Details of the Drug Pharmacogenomic Perturbation Atlas

General Information of Drug (ID: DMF0HWX)

• Drug Name: Hypoestoxide Drug Info
• Synonyms: 88498-46-8; hypoestoxide; (1R,3S,5S,8S,10S,12R,13S)-5,10,17,17-Tetramethyl-14-methylene-15-oxo-4,9-dioxatetracyclo[11.3.1.03,5.08,10]heptadecan-12-yl acetate; Hypoestoxide,hypoestes rosea; PD132594; [(1R,3S,5S,8S,10S,12R,13S)-5,10,17,17-tetramethyl-14-methylidene-15-oxo-4,9-dioxatetracyclo[11.3.1.03,5.08,10]heptadecan-12-yl] acetate
• Cross-matching ID:
  PubChem CID: 11199742
  TTD Drug ID: D5I9EV

Consensus Signature of Drug Pharmacogenomic Perturbation (DPP)

Term Name	NES	FDR q-val	Tag %	Leading Edge Genes
Spliceosome	1.99	9.73e-3	101/150 (67.33%)	HSPA8;HSPA1A;PUF60;...
African trypanosomiasis	1.76	4.14e-2	32/37 (86.49%)	PRKCB;IDO1;HBB;...

Pharmacogenomic Perturbation Across Diseases and Tissues

Prostate

Prostate carcinoma

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
PC-3	CVCL_0035	Homo sapiens	1.11uM - 10uM	24H	Hide ▲

Skin

Melanoma

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
A-375	CVCL_0132	Homo sapiens	1.11uM - 10uM	24H	Hide ▲