| Complement and coagulation cascades |
1.80 |
9.20e-2 |
76/85 (89.41%) |
C1QA;C1QB;A2M;...
|
| Taurine and hypotaurine metabolism |
1.70 |
1.61e-1 |
8/11 (72.73%) |
CDO1;CSAD;BAAT;...
|
| Primary bile acid biosynthesis |
1.69 |
1.20e-1 |
15/17 (88.24%) |
AMACR;SLC27A5;SCP2;...
|
| Amoebiasis |
1.65 |
1.29e-1 |
99/102 (97.06%) |
COL4A5;COL4A2;CD14;...
|
| ABC transporters |
1.65 |
1.14e-1 |
37/45 (82.22%) |
ABCC3;ABCC10;ABCA2;...
|
| Dilated cardiomyopathy |
1.58 |
1.86e-1 |
86/96 (89.58%) |
TTN;ACTC1;DES;...
|
| Hypertrophic cardiomyopathy |
1.57 |
1.80e-1 |
81/90 (90%) |
TTN;ACTC1;DES;...
|
| Pertussis |
1.52 |
2.43e-1 |
64/76 (84.21%) |
C1QA;C1QB;SFTPA2;...
|
| Fatty acid biosynthesis |
1.49 |
2.69e-1 |
16/18 (88.89%) |
FASN;ACACA;ACSL1
|
| Cardiac muscle contraction |
1.47 |
2.84e-1 |
64/87 (73.56%) |
ACTC1;TNNC1;TPM3;...
|
| ECM-receptor interaction |
1.47 |
2.64e-1 |
80/88 (90.91%) |
SPP1;COL4A5;COL4A2;...
|
| Retinol metabolism |
1.42 |
3.43e-1 |
41/68 (60.29%) |
ALDH1A1;CYP2C8;CYP1A2;...
|
| Metabolism of xenobiotics by cytochrome P450 |
1.39 |
4.25e-1 |
49/77 (63.64%) |
GSTA4;GSTT1;GSTP1;...
|
| Bile secretion |
1.36 |
4.76e-1 |
68/90 (75.56%) |
SLC4A2;ABCC3;SLC27A5;...
|
| Steroid hormone biosynthesis |
1.35 |
4.72e-1 |
43/61 (70.49%) |
CYP1A2;HSD17B6;AKR1C1;...
|
| Histidine metabolism |
1.34 |
5.19e-1 |
16/22 (72.73%) |
ALDH3A1;ALDH3A2;HDC;...
|
| Ether lipid metabolism |
1.33 |
5.10e-1 |
32/49 (65.31%) |
LPCAT1;ENPP2;PLA2G2A;...
|
| Notch signaling pathway |
1.31 |
5.67e-1 |
49/59 (83.05%) |
RBPJ;NCOR2;KAT2A;...
|
| Hematopoietic cell lineage |
1.30 |
5.82e-1 |
90/99 (90.91%) |
CD14;CD55;FCER2;...
|
| Systemic lupus erythematosus |
1.30 |
5.54e-1 |
45/135 (33.33%) |
C1QA;C1QB;ACTN4;...
|
| GnRH secretion |
1.30 |
5.28e-1 |
60/64 (93.75%) |
SPP1;PLCB3;AKT1;...
|
| Sulfur metabolism |
1.28 |
5.53e-1 |
9/10 (90%) |
MPST;SELENBP1;ETHE1;...
|
| Vascular smooth muscle contraction |
1.27 |
5.52e-1 |
113/133 (84.96%) |
PLCB3;PLA2G2A;RAMP1;...
|
| Synaptic vesicle cycle |
1.26 |
5.80e-1 |
63/78 (80.77%) |
SLC1A3;NAPA;DNM1;...
|
| Linoleic acid metabolism |
1.24 |
6.26e-1 |
21/29 (72.41%) |
PLA2G2A;CYP2C8;CYP1A2;...
|
| Viral myocarditis |
1.24 |
6.21e-1 |
53/60 (88.33%) |
EIF4G1;ITGB2;ITGAL;...
|
| Drug metabolism |
1.23 |
6.06e-1 |
78/151 (51.66%) |
GSTA4;GSTT1;GSTP1;...
|
| Focal adhesion |
1.23 |
6.17e-1 |
180/201 (89.55%) |
SPP1;COL4A5;COL4A2;...
|
| Mannose type O-glycan biosynthesis |
1.18 |
6.67e-1 |
14/23 (60.87%) |
FUT9;B4GALT3;CHST10;...
|
| Ribosome biogenesis in eukaryotes |
1.18 |
6.50e-1 |
52/108 (48.15%) |
HEATR1;BMS1;DROSHA;...
|
| Lipid and atherosclerosis |
-1.27 |
5.34e-1 |
190/215 (88.37%) |
HSPA1L;PPP3CC;IKBKB;...
