| Mineral absorption |
1.82 |
1.62e-1 |
48/60 (80%) |
CYBRD1;STEAP1;TF;...
|
| Vitamin digestion and absorption |
1.72 |
2.78e-1 |
17/24 (70.83%) |
APOB;APOA1;SLC5A6;...
|
| N-Glycan biosynthesis |
1.68 |
2.51e-1 |
38/50 (76%) |
ALG8;MGAT2;FUT8;...
|
| Terpenoid backbone biosynthesis |
1.68 |
1.88e-1 |
18/22 (81.82%) |
FNTA;ACAT2;PCYOX1;...
|
| Base excision repair |
1.67 |
1.55e-1 |
29/33 (87.88%) |
APEX1;FEN1;PCNA;...
|
| Nicotine addiction |
1.67 |
1.33e-1 |
32/40 (80%) |
GRIA2;GABRE;GABRP;...
|
| Drug metabolism |
1.64 |
1.47e-1 |
78/151 (51.66%) |
CYP3A5;CYP2E1;CES2;...
|
| Various types of N-glycan biosynthesis |
1.61 |
1.75e-1 |
26/39 (66.67%) |
MGAT2;FUT8;ALG13;...
|
| Arachidonic acid metabolism |
1.61 |
1.60e-1 |
48/61 (78.69%) |
GPX2;AKR1C3;CYP2E1;...
|
| Sulfur metabolism |
1.59 |
1.61e-1 |
9/10 (90%) |
ETHE1;TST;PAPSS1;...
|
| Gastric cancer |
1.59 |
1.48e-1 |
122/149 (81.88%) |
TGFBR2;LEF1;CDH17;...
|
| Homologous recombination |
1.58 |
1.58e-1 |
35/41 (85.37%) |
RPA1;PALB2;POLD4;...
|
| Hippo signaling pathway |
1.57 |
1.52e-1 |
120/186 (64.52%) |
TGFBR2;LEF1;PAK1;...
|
| Carbohydrate digestion and absorption |
1.54 |
1.89e-1 |
37/47 (78.72%) |
PLCB1;SLC2A5;ATP1A1;...
|
| Cholesterol metabolism |
1.54 |
1.80e-1 |
44/50 (88%) |
APOB;APOA1;VDAC1;...
|
| Aminoacyl-tRNA biosynthesis |
1.49 |
2.47e-1 |
15/66 (22.73%) |
NARS2;LARS2;FARSA;...
|
| Pentose phosphate pathway |
1.48 |
2.53e-1 |
25/30 (83.33%) |
ALDOB;PGD;TKTL1;...
|
| Biosynthesis of unsaturated fatty acids |
1.47 |
2.79e-1 |
21/27 (77.78%) |
ELOVL2;HACD2;SCD5;...
|
| Arrhythmogenic right ventricular cardiomyopathy |
1.46 |
2.77e-1 |
70/77 (90.91%) |
LEF1;CDH2;GJA1;...
|
| Thyroid hormone synthesis |
1.46 |
2.63e-1 |
66/75 (88%) |
PRKCA;PLCB1;GPX2;...
|
| Transcriptional misregulation in cancer |
1.45 |
2.68e-1 |
158/192 (82.29%) |
TGFBR2;DEFA5;HHEX;...
|
| Fat digestion and absorption |
1.44 |
2.86e-1 |
35/43 (81.4%) |
FABP1;APOB;APOA1;...
|
| Hepatocellular carcinoma |
1.43 |
2.90e-1 |
135/168 (80.36%) |
TGFBR2;LEF1;PRKCA;...
|
| Metabolism of xenobiotics by cytochrome P450 |
1.42 |
2.83e-1 |
49/77 (63.64%) |
CYP3A5;CYP2E1;UGT2B28;...
|
| Non-homologous end-joining |
1.41 |
2.95e-1 |
11/13 (84.62%) |
FEN1;PRKDC;MRE11;...
|
| Steroid hormone biosynthesis |
1.41 |
2.91e-1 |
43/61 (70.49%) |
CYP3A5;AKR1C3;CYP2E1;...
|
| Fatty acid elongation |
1.40 |
2.91e-1 |
19/27 (70.37%) |
ELOVL2;HACD2;ACAA2;...
|
| Bile secretion |
1.40 |
2.87e-1 |
68/90 (75.56%) |
ABCC3;ATP1A1;UGT2B28;...
|
| Porphyrin and chlorophyll metabolism |
1.40 |
2.78e-1 |
23/43 (53.49%) |
HEPH;UGT2B28;BLVRA;...
|
| Glycosaminoglycan degradation |
1.39 |
2.85e-1 |
19/19 (100%) |
HGSNAT;HEXB;GNS;...
