| Insulin secretion |
1.84 |
9.58e-2 |
75/86 (87.21%) |
GNAS;RAB3A;RIMS2;...
|
| Long-term depression |
1.70 |
3.23e-1 |
55/60 (91.67%) |
GNAS;ITPR3;GRIA2;...
|
| Aldosterone synthesis and secretion |
1.69 |
2.20e-1 |
85/98 (86.73%) |
PDE2A;GNAS;ITPR3;...
|
| Cortisol synthesis and secretion |
1.62 |
2.88e-1 |
58/65 (89.23%) |
GNAS;ITPR3;KCNK3;...
|
| p53 signaling pathway |
1.53 |
4.31e-1 |
63/73 (86.3%) |
CDK1;CCNB1;SERPINB5;...
|
| Tyrosine metabolism |
1.52 |
4.26e-1 |
30/36 (83.33%) |
ADH1B;ALDH3A1;MAOA;...
|
| Ubiquinone and other terpenoid-quinone biosynthesis |
1.50 |
4.37e-1 |
9/11 (81.82%) |
NQO1
|
| Chronic myeloid leukemia |
1.49 |
4.11e-1 |
72/76 (94.74%) |
TGFBR2;CRK;CRKL;...
|
| Chagas disease |
1.49 |
3.70e-1 |
93/102 (91.18%) |
TGFBR2;CCL2;C1QA;...
|
| Oocyte meiosis |
1.42 |
4.97e-1 |
90/129 (69.77%) |
CDK1;CCNB1;SMC1A;...
|
| Serotonergic synapse |
1.41 |
4.86e-1 |
97/114 (85.09%) |
DUSP1;MAOA;GNAS;...
|
| Non-small cell lung cancer |
1.29 |
4.88e-1 |
70/72 (97.22%) |
ERBB2;PIK3CA;GADD45A;...
|
| Viral carcinogenesis |
1.29 |
4.89e-1 |
149/203 (73.4%) |
CDK1;GSN;C3;...
|
| Relaxin signaling pathway |
1.28 |
4.76e-1 |
114/129 (88.37%) |
TGFBR2;PIK3CA;GNAS;...
|
| MicroRNAs in cancer |
1.28 |
4.71e-1 |
146/310 (47.1%) |
SERPINB5;ERBB2;CD44;...
|
| Endocrine and other factor-regulated calcium reabsorpti... |
1.28 |
4.66e-1 |
49/53 (92.45%) |
GNAS;VDR;ATP1A1;...
|
| Phenylalanine metabolism |
1.27 |
4.75e-1 |
14/17 (82.35%) |
ALDH3A1;MAOA;GOT2;...
|
| Tight junction |
1.27 |
4.78e-1 |
130/169 (76.92%) |
ERBB2;RDX;PPP2R2B;...
|
| Dilated cardiomyopathy |
1.27 |
4.69e-1 |
86/96 (89.58%) |
ITGA6;GNAS;TNNC1;...
|
| Retinol metabolism |
1.27 |
4.59e-1 |
41/68 (60.29%) |
ADH1B;ALDH1A1;UGT2B15;...
|
| Central carbon metabolism in cancer |
1.27 |
4.51e-1 |
67/70 (95.71%) |
ERBB2;PKM;PIK3CA;...
|
| Chemical carcinogenesis |
1.26 |
4.46e-1 |
186/281 (66.19%) |
PIK3CA;CYP1B1;RPS6KA3;...
|
| cGMP-PKG signaling pathway |
1.26 |
4.39e-1 |
145/167 (86.83%) |
NFATC3;PDE2A;ITPR3;...
|
| Folate biosynthesis |
1.25 |
4.66e-1 |
23/26 (88.46%) |
AKR1B10;GGH;PTS;...
|
| Cholinergic synapse |
1.25 |
4.65e-1 |
99/113 (87.61%) |
PIK3CA;ITPR3;GNG12;...
|
| Glutamatergic synapse |
1.24 |
4.71e-1 |
97/114 (85.09%) |
GLS;SLC1A3;GNAS;...
|
| Prion disease |
1.24 |
4.78e-1 |
209/273 (76.56%) |
C1QA;NDUFV2;PIK3CA;...
|
| Gastric acid secretion |
1.24 |
4.76e-1 |
63/76 (82.89%) |
GNAS;ITPR3;ADCY2;...
|
| One carbon pool by folate |
1.23 |
4.79e-1 |
15/20 (75%) |
TYMS;SHMT2;MTHFD2;...
|
| Glycolysis / Gluconeogenesis |
1.23 |
4.70e-1 |
56/67 (83.58%) |
ADH1B;ALDH3A1;GPI;...
|
| Insulin signaling pathway |
-1.20 |
4.18e-1 |
121/137 (88.32%) |
PRKAR1A;TRIP10;SREBF1;...
