| Complement and coagulation cascades |
1.94 |
5.26e-2 |
76/85 (89.41%) |
SERPINA1;CFI;CLU;...
|
| Cholesterol metabolism |
1.69 |
3.52e-1 |
44/50 (88%) |
PLTP;APOH;LIPG;...
|
| Chagas disease |
1.64 |
3.78e-1 |
93/102 (91.18%) |
GNAS;PLCB1;PPP2R1B;...
|
| Fatty acid biosynthesis |
1.59 |
4.52e-1 |
16/18 (88.89%) |
ACSL4;FASN;ACSL5;...
|
| Pyrimidine metabolism |
1.55 |
5.15e-1 |
40/56 (71.43%) |
CANT1;NT5E;DPYD;...
|
| Mineral absorption |
1.52 |
5.13e-1 |
48/60 (80%) |
MT1X;SLC34A2;MT1H;...
|
| Pentose phosphate pathway |
1.52 |
4.66e-1 |
25/30 (83.33%) |
PGD;PRPS2;FBP1;...
|
| Primary bile acid biosynthesis |
1.50 |
4.51e-1 |
15/17 (88.24%) |
AMACR;HSD17B4;CYP7A1;...
|
| Neomycin, kanamycin and gentamicin biosynthesis |
1.50 |
4.11e-1 |
5/5 (100%) |
HK2;HK1;HKDC1
|
| Allograft rejection |
1.49 |
4.23e-1 |
32/38 (84.21%) |
HLA-B;HLA-C;CD40;...
|
| Other glycan degradation |
1.46 |
4.51e-1 |
13/18 (72.22%) |
AGA;FUCA1;GLB1;...
|
| Mucin type O-glycan biosynthesis |
1.45 |
4.32e-1 |
20/36 (55.56%) |
B4GALT5;C1GALT1C1;C1GALT1;...
|
| Staphylococcus aureus infection |
1.45 |
3.99e-1 |
72/95 (75.79%) |
KRT17;CFI;KRT15;...
|
| Taurine and hypotaurine metabolism |
1.44 |
4.16e-1 |
8/11 (72.73%) |
GGT1;CDO1;ADO;...
|
| Cytokine-cytokine receptor interaction |
1.43 |
4.13e-1 |
246/295 (83.39%) |
CX3CL1;TNFSF10;CXCL10;...
|
| Sphingolipid metabolism |
1.42 |
4.28e-1 |
32/49 (65.31%) |
PLPP2;GLA;ARSA;...
|
| Small cell lung cancer |
1.41 |
4.16e-1 |
90/92 (97.83%) |
LAMC1;LAMA5;LAMC2;...
|
| alpha-Linolenic acid metabolism |
1.40 |
4.18e-1 |
17/25 (68%) |
PLAAT3;ACOX1;PLA2G4A;...
|
| Starch and sucrose metabolism |
1.40 |
4.13e-1 |
25/36 (69.44%) |
AGL;GBE1;GYS2;...
|
| Amoebiasis |
1.39 |
4.02e-1 |
99/102 (97.06%) |
LAMC1;GNAS;LAMA5;...
|
| Hippo signaling pathway |
1.39 |
4.01e-1 |
120/186 (64.52%) |
FZD5;WNT5A;PPP2R1B;...
|
| Selenocompound metabolism |
1.38 |
3.89e-1 |
11/17 (64.71%) |
PAPSS1;MTR;KYAT3;...
|
| Ferroptosis |
1.36 |
4.31e-1 |
36/41 (87.8%) |
CP;ACSL4;ACSL5;...
|
| Toxoplasmosis |
1.35 |
4.34e-1 |
103/112 (91.96%) |
LAMC1;LAMA5;LAMC2;...
|
| JAK-STAT signaling pathway |
1.33 |
4.88e-1 |
146/162 (90.12%) |
BCL2L1;PDGFA;IL15RA;...
|
| Linoleic acid metabolism |
1.32 |
4.97e-1 |
21/29 (72.41%) |
PLAAT3;PLA2G4A;CYP2C9;...
|
| Viral myocarditis |
1.32 |
4.80e-1 |
53/60 (88.33%) |
CXADR;DMD;HLA-B;...
|
| Autoimmune thyroid disease |
1.32 |
4.75e-1 |
46/53 (86.79%) |
HLA-B;TPO;HLA-C;...
|
| Endocrine and other factor-regulated calcium reabsorpti... |
1.30 |
5.21e-1 |
49/53 (92.45%) |
GNAS;PLCB1;ESR1;...
|
| Peroxisome |
1.29 |
5.15e-1 |
72/82 (87.8%) |
AMACR;ACSL4;PEX11A;...
