Details of the Drug Pharmacogenomic Perturbation Atlas

General Information of Drug (ID: DMEH3O7)

Drug Name
Rifamycin Drug Info
Synonyms
Rifamycin SV; Rifamycin SV MMX; Rifamycin sodium; CB-01-11; Rifamycin (oral controlled-release, gastrointestinal-specific); Rifamycin (oral controlled-release, gastrointestinal-specific), Cosmo/Dr Falk/Santarus
Cross-matching ID
PubChem CID
6324616
ChEBI ID
CHEMBL437765
CAS Number
CAS 6998-60-3
TTD Drug ID
D0FX2Q
VARIDT Drug ID
DR00614
ACDINA Drug ID
D01389

Consensus Signature of Drug Pharmacogenomic Perturbation (DPP)
Term Name NES FDR q-val Tag % Leading Edge Genes
Primary immunodeficiency -1.66 3.57e-2 33/38 (86.84%) BLNK;CD19;PTPRC;...
NF-kappa B signaling pathway -1.67 3.53e-2 90/104 (86.54%) MYD88;TRAF5;LTBR;...
Asthma -1.69 3.16e-2 25/31 (80.65%) HLA-DMB;HLA-DRB1;HLA-DPB1;...
Influenza A -1.72 2.63e-2 156/172 (90.7%) DDX58;IFNAR2;IKBKG;...
Antigen processing and presentation -1.74 1.84e-2 60/78 (76.92%) NFYB;HSPA1A;TAP2;...
Systemic lupus erythematosus -1.75 1.65e-2 45/135 (33.33%) CD86;CD40LG;C1QB;...
Viral myocarditis -1.77 1.57e-2 53/60 (88.33%) CD86;CD40LG;RAC2;...
Lipid and atherosclerosis -1.77 1.48e-2 190/215 (88.37%) HSP90B1;FAS;NCF4;...
Leishmaniasis -1.79 1.46e-2 67/77 (87.01%) JAK2;STAT1;FCGR3B;...
Pertussis -1.82 5.71e-3 64/76 (84.21%) C1QB;C1S;C1R;...
Malaria -1.83 2.14e-3 44/50 (88%) CD81;HGF;THBS4;...
Intestinal immune network for IgA production -1.84 2.45e-3 38/48 (79.17%) TNFRSF13B;LTBR;CD86;...
Viral protein interaction with cytokine and cytokine re... -1.86 1.43e-3 84/100 (84%) CCL8;LTBR;CCR8;...
Toxoplasmosis -2.04 1.71e-3 103/112 (91.96%) CD40LG;BCL2;IL10RB;...
Phagosome -2.04 2.14e-3 118/152 (77.63%) TAP2;ATP6AP1;LAMP2;...
Legionellosis -2.06 2.86e-3 51/57 (89.47%) EEF1A2;CASP8;RAB1A;...
Mineral absorption -2.17 0.00e+0 48/60 (80%) CYBRD1;FTL;FXYD2;...
Rheumatoid arthritis -2.17 0.00e+0 78/93 (83.87%) ATP6AP1;MMP1;ATP6V1B2;...
×

Pharmacogenomic Perturbation Across Diseases and Tissues

Liver
Hepatocellular carcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
HuH-7 CVCL_0336 Homo sapiens 4uM 72H