Details of the Drug Pharmacogenomic Perturbation Atlas

General Information of Drug (ID: DME2A8X)

• Drug Name: 5-methoxypsoralen Drug Info
• Synonyms: 5-MOP
• Cross-matching ID:
  PubChem CID: 2355
  ChEBI ID: CHEMBL24171
  CAS Number: CAS 484-20-8
  TTD Drug ID: D0QR5G
  INTEDE Drug ID: DR1910

Consensus Signature of Drug Pharmacogenomic Perturbation (DPP)

Term Name	NES	FDR q-val	Tag %	Leading Edge Genes
Tryptophan metabolism	1.92	4.27e-2	35/42 (83.33%)	CYP1B1;TDO2;IDO1;...
Antigen processing and presentation	1.89	3.20e-2	60/78 (76.92%)	HSPA4;IFI30;IFNG;...
Ferroptosis	1.83	4.27e-2	36/41 (87.8%)	CP;SLC39A8;ACSL5;...
Mineral absorption	-1.91	1.82e-2	48/60 (80%)	CYBRD1;FXYD2;SLC31A1;...

Pharmacogenomic Perturbation Across Diseases and Tissues

Bone

Osteosarcoma

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
U-2 OS	CVCL_0042	Homo sapiens	10uM	6H	Hide ▲