|
| Amphetamine addiction |
-1.30 |
3.85e-1 |
57/69 (82.61%) |
SLC6A3;JUN;CAMK2A;...
|
| Proximal tubule bicarbonate reclamation |
-1.31 |
3.61e-1 |
21/23 (91.3%) |
ATP1A3;ATP1B2;MDH1;...
|
| Folate biosynthesis |
-1.32 |
3.69e-1 |
23/26 (88.46%) |
PTS;SPR;MOCOS;...
|
| Thyroid hormone signaling pathway |
-1.32 |
3.75e-1 |
112/121 (92.56%) |
PLCB2;NOTCH3;ATP1B1;...
|
| Retinol metabolism |
-1.33 |
3.77e-1 |
41/68 (60.29%) |
ALDH1A1;CYP1A2;DHRS3;...
|
| Dilated cardiomyopathy |
-1.34 |
3.60e-1 |
86/96 (89.58%) |
ITGB7;SGCA;ACTB;...
|
| Oocyte meiosis |
-1.34 |
3.58e-1 |
90/129 (69.77%) |
PKMYT1;PPP1CC;MAPK13;...
|
| Alcoholism |
-1.34 |
3.72e-1 |
86/186 (46.24%) |
NRAS;CALML5;MAPK3;...
|
| Glucagon signaling pathway |
-1.34 |
3.84e-1 |
89/107 (83.18%) |
PHKG1;PPARGC1A;GCG;...
|
| Aminoacyl-tRNA biosynthesis |
-1.36 |
3.74e-1 |
15/66 (22.73%) |
SARS2;DARS2;FARSA;...
|
| Tryptophan metabolism |
-1.37 |
3.60e-1 |
35/42 (83.33%) |
DHTKD1;CYP1A2;KYNU;...
|
| Long-term potentiation |
-1.37 |
3.63e-1 |
61/67 (91.04%) |
PPP1CC;PPP3CB;PPP1CA;...
|
| Vascular smooth muscle contraction |
-1.38 |
3.71e-1 |
113/133 (84.96%) |
PPP1CC;PPP1CA;PRKACB;...
|
| Terpenoid backbone biosynthesis |
-1.39 |
3.83e-1 |
18/22 (81.82%) |
DHDDS;PDSS1;IDI1;...
|
| Retrograde endocannabinoid signaling |
-1.40 |
3.77e-1 |
118/148 (79.73%) |
NDUFA6;KCNJ3;GABRB1;...
|
| Pyruvate metabolism |
-1.42 |
3.66e-1 |
41/47 (87.23%) |
MDH2;ACYP2;PCK2;...
|
| Huntington disease |
-1.47 |
2.65e-1 |
233/306 (76.14%) |
PSMA7;PSMD9;NDUFA6;...
|
| GABAergic synapse |
-1.48 |
2.62e-1 |
76/89 (85.39%) |
GABBR1;GPHN;PLCL1;...
|
| Alzheimer disease |
-1.49 |
2.60e-1 |
279/369 (75.61%) |
HSD17B10;ATP2A1;KRAS;...
|
| Thermogenesis |
-1.50 |
2.62e-1 |
173/232 (74.57%) |
NDUFB3;NDUFAF1;NDUFAF4;...
|
| Riboflavin metabolism |
-1.51 |
2.80e-1 |
7/8 (87.5%) |
BLVRB;ACP1;ENPP1
|
| Protein export |
-1.53 |
2.58e-1 |
17/23 (73.91%) |
SEC11A;SEC61G;SPCS1;...
|
| Cardiac muscle contraction |
-1.54 |
2.59e-1 |
64/87 (73.56%) |
ATP2A1;ATP1B2;COX7C;...
|
| Amyotrophic lateral sclerosis |
-1.59 |
2.18e-1 |
267/364 (73.35%) |
CCS;SETX;SDHB;...
|
| Diabetic cardiomyopathy |
-1.66 |
1.22e-1 |
162/203 (79.8%) |
NDUFS8;COX5B;NDUFAB1;...
|
| Non-alcoholic fatty liver disease |
-1.67 |
1.33e-1 |
126/155 (81.29%) |
PPARA;SDHB;IRS2;...
|
| Oxidative phosphorylation |
-1.68 |
1.35e-1 |
93/133 (69.92%) |
ATP6V0B;ATP5PO;COX7C;...
|
| Parkinson disease |
-1.69 |
1.67e-1 |
176/249 (70.68%) |
ATP5PO;COX7C;PSMA7;...
|
| B cell receptor signaling pathway |
-1.80 |
1.14e-1 |
71/81 (87.65%) |
LILRA1;NRAS;MAPK3;...
|
| Prion disease |
-1.82 |
1.89e-1 |
209/273 (76.56%) |
PSMD4;CAV2;NDUFB3;...
|
