Details of the Drug Pharmacogenomic Perturbation Atlas

General Information of Drug (ID: DMBP5N3)

Drug Name
Cantharidin Drug Info
Synonyms
DSSTox_CID_21752; DSSTox_RID_79835; DSSTox_GSID_41752; CAS-56-25-7; NCGC00016247-01; Spectrum_001114; SpecPlus_000537; Spectrum4_000920; Spectrum2_000630; Prestwick0_000885; Spectrum3_000621; Prestwick1_000885; Spectrum5_001618; Prestwick2_000885; KBioSS_001594; KBioGR_001420; BSPBio_002182; MLS002153505; SCHEMBL152261; DivK1c_006633; SPBio_002889; SPBio_000600; CHEMBL299846; DTXSID7041752; KBio2_006730; KBio3_001682; KBio2_004162; KBio2_001594; KBio1_001577; MolPort-003-665-556; HMS1570B12; Tox21_110326; CCG-39927; Tox21_110326_1
Cross-matching ID
PubChem CID
5944
ChEBI ID
CHEMBL48449
CAS Number
CAS 56-25-7
TTD Drug ID
D0Z2RA

Consensus Signature of Drug Pharmacogenomic Perturbation (DPP)
Term Name NES FDR q-val Tag % Leading Edge Genes
Steroid hormone biosynthesis -1.68 4.56e-2 43/61 (70.49%) UGT2B15;CYP11A1;AKR1C4;...
Antigen processing and presentation -1.72 3.32e-2 60/78 (76.92%) NFYC;PDIA3;TAP2;...
Autoimmune thyroid disease -1.74 3.21e-2 46/53 (86.79%) IL5;HLA-F;CD86;...
Viral protein interaction with cytokine and cytokine re... -1.76 2.74e-2 84/100 (84%) CCR6;CXCL5;IL18;...
beta-Alanine metabolism -1.80 2.28e-2 25/30 (83.33%) ACADS;GAD1;HADHA;...
Complement and coagulation cascades -1.86 1.71e-2 76/85 (89.41%) CR1;PLG;KNG1;...
Intestinal immune network for IgA production -1.87 1.47e-2 38/48 (79.17%) IL5;AICDA;CD86;...
Histidine metabolism -1.91 1.14e-2 16/22 (72.73%) ALDH9A1;ALDH3A2;ALDH2;...
Phagosome -1.92 1.37e-2 118/152 (77.63%) TAP2;HLA-F;C3;...
Valine, leucine and isoleucine degradation -1.94 8.55e-3 42/48 (87.5%) ACAT1;ACAD8;HIBCH;...
Ferroptosis -1.97 7.60e-3 36/41 (87.8%) GCLC;GCLM;PRNP;...
Tryptophan metabolism -2.02 5.70e-3 35/42 (83.33%) HADHA;DLD;AOX1;...
Mineral absorption -2.39 0.00e+0 48/60 (80%) VDR;CYBRD1;ATP1A1;...
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Pharmacogenomic Perturbation Across Diseases and Tissues

Prostate
Prostate carcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
VCaP CVCL_2235 Homo sapiens 0.37uM - 10uM 6H, 24H