|
| Staphylococcus aureus infection |
-1.25 |
4.78e-1 |
72/95 (75.79%) |
KRT17;DEFB4A;DSG1;...
|
| Tyrosine metabolism |
-1.25 |
4.77e-1 |
30/36 (83.33%) |
TH;TAT;AOC3;...
|
| C-type lectin receptor signaling pathway |
-1.26 |
4.81e-1 |
93/104 (89.42%) |
PLCG2;CLEC7A;PIK3R1;...
|
| Glycerolipid metabolism |
-1.26 |
4.79e-1 |
44/61 (72.13%) |
DGAT1;AGK;PLPP1;...
|
| Riboflavin metabolism |
-1.27 |
4.86e-1 |
7/8 (87.5%) |
ACP5;ENPP1
|
| Hedgehog signaling pathway |
-1.27 |
4.86e-1 |
43/56 (76.79%) |
EVC;HHAT;PTCH2;...
|
| Fluid shear stress and atherosclerosis |
-1.27 |
5.02e-1 |
123/139 (88.49%) |
SELE;ITGAV;PDGFA;...
|
| Viral protein interaction with cytokine and cytokine re... |
-1.29 |
4.73e-1 |
84/100 (84%) |
IL2RB;CXCR1;IL19;...
|
| Cytosolic DNA-sensing pathway |
-1.29 |
4.87e-1 |
52/63 (82.54%) |
POLR1D;POLR3B;POLR2E;...
|
| Regulation of lipolysis in adipocytes |
-1.31 |
4.65e-1 |
52/55 (94.55%) |
ADCY7;INSR;ADRB2;...
|
| Alcoholism |
-1.31 |
4.82e-1 |
86/186 (46.24%) |
CAMKK2;HDAC3;PKIA;...
|
| Pantothenate and CoA biosynthesis |
-1.33 |
4.57e-1 |
14/21 (66.67%) |
PANK3;PPCDC;ALDH2;...
|
| Longevity regulating pathway |
-1.33 |
4.74e-1 |
90/151 (59.6%) |
IGF1R;SOD2;PIK3R1;...
|
| Phototransduction |
-1.34 |
4.75e-1 |
21/29 (72.41%) |
CALML3;CALML5
|
| Steroid biosynthesis |
-1.37 |
3.98e-1 |
19/20 (95%) |
LSS;CYP27B1;TM7SF2;...
|
| Diabetic cardiomyopathy |
-1.40 |
3.49e-1 |
162/203 (79.8%) |
NDUFA5;GYS1;NDUFA6;...
|
| Non-alcoholic fatty liver disease |
-1.41 |
3.51e-1 |
126/155 (81.29%) |
IL1B;PPARG;DDIT3;...
|
| Malaria |
-1.42 |
3.48e-1 |
44/50 (88%) |
ITGAL;LRP1;CSF3;...
|
| Huntington disease |
-1.42 |
3.56e-1 |
233/306 (76.14%) |
POLR2L;ACTR10;RCOR1;...
|
| Thermogenesis |
-1.47 |
2.79e-1 |
173/232 (74.57%) |
NPR1;MLST8;ATP5F1A;...
|
| Parkinson disease |
-1.47 |
3.04e-1 |
176/249 (70.68%) |
ATP5F1A;MFN2;ATP5PF;...
|
| Mitophagy |
-1.48 |
3.05e-1 |
56/68 (82.35%) |
TBC1D17;MFN1;GABARAPL2;...
|
| Prion disease |
-1.48 |
3.27e-1 |
209/273 (76.56%) |
IL1B;ATP5PF;GRIN1;...
|
| Glycine, serine and threonine metabolism |
-1.48 |
3.68e-1 |
31/40 (77.5%) |
DLD;ALAS1;PGAM1;...
|
| IL-17 signaling pathway |
-1.51 |
3.41e-1 |
84/94 (89.36%) |
MAPK10;RELA;IL6;...
|
| Notch signaling pathway |
-1.51 |
3.78e-1 |
49/59 (83.05%) |
HEY1;DVL2;RBPJL;...
|
| RNA polymerase |
-1.52 |
4.35e-1 |
23/31 (74.19%) |
POLR1D;POLR2J;POLR3B;...
|
| Arginine and proline metabolism |
-1.58 |
4.39e-1 |
39/50 (78%) |
GOT1;OAT;LAP3;...
|
| Oxidative phosphorylation |
-1.86 |
6.67e-2 |
93/133 (69.92%) |
ATP6V1E1;ATP6V1H;TCIRG1;...
|
| Protein export |
-1.87 |
1.25e-1 |
17/23 (73.91%) |
SRP54;SRPRA;SRP72;...
|