|
| Non-alcoholic fatty liver disease |
-1.20 |
4.24e-1 |
126/155 (81.29%) |
MLXIP;PIK3CB;IL6;...
|
| Insulin resistance |
-1.20 |
4.28e-1 |
96/108 (88.89%) |
PPP1CB;TRIB3;PTPN1;...
|
| Amino sugar and nucleotide sugar metabolism |
-1.20 |
4.35e-1 |
38/48 (79.17%) |
UGDH;GNPDA1;HK2;...
|
| mTOR signaling pathway |
-1.22 |
4.36e-1 |
114/154 (74.03%) |
TSC2;FZD1;ATP6V1A;...
|
| Cholesterol metabolism |
-1.25 |
4.34e-1 |
44/50 (88%) |
LCAT;APOB;MYLIP;...
|
| PD-L1 expression and PD-1 checkpoint pathway in cancer |
-1.26 |
4.21e-1 |
79/89 (88.76%) |
TICAM1;MAP3K3;MYD88;...
|
| Propanoate metabolism |
-1.27 |
4.21e-1 |
30/34 (88.24%) |
MMUT;LDHB;ECHDC1;...
|
| NOD-like receptor signaling pathway |
-1.27 |
4.29e-1 |
145/181 (80.11%) |
NLRP3;BCL2L1;CXCL2;...
|
| Phagosome |
-1.27 |
4.34e-1 |
118/152 (77.63%) |
ATP6V1B1;ATP6V1F;RAB5B;...
|
| Valine, leucine and isoleucine degradation |
-1.28 |
4.36e-1 |
42/48 (87.5%) |
EHHADH;AUH;ALDH7A1;...
|
| Glycine, serine and threonine metabolism |
-1.36 |
3.94e-1 |
31/40 (77.5%) |
GLDC;GNMT;PIPOX;...
|
| Riboflavin metabolism |
-1.39 |
3.50e-1 |
7/8 (87.5%) |
FLAD1;ACP2;BLVRB;...
|
| Epithelial cell signaling in Helicobacter pylori infect... |
-1.39 |
3.68e-1 |
62/70 (88.57%) |
CASP3;PAK1;ADAM10;...
|
| Arginine and proline metabolism |
-1.41 |
3.39e-1 |
39/50 (78%) |
PYCR1;MAOB;ALDH7A1;...
|
| Graft-versus-host disease |
-1.42 |
3.43e-1 |
32/42 (76.19%) |
HLA-DPA1;HLA-E;PRF1;...
|
| TNF signaling pathway |
-1.45 |
2.94e-1 |
103/112 (91.96%) |
SOCS3;MAPK13;CREB1;...
|
| Alanine, aspartate and glutamate metabolism |
-1.45 |
3.02e-1 |
27/37 (72.97%) |
GLUL;ALDH4A1;ASS1;...
|
| Fatty acid elongation |
-1.46 |
3.12e-1 |
19/27 (70.37%) |
HACD3;HADHB;HADHA;...
|
| Protein processing in endoplasmic reticulum |
-1.48 |
2.93e-1 |
127/171 (74.27%) |
SEC31B;DNAJB12;HSP90B1;...
|
| Lysine degradation |
-1.48 |
3.20e-1 |
51/63 (80.95%) |
HADHA;SUV39H1;SMYD2;...
|
| Biosynthesis of unsaturated fatty acids |
-1.49 |
3.28e-1 |
21/27 (77.78%) |
HACD3;SCP2;HSD17B4;...
|
| Notch signaling pathway |
-1.51 |
3.15e-1 |
49/59 (83.05%) |
MFNG;DVL3;DTX4;...
|
| Other types of O-glycan biosynthesis |
-1.53 |
3.06e-1 |
29/47 (61.7%) |
OGT;GALNT3;GALNT14;...
|
| Nitrogen metabolism |
-1.58 |
2.27e-1 |
16/17 (94.12%) |
CA4;GLUL;CA14;...
|
| Primary immunodeficiency |
-1.63 |
1.76e-1 |
33/38 (86.84%) |
CD40;CD8B;LCK;...
|
| Fatty acid biosynthesis |
-1.65 |
1.85e-1 |
16/18 (88.89%) |
ACSBG2;ACACA;ACSL4;...
|
| Rheumatoid arthritis |
-1.74 |
1.02e-1 |
78/93 (83.87%) |
ATP6V1A;CXCL2;TCIRG1;...
|
| Taurine and hypotaurine metabolism |
-1.79 |
8.30e-2 |
8/11 (72.73%) |
GAD1;ADO;CSAD
|
| Collecting duct acid secretion |
-1.86 |
7.47e-2 |
22/27 (81.48%) |
ATP6V1B1;ATP6V1F;ATP6V1A;...
|
