Details of the Drug Pharmacogenomic Perturbation Atlas

General Information of Drug (ID: DMBVYDI)

Drug Name
Benzyl alcohol Drug Info
Synonyms Ulesfia (TN)
Cross-matching ID
PubChem CID
244
ChEBI ID
CHEMBL720
CAS Number
CAS 100-51-6
TTD Drug ID
D05OIS
INTEDE Drug ID
DR0200
ACDINA Drug ID
D00874

Consensus Signature of Drug Pharmacogenomic Perturbation (DPP)
Term Name NES FDR q-val Tag % Leading Edge Genes
Terpenoid backbone biosynthesis 2.08 2.15e-2 18/22 (81.82%) DHDDS;IDI1;HMGCS1;...
Steroid hormone biosynthesis 1.95 1.61e-2 43/61 (70.49%) CYP1B1;UGT2B28;AKR1C2;...
Steroid biosynthesis 1.83 3.58e-2 19/20 (95%) DHCR24;MSMO1;DHCR7;...
PPAR signaling pathway 1.81 3.22e-2 66/74 (89.19%) LPL;CD36;FADS2;...
Fatty acid biosynthesis 1.80 2.58e-2 16/18 (88.89%) ACSL1;ACSBG1;ACSL3;...
B cell receptor signaling pathway 1.74 4.29e-2 71/81 (87.65%) KRAS;LYN;SOS2;...
Focal adhesion -1.82 1.40e-2 180/201 (89.55%) ITGB7;TNXB;PAK2;...
ECM-receptor interaction -1.93 0.00e+0 80/88 (90.91%) DMP1;GP5;CHAD;...
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Pharmacogenomic Perturbation Across Diseases and Tissues

Breast epithelium
Normal
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
MCF-10A CVCL_0598 Homo sapiens 12uM - 100uM 48H
Liver
Hepatoblastoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
Hep G2 CVCL_0027 Homo sapiens 0.08uM - 100uM 3H, 24H, 48H
Lung
Lung adenocarcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
A549 CVCL_0023 Homo sapiens 0.08uM - 20uM 24H