| Porphyrin and chlorophyll metabolism |
1.83 |
5.74e-2 |
23/43 (53.49%) |
PPOX;CP;HEPH;...
|
| RNA transport |
1.71 |
1.72e-1 |
128/186 (68.82%) |
EIF1AY;CLNS1A;EIF3G;...
|
| Ferroptosis |
1.68 |
1.56e-1 |
36/41 (87.8%) |
SLC39A8;CP;FTH1;...
|
| Ribosome |
1.60 |
2.94e-1 |
113/158 (71.52%) |
RPS25;RPS4Y1;MRPS16;...
|
| Tyrosine metabolism |
1.56 |
3.35e-1 |
30/36 (83.33%) |
ADH5;TYRP1;MAOB;...
|
| Bile secretion |
1.55 |
3.16e-1 |
68/90 (75.56%) |
ABCG2;CA2;AQP1;...
|
| Drug metabolism |
1.52 |
3.64e-1 |
78/151 (51.66%) |
FMO5;IMPDH2;ADH5;...
|
| Asthma |
1.51 |
3.43e-1 |
25/31 (80.65%) |
CD40;FCER1A;PRG2;...
|
| Purine metabolism |
1.50 |
3.45e-1 |
102/129 (79.07%) |
PAPSS1;PDE4B;ADCY2;...
|
| Aminoacyl-tRNA biosynthesis |
1.49 |
3.47e-1 |
15/66 (22.73%) |
IARS2;WARS2;FARS2;...
|
| Glycosylphosphatidylinositol (GPI)-anchor biosynthesis |
1.48 |
3.37e-1 |
20/26 (76.92%) |
PIGB;PIGN;PIGV;...
|
| Retinol metabolism |
1.48 |
3.09e-1 |
41/68 (60.29%) |
ADH5;UGT2B28;ADH1C;...
|
| Vascular smooth muscle contraction |
1.45 |
3.61e-1 |
113/133 (84.96%) |
MYLK;MYH11;ACTG2;...
|
| Primary bile acid biosynthesis |
1.43 |
3.97e-1 |
15/17 (88.24%) |
HSD17B4;CYP27A1;CYP7B1;...
|
| DNA replication |
1.42 |
4.07e-1 |
34/36 (94.44%) |
PRIM1;MCM3;PRIM2;...
|
| Mismatch repair |
1.42 |
3.86e-1 |
22/23 (95.65%) |
MLH1;MSH2;RPA3;...
|
| Vitamin digestion and absorption |
1.40 |
4.12e-1 |
17/24 (70.83%) |
APOA1;LMBRD1;SLC5A6;...
|
| One carbon pool by folate |
1.39 |
4.15e-1 |
15/20 (75%) |
AMT;ATIC;TYMS;...
|
| Metabolism of xenobiotics by cytochrome P450 |
1.37 |
4.52e-1 |
49/77 (63.64%) |
ADH5;UGT2B28;GSTT1;...
|
| Steroid hormone biosynthesis |
1.37 |
4.36e-1 |
43/61 (70.49%) |
UGT2B28;HSD17B2;SULT1E1;...
|
| Cell cycle |
1.37 |
4.24e-1 |
110/124 (88.71%) |
E2F2;CDC20;CHEK1;...
|
| cGMP-PKG signaling pathway |
1.36 |
4.33e-1 |
145/167 (86.83%) |
NFATC3;MYLK;PPP3CA;...
|
| Transcriptional misregulation in cancer |
1.35 |
4.50e-1 |
158/192 (82.29%) |
CD40;ARNT2;MEIS1;...
|
| Vasopressin-regulated water reabsorption |
1.35 |
4.42e-1 |
40/44 (90.91%) |
AQP3;DYNC1I2;CREB3L2;...
|
| Proximal tubule bicarbonate reclamation |
1.33 |
4.64e-1 |
21/23 (91.3%) |
CA2;AQP1;SLC4A4;...
|
| RNA degradation |
1.32 |
4.87e-1 |
53/79 (67.09%) |
PABPC4;DCPS;BTG3;...
|
| Cocaine addiction |
1.31 |
4.78e-1 |
42/49 (85.71%) |
SLC18A2;GRIA2;NFKB1;...
|
| MicroRNAs in cancer |
1.31 |
4.63e-1 |
146/310 (47.1%) |
FGFR3;E2F2;CRK;...
|
| Amphetamine addiction |
1.31 |
4.49e-1 |
57/69 (82.61%) |
PPP3CA;SLC18A2;GRIA2;...
|
| Oocyte meiosis |
1.29 |
4.97e-1 |
90/129 (69.77%) |
CDC20;PPP3CA;ADCY2;...
