Details of the Drug Pharmacogenomic Perturbation Atlas

General Information of Drug (ID: DMAQ2LK)

Drug Name
Teicoplanin Drug Info
Synonyms Targocid (TN)
Cross-matching ID
PubChem CID
133065662
CAS Number
CAS 61036-62-2
TTD Drug ID
D0K6MW
INTEDE Drug ID
DR1542

Consensus Signature of Drug Pharmacogenomic Perturbation (DPP)
Term Name NES FDR q-val Tag % Leading Edge Genes
Fanconi anemia pathway 2.12 0.00e+0 36/54 (66.67%) BRCA1;FANCI;RAD51;...
DNA replication 2.11 0.00e+0 34/36 (94.44%) PCNA;POLE2;FEN1;...
Base excision repair 1.91 1.11e-2 29/33 (87.88%) PCNA;POLE2;FEN1;...
Ribosome biogenesis in eukaryotes 1.81 2.09e-2 52/108 (48.15%) NXT1;RPP40;NOP56;...
African trypanosomiasis 1.78 2.51e-2 32/37 (86.49%) VCAM1;HBB;PLCB3;...
Homologous recombination 1.78 2.09e-2 35/41 (85.37%) BRCA1;RAD51;TOPBP1;...
Nucleotide excision repair 1.76 2.03e-2 40/47 (85.11%) PCNA;POLE2;XPA;...
Mismatch repair 1.75 1.88e-2 22/23 (95.65%) PCNA;RFC4;RFC5;...
Ferroptosis -1.87 4.53e-2 36/41 (87.8%) SLC39A14;PCBP1;ACSL3;...
Mineral absorption -2.26 0.00e+0 48/60 (80%) SLC34A2;ATP1A2;ATP1B2;...
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Pharmacogenomic Perturbation Across Diseases and Tissues

Breast
Breast adenocarcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
MCF7 CVCL_0031 Homo sapiens 10uM 6H, 24H
Colon
Colorectal adenocarcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
HT-29 CVCL_0320 Homo sapiens 10uM 6H
Hematopoietic system
Normal
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
ASC CVCL_U602 Homo sapiens 10uM 24H
Kidney
Normal (Immortalized)
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
HA1E CVCL_0284 Homo sapiens 10uM 6H
Liver
Hepatoblastoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
Hep G2 CVCL_0027 Homo sapiens 10uM 6H
Lung
Lung adenocarcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
A549 CVCL_0023 Homo sapiens 10uM 6H, 24H
Non-small cell lung carcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
HCC515 CVCL_5134 Homo sapiens 10uM 6H
Prostate
Prostate carcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
PC-3 CVCL_0035 Homo sapiens 10uM 6H, 24H
VCaP CVCL_2235 Homo sapiens 10uM 6H, 24H
Skin
Melanoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
A-375 CVCL_0132 Homo sapiens 10uM 6H