Details of the Drug Pharmacogenomic Perturbation Atlas

General Information of Drug (ID: DMCAYXF)

• Drug Name: alpha-methyl-5-HT Drug Info
• Synonyms: alpha-Me-5-HT; alpha-methylserotonin
• Cross-matching ID:
  PubChem CID: 2107
  ChEBI ID: CHEMBL275854
  CAS Number: CAS 304-52-9
  TTD Drug ID: D09OYA

Consensus Signature of Drug Pharmacogenomic Perturbation (DPP)

Term Name	NES	FDR q-val	Tag %	Leading Edge Genes
Glutathione metabolism	1.95	1.77e-2	43/57 (75.44%)	ANPEP;GSTP1;GSTA1;...
Pertussis	1.92	1.48e-2	64/76 (84.21%)	PYCARD;SFTPA2;CALML5;...
Mineral absorption	-1.83	3.01e-2	48/60 (80%)	ATOX1;SLC31A1;ATP1B2;...
Long-term depression	-1.97	0.00e+0	55/60 (91.67%)	IGF1R;ITPR1;GNA12;...
Insulin secretion	-2.06	0.00e+0	75/86 (87.21%)	CREB3L2;SNAP25;CAMK2A;...

Pharmacogenomic Perturbation Across Diseases and Tissues

Fibroblast

Nasopharyngeal carcinoma

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
FIBRNPC	CVCL_UK07	Homo sapiens	10uM	6H, 24H	Hide ▲