|
| Salivary secretion |
-1.18 |
4.52e-1 |
76/93 (81.72%) |
ATP1B1;ADCY8;PLCB4;...
|
| Neurotrophin signaling pathway |
-1.18 |
4.50e-1 |
107/119 (89.92%) |
FRS2;AKT1;PRDM4;...
|
| HIF-1 signaling pathway |
-1.19 |
4.51e-1 |
105/109 (96.33%) |
HK1;FLT1;AKT1;...
|
| Taste transduction |
-1.19 |
4.50e-1 |
61/86 (70.93%) |
GABRA5;P2RX3;GABRA1;...
|
| Glucagon signaling pathway |
-1.19 |
4.44e-1 |
89/107 (83.18%) |
FBP1;PLCB4;PPP3CB;...
|
| Sphingolipid signaling pathway |
-1.19 |
4.51e-1 |
106/119 (89.08%) |
AKT1;SPHK1;ROCK2;...
|
| African trypanosomiasis |
-1.20 |
4.47e-1 |
32/37 (86.49%) |
PRKCA;HBB;IL6;...
|
| Sphingolipid metabolism |
-1.20 |
4.46e-1 |
32/49 (65.31%) |
SPHK2;DEGS1;PLPP3;...
|
| Epithelial cell signaling in Helicobacter pylori infect... |
-1.21 |
4.44e-1 |
62/70 (88.57%) |
ATP6V0E1;IKBKG;CSK;...
|
| Steroid biosynthesis |
-1.29 |
4.50e-1 |
19/20 (95%) |
LSS;TM7SF2;DHCR7;...
|
| IL-17 signaling pathway |
-1.32 |
4.30e-1 |
84/94 (89.36%) |
CSF2;MAPK14;IL1B;...
|
| Type II diabetes mellitus |
-1.33 |
4.30e-1 |
42/46 (91.3%) |
SOCS2;PIK3CB;HK2;...
|
| Autophagy |
-1.34 |
4.32e-1 |
113/169 (66.86%) |
TSC1;RRAS;MTMR3;...
|
| Tryptophan metabolism |
-1.36 |
3.86e-1 |
35/42 (83.33%) |
ALDH9A1;TDO2;CYP1B1;...
|
| Diabetic cardiomyopathy |
-1.36 |
4.00e-1 |
162/203 (79.8%) |
SDHA;NDUFB4;MPC2;...
|
| Hematopoietic cell lineage |
-1.37 |
4.08e-1 |
90/99 (90.91%) |
CD1D;ITGA2B;ITGA2;...
|
| Insulin signaling pathway |
-1.38 |
4.03e-1 |
121/137 (88.32%) |
TSC1;PRKAB2;PPP1CA;...
|
| Kaposi sarcoma-associated herpesvirus infection |
-1.38 |
4.22e-1 |
172/193 (89.12%) |
PTGS2;PDGFB;HRAS;...
|
| Carbohydrate digestion and absorption |
-1.38 |
4.24e-1 |
37/47 (78.72%) |
HK1;AKT1;ATP1A3;...
|
| Pentose phosphate pathway |
-1.39 |
4.43e-1 |
25/30 (83.33%) |
FBP1;ALDOC;RBKS;...
|
| Lysine degradation |
-1.42 |
4.13e-1 |
51/63 (80.95%) |
ACAT2;ALDH3A2;KMT5B;...
|
| Chagas disease |
-1.43 |
4.39e-1 |
93/102 (91.18%) |
IKBKG;AKT1;ADCY1;...
|
| FoxO signaling pathway |
-1.44 |
4.48e-1 |
118/131 (90.08%) |
AKT1;RBL2;CAT;...
|
| Cardiac muscle contraction |
-1.47 |
3.96e-1 |
64/87 (73.56%) |
COX6C;CACNB4;CACNB3;...
|
| Arginine and proline metabolism |
-1.49 |
3.86e-1 |
39/50 (78%) |
ALDH9A1;SMOX;CKM;...
|
| Citrate cycle (TCA cycle) |
-1.53 |
3.24e-1 |
30/30 (100%) |
IDH1;IDH3G;SDHA;...
|
| Glyoxylate and dicarboxylate metabolism |
-1.53 |
3.67e-1 |
23/30 (76.67%) |
SHMT2;CS;GLDC;...
|
| Rheumatoid arthritis |
-1.55 |
3.75e-1 |
78/93 (83.87%) |
CXCL5;ITGAL;CXCL3;...
|
| Glycerolipid metabolism |
-1.73 |
1.69e-1 |
44/61 (72.13%) |
ALDH9A1;LIPF;AKR1B1;...
|
| Starch and sucrose metabolism |
-1.84 |
6.32e-2 |
25/36 (69.44%) |
GCK;PGM1;GBA3;...
|
