Details of the Drug Pharmacogenomic Perturbation Atlas

General Information of Drug (ID: DMDIC39)

• Drug Name: Fosfosal Drug Info
• Synonyms: Disdolen (TN)
• Cross-matching ID:
  PubChem CID: 3418
  ChEBI ID: CHEMBL287275
  CAS Number: CAS 6064-83-1
  TTD Drug ID: D0N3UL

Consensus Signature of Drug Pharmacogenomic Perturbation (DPP)

Term Name	NES	FDR q-val	Tag %	Leading Edge Genes
Ferroptosis	-1.89	3.30e-2	36/41 (87.8%)	GCLC;ACSL4;ATG5;...
Lysosome	-2.03	5.50e-3	115/128 (89.84%)	CTSF;LAMP2;ATP6V1H;...
Steroid biosynthesis	-2.32	0.00e+0	19/20 (95%)	DHCR7;SOAT1;HSD17B7;...

Pharmacogenomic Perturbation Across Diseases and Tissues

Breast

Breast adenocarcinoma

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
MCF7	CVCL_0031	Homo sapiens	10uM	6H, 24H	Hide ▲

Prostate

Prostate carcinoma

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
PC-3	CVCL_0035	Homo sapiens	1.11uM - 10uM	6H, 24H	Hide ▲

Skin

Melanoma

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
A-375	CVCL_0132	Homo sapiens	1.11uM - 10uM	24H	Show ▼