Details of the Drug Pharmacogenomic Perturbation Atlas

General Information of Drug (ID: DMAMCSR)

• Drug Name: acrolein Drug Info
• Synonyms: ACROLEIN; Acrylaldehyde; 2-Propenal; Propenal; 107-02-8; Acrylic aldehyde; Allyl aldehyde; prop-2-enal; Ethylene aldehyde; Acraldehyde; Aqualin; Magnacide H; 2-Propen-1-one; Aqualine; Slimicide; Crolean; Acquinite; Magnacide; Prop-2-en-1-al; Acrylaldehyd; Akroleina; Akrolein; Acroleine; Acroleina; Papite; Biocide; Aldeide acrilica; Aldehyde acrylique; Acraldehydeacroleina; polyacrolein; Propenaldehyde; trans-Acrolein; NSC 8819; Akrolein [Czech]; Propenal [Czech]; Rcra waste number P003; Magnacide H and B; Akroleina [Polish]; Acroleina [Italian]
• Cross-matching ID:
  PubChem CID: 7847
  ChEBI ID: CHEMBL721
  CAS Number: CAS 107-02-8
  TTD Drug ID: D0I0AA

Consensus Signature of Drug Pharmacogenomic Perturbation (DPP)

Term Name	NES	FDR q-val	Tag %	Leading Edge Genes
Estrogen signaling pathway	-1.84	4.59e-2	119/137 (86.86%)	KCNJ6;AKT2;CREB1;...
Dilated cardiomyopathy	-1.98	3.75e-2	86/96 (89.58%)	PLN;ITGA2B;ITGA1;...

Pharmacogenomic Perturbation Across Diseases and Tissues

Liver

Hepatoblastoma

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
Hep G2	CVCL_0027	Homo sapiens	1.25uM - 40uM	3H, 24H	Hide ▲