Details of the Drug Pharmacogenomic Perturbation Atlas

General Information of Drug (ID: DMDRKH2)

• Drug Name: Thiamphenicol Drug Info
• Synonyms: thiamphenicol; 15318-45-3; Thiophenicol; Thiamcol; (+)-Thiamphenicol; Raceophenidol; Dextrosulphenidol; Thiamphenicolum; D-Thiocymetin; D-Thiophenicol; Thiocymetin (TN); Armai (TN); Thiocymetin; Tiamfenicolo [DCIT]; UNII-FLQ7571NPM; Tiamfenicol [INN-Spanish]; Thiamphenicol (Thiophenicol); Macphenicol; C12H15Cl2NO5S; Urfamycine; Igralin; Hyrazin; Dexawin; Rincrol; Neomyson; Urfamicina; Thiamphenicolum [INN-Latin]; Descocin; Masatirin; Efnicol; SW 5063; Unaseran-D; Thiamphenicol [USAN:INN:BAN:JAN]; EINECS 239-355-3; RACEPHENICOL; WIN-5063-2
• Cross-matching ID:
  PubChem CID: 27200
  ChEBI ID: CHEMBL32215
  CAS Number: CAS 15318-45-3
  TTD Drug ID: D03YLZ
  VARIDT Drug ID: DR01326

Consensus Signature of Drug Pharmacogenomic Perturbation (DPP)

Term Name	NES	FDR q-val	Tag %	Leading Edge Genes
Synthesis and degradation of ketone bodies	1.94	3.94e-2	9/10 (90%)	ACAT2;HMGCS2;BDH2
Mineral absorption	-1.91	2.03e-2	48/60 (80%)	SLC26A3;MT1M;SLC11A2;...
Primary immunodeficiency	-1.96	2.03e-2	33/38 (86.84%)	CD4;IL2RG;CIITA;...

Pharmacogenomic Perturbation Across Diseases and Tissues

Breast

Breast adenocarcinoma

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
MCF7	CVCL_0031	Homo sapiens	10uM	6H, 24H	Hide ▲

Prostate

Prostate carcinoma

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
PC-3	CVCL_0035	Homo sapiens	10uM	24H	Hide ▲