesis |
-1.12 |
8.45e-1 |
20/36 (55.56%) |
GCNT3;GALNT3;GALNT12
|
| Wnt signaling pathway |
-1.12 |
8.38e-1 |
124/166 (74.7%) |
TCF7L2;AXIN1;CTNND2;...
|
| Renin secretion |
-1.13 |
8.23e-1 |
61/69 (88.41%) |
PPP3CA;PDE1A;EDNRA;...
|
| Ovarian steroidogenesis |
-1.14 |
8.33e-1 |
41/51 (80.39%) |
ADCY3;HSD3B2;STAR;...
|
| Inositol phosphate metabolism |
-1.14 |
8.42e-1 |
66/73 (90.41%) |
PIKFYVE;PLCE1;MINPP1;...
|
| Alanine, aspartate and glutamate metabolism |
-1.14 |
8.42e-1 |
27/37 (72.97%) |
CPS1;ASNS;GLUD1;...
|
| AMPK signaling pathway |
-1.16 |
7.90e-1 |
106/120 (88.33%) |
SCD;MTOR;TSC2;...
|
| Hippo signaling pathway |
-1.17 |
7.91e-1 |
120/186 (64.52%) |
AREG;FZD7;APC2;...
|
| Glycosaminoglycan biosynthesis |
-1.17 |
7.94e-1 |
40/58 (68.97%) |
CHST12;B3GNT2;B4GALT4;...
|
| TGF-beta signaling pathway |
-1.18 |
7.65e-1 |
81/94 (86.17%) |
TGFBR1;INHBA;SMAD2;...
|
| Arachidonic acid metabolism |
-1.18 |
7.75e-1 |
48/61 (78.69%) |
CYP4F2;PLA2G5;ALOX15;...
|
| Protein digestion and absorption |
-1.19 |
7.64e-1 |
78/103 (75.73%) |
COL9A2;ELN;PRSS1;...
|
| Estrogen signaling pathway |
-1.19 |
7.87e-1 |
119/137 (86.86%) |
HBEGF;AKT1;EBAG9;...
|
| Basal cell carcinoma |
-1.19 |
8.11e-1 |
41/63 (65.08%) |
TCF7L2;AXIN1;GADD45G;...
|
| Colorectal cancer |
-1.21 |
7.65e-1 |
84/86 (97.67%) |
AREG;CYCS;APC2;...
|
| Parathyroid hormone synthesis, secretion and action |
-1.21 |
7.80e-1 |
98/106 (92.45%) |
LRP5;CDKN1A;PRKCA;...
|
| Cushing syndrome |
-1.21 |
8.01e-1 |
125/155 (80.65%) |
CACNA1G;CYP11B1;CACNA1D;...
|
| Type II diabetes mellitus |
-1.23 |
7.70e-1 |
42/46 (91.3%) |
CACNA1C;HK1;CACNA1G;...
|
| Nicotinate and nicotinamide metabolism |
-1.24 |
7.66e-1 |
25/35 (71.43%) |
SIRT7;NMNAT2;SIRT2;...
|
| Endocrine and other factor-regulated calcium reabsorpti... |
-1.24 |
7.88e-1 |
49/53 (92.45%) |
PRKCA;GNAQ;VDR;...
|
| Aldosterone synthesis and secretion |
-1.24 |
8.10e-1 |
85/98 (86.73%) |
ATP1B2;ITPR3;AGT;...
|
| Thyroid hormone signaling pathway |
-1.25 |
7.88e-1 |
112/121 (92.56%) |
NCOA1;MTOR;TSC2;...
|
| MicroRNAs in cancer |
-1.25 |
8.23e-1 |
146/310 (47.1%) |
TNXB;ST14;APC2;...
|
| alpha-Linolenic acid metabolism |
-1.26 |
8.49e-1 |
17/25 (68%) |
PLA2G1B;PLA2G12A;PLAAT3;...
|
| Glycerophospholipid metabolism |
-1.27 |
8.49e-1 |
71/98 (72.45%) |
AGPAT5;PLA2G1B;ADPRM;...
|
| Thyroid hormone synthesis |
-1.55 |
6.40e-1 |
66/75 (88%) |
PRKCA;GNAQ;PDIA4;...
|
| Steroid hormone biosynthesis |
-1.68 |
4.31e-1 |
43/61 (70.49%) |
UGT2B28;DHRS11;HSD11B1;...
|
