Details of the Drug Pharmacogenomic Perturbation Atlas

General Information of Drug (ID: DMFK8Y9)

Drug Name
Dehydrocholic acid Drug Info
Synonyms
Sodium dehydrocholate; 145-41-5; DEHYDROCHOLATE SODIUM; Dehydrocholate (sodium); Biliron; Carachol; Dehydrocholic acid sodium salt; UNII-W4193719XR; Suprachol; Biliton; Dycholium; Dilabil sodium; Decholin Sodium; Decholin sodium salt; W4193719XR; Natriumdehydrocholat [German]; Dehydrocholic acid, sodium salt; Sodium 3,7,12-triketocholanate; Natrii dehydrocholas [INN-Latin]; Dehidrocolato sodico [INN-Spanish]; EINECS 205-652-1; 81-23-2 (Parent); Dehydrocholate de sodium [INN-French]; Natriumdehydrocholat; Sodium 3,7,12-trioxo-5-bet
Cross-matching ID
PubChem CID
6674
ChEBI ID
CHEMBL31459
CAS Number
CAS 81-23-2
TTD Drug ID
D02ARR

Consensus Signature of Drug Pharmacogenomic Perturbation (DPP)
Term Name NES FDR q-val Tag % Leading Edge Genes
Legionellosis 2.18 0.00e+0 51/57 (89.47%) CD14;TLR4;ITGB2;...
Neutrophil extracellular trap formation 1.87 3.34e-2 101/189 (53.44%) PPIF;TLR4;FCGR2A;...
Mineral absorption -2.24 0.00e+0 48/60 (80%) ATP2B4;ATP1B3;ATOX1;...
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Pharmacogenomic Perturbation Across Diseases and Tissues

Breast
Breast adenocarcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
MCF7 CVCL_0031 Homo sapiens 10uM 6H, 24H
Colon
Colorectal adenocarcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
HT-29 CVCL_0320 Homo sapiens 10uM 6H
Kidney
Normal (Immortalized)
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
HA1E CVCL_0284 Homo sapiens 10uM 6H
Liver
Hepatoblastoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
Hep G2 CVCL_0027 Homo sapiens 10uM 6H
Lung
Lung adenocarcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
A549 CVCL_0023 Homo sapiens 10uM 6H, 24H
Non-small cell lung carcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
HCC515 CVCL_5134 Homo sapiens 10uM 6H
Prostate
Prostate carcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
PC-3 CVCL_0035 Homo sapiens 10uM 6H, 24H
VCaP CVCL_2235 Homo sapiens 10uM 6H, 24H
Skin
Melanoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
A-375 CVCL_0132 Homo sapiens 10uM 6H