|
| Prostate cancer |
-1.27 |
5.42e-1 |
93/97 (95.88%) |
PTEN;PIK3CA;INS;...
|
| Pentose phosphate pathway |
-1.27 |
5.57e-1 |
25/30 (83.33%) |
RBKS;PRPS2;ALDOA;...
|
| RNA transport |
-1.29 |
5.14e-1 |
128/186 (68.82%) |
NCBP2;NUP54;NXT1;...
|
| Glycine, serine and threonine metabolism |
-1.29 |
5.23e-1 |
31/40 (77.5%) |
PSAT1;PIPOX;PSPH;...
|
| IL-17 signaling pathway |
-1.29 |
5.25e-1 |
84/94 (89.36%) |
S100A9;IKBKB;IFNG;...
|
| PD-L1 expression and PD-1 checkpoint pathway in cancer |
-1.30 |
5.26e-1 |
79/89 (88.76%) |
PIK3CB;PTEN;TLR4;...
|
| NF-kappa B signaling pathway |
-1.30 |
5.44e-1 |
90/104 (86.54%) |
IKBKB;DDX58;GADD45B;...
|
| Non-small cell lung cancer |
-1.30 |
5.46e-1 |
70/72 (97.22%) |
FHIT;GADD45B;PIK3CD;...
|
| Ovarian steroidogenesis |
-1.31 |
5.48e-1 |
41/51 (80.39%) |
ADCY3;BMP6;STAR;...
|
| Alcoholism |
-1.31 |
5.58e-1 |
86/186 (46.24%) |
GNG4;PKIA;GNAI2;...
|
| Hepatitis C |
-1.34 |
5.04e-1 |
139/157 (88.54%) |
MX1;CASP3;TLR3;...
|
| Glyoxylate and dicarboxylate metabolism |
-1.34 |
5.08e-1 |
23/30 (76.67%) |
MDH1;HAO2;ACAT1;...
|
| Propanoate metabolism |
-1.34 |
5.15e-1 |
30/34 (88.24%) |
ACAT1;ALDH6A1;ECHDC1;...
|
| p53 signaling pathway |
-1.35 |
5.25e-1 |
63/73 (86.3%) |
CHEK1;RCHY1;CASP3;...
|
| Glycosylphosphatidylinositol (GPI)-anchor biosynthesis |
-1.35 |
5.38e-1 |
20/26 (76.92%) |
PIGT;PIGA;PIGK;...
|
| Terpenoid backbone biosynthesis |
-1.36 |
5.43e-1 |
18/22 (81.82%) |
DHDDS;PCYOX1;FDPS;...
|
| MicroRNAs in cancer |
-1.37 |
5.53e-1 |
146/310 (47.1%) |
EFNA3;NOTCH3;CDC25A;...
|
| Ferroptosis |
-1.40 |
5.25e-1 |
36/41 (87.8%) |
PCBP2;HMOX1;FTH1;...
|
| Transcriptional misregulation in cancer |
-1.42 |
4.93e-1 |
158/192 (82.29%) |
DUSP6;BAK1;PBX1;...
|
| Amino sugar and nucleotide sugar metabolism |
-1.42 |
5.15e-1 |
38/48 (79.17%) |
FPGT;HK3;UAP1;...
|
| Steroid biosynthesis |
-1.46 |
4.28e-1 |
19/20 (95%) |
SQLE;NSDHL;CYP27B1;...
|
| Alanine, aspartate and glutamate metabolism |
-1.47 |
4.54e-1 |
27/37 (72.97%) |
ADSL;GOT1;GLUD1;...
|
| D-Glutamine and D-glutamate metabolism |
-1.47 |
4.88e-1 |
5/5 (100%) |
GLUD1;GLUD2
|
| Bladder cancer |
-1.49 |
4.62e-1 |
40/41 (97.56%) |
RB1;CDK4;E2F3;...
|
| TNF signaling pathway |
-1.49 |
5.24e-1 |
103/112 (91.96%) |
NOD2;BAG4;CASP3;...
|
| TGF-beta signaling pathway |
-1.61 |
3.44e-1 |
81/94 (86.17%) |
LTBP1;IFNG;SMURF2;...
|
| Signaling pathways regulating pluripotency of stem cell... |
-1.64 |
3.13e-1 |
110/143 (76.92%) |
HOXD1;SKIL;CTNNB1;...
|
| Mineral absorption |
-1.71 |
1.97e-1 |
48/60 (80%) |
SLC26A3;VDR;SLC5A1;...
|
| Proximal tubule bicarbonate reclamation |
-1.77 |
1.81e-1 |
21/23 (91.3%) |
ATP1B3;PCK1;SLC4A4;...
|
