Details of the Drug Pharmacogenomic Perturbation Atlas

General Information of Drug (ID: DMCKPG4)

• Drug Name: ABC294640 Drug Info
• Synonyms: ABC294640; 915385-81-8; Opaganib; ABC-294640; CHEMBL2158685; ABC 294640; UNII-DRG21OQ517; DRG21OQ517; Yeliva; SCHEMBL1548333; GTPL6624; CHEBI:124965; MolPort-044-560-286; HMS3402P05; BCP08959; EX-A1962; BDBM50393642; 3-(4-chlorophenyl)-N-(pyridin-4-ylmethyl)adamantane-1-carboxamide; AKOS027327311; CS-0877; SB17167; DB12764; API0017247; HY-16015; S7174; BRD-A70814879-003-01-8; ABC294640; 915385-81-8; ABC-294640
• Cross-matching ID:
  PubChem CID: 15604015
  ChEBI ID: CHEMBL2158685
  CAS Number: CAS 915385-81-8
  TTD Drug ID: D0X6BX

Consensus Signature of Drug Pharmacogenomic Perturbation (DPP)

Term Name	NES	FDR q-val	Tag %	Leading Edge Genes
DNA replication	2.21	0.00e+0	34/36 (94.44%)	FEN1;MCM3;MCM2;...
Staphylococcus aureus infection	1.85	4.54e-2	72/95 (75.79%)	C1QA;KRT14;KRT16;...
Mismatch repair	1.83	3.46e-2	22/23 (95.65%)	RFC3;PCNA;RFC4;...

Pharmacogenomic Perturbation Across Diseases and Tissues

Fibroblast

Nasopharyngeal carcinoma

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
FIBRNPC	CVCL_UK07	Homo sapiens	10uM	6H, 24H	Hide ▲