| Nitrogen metabolism |
1.81 |
2.32e-1 |
16/17 (94.12%) |
CA12;CA2;CA3;...
|
| Steroid hormone biosynthesis |
1.77 |
1.61e-1 |
43/61 (70.49%) |
CYP3A5;DHRS11;CYP1B1;...
|
| Ascorbate and aldarate metabolism |
1.75 |
1.48e-1 |
15/30 (50%) |
ALDH3A2;UGT2A3;UGDH;...
|
| Glycerolipid metabolism |
1.73 |
1.39e-1 |
44/61 (72.13%) |
PLPP3;ALDH3A2;AKR1B10;...
|
| Pentose and glucuronate interconversions |
1.72 |
1.17e-1 |
17/34 (50%) |
AKR1B10;UGT2A3;UGDH;...
|
| PPAR signaling pathway |
1.65 |
1.87e-1 |
66/74 (89.19%) |
FABP7;ACSL1;HMGCS2;...
|
| Mitophagy |
1.65 |
1.61e-1 |
56/68 (82.35%) |
RRAS2;BCL2L1;KRAS;...
|
| Taurine and hypotaurine metabolism |
1.64 |
1.51e-1 |
8/11 (72.73%) |
GGT1;CDO1
|
| Fat digestion and absorption |
1.47 |
4.79e-1 |
35/43 (81.4%) |
PLPP3;PLA2G2A;ACAT2;...
|
| Hypertrophic cardiomyopathy |
1.47 |
4.42e-1 |
81/90 (90%) |
DES;TTN;ACTB;...
|
| Phosphonate and phosphinate metabolism |
1.42 |
5.62e-1 |
5/6 (83.33%) |
CHPT1;PCYT2
|
| Dilated cardiomyopathy |
1.39 |
6.01e-1 |
86/96 (89.58%) |
DES;TTN;ACTB;...
|
| Peroxisome |
1.38 |
5.91e-1 |
72/82 (87.8%) |
SOD2;ABCD3;ACSL1;...
|
| Ether lipid metabolism |
1.38 |
5.67e-1 |
32/49 (65.31%) |
PLPP3;PLA2G2A;CHPT1;...
|
| Mineral absorption |
1.37 |
5.50e-1 |
48/60 (80%) |
ATP2B4;MT1G;CYBRD1;...
|
| Maturity onset diabetes of the young |
1.36 |
5.47e-1 |
21/26 (80.77%) |
PAX6;HHEX;NEUROD1;...
|
| Autoimmune thyroid disease |
1.36 |
5.50e-1 |
46/53 (86.79%) |
PRF1;CGA;HLA-DMB;...
|
| Viral protein interaction with cytokine and cytokine re... |
1.34 |
5.93e-1 |
84/100 (84%) |
TNFSF10;CCL8;CX3CL1;...
|
| Allograft rejection |
1.34 |
5.74e-1 |
32/38 (84.21%) |
PRF1;HLA-DMB;TNF;...
|
| Cholesterol metabolism |
1.33 |
5.80e-1 |
44/50 (88%) |
PLTP;SORT1;VDAC1;...
|
| Bile secretion |
1.33 |
5.59e-1 |
68/90 (75.56%) |
CA2;SLC2A1;UGT2A3;...
|
| B cell receptor signaling pathway |
1.31 |
5.86e-1 |
71/81 (87.65%) |
NFATC3;BLNK;PIK3R1;...
|
| Vitamin digestion and absorption |
1.30 |
5.83e-1 |
17/24 (70.83%) |
SLC5A6;SLC19A2;APOB;...
|
| Central carbon metabolism in cancer |
1.29 |
5.81e-1 |
67/70 (95.71%) |
G6PD;FGFR3;PIK3R1;...
|
| Starch and sucrose metabolism |
1.27 |
6.00e-1 |
25/36 (69.44%) |
ENPP1;PYGB;PYGL;...
|
| Collecting duct acid secretion |
1.27 |
5.84e-1 |
22/27 (81.48%) |
ATP6V0E2;CA2;ATP6V1D;...
|
| Apoptosis |
1.26 |
6.01e-1 |
126/168 (75%) |
TNFSF10;ACTB;PRF1;...
|
| Amino sugar and nucleotide sugar metabolism |
1.25 |
5.99e-1 |
38/48 (79.17%) |
AMDHD2;CYB5R1;UGDH;...
|
| Fatty acid biosynthesis |
1.24 |
5.93e-1 |
16/18 (88.89%) |
ACSL1;FASN;ACSL4;...
|
| cAMP signaling pathway |
1.24 |
5.87e-1 |
188/216 (87.04%) |
SOX9;CALML5;GRIA2;...
|
| Growth hormone synthesis, secretion and action |
-1.17 |
6.11e-1 |
108/119 (90.76%) |
JUNB;PLCB2;SHC1;...
|
| D-Glutamine and D-glutamate metabolism |
-1.18 |
6.16e-1 |
5/5 (100%) |
GLS2;DGLUCY
|
| Melanogenesis |
-1.19 |
6.08e-1 |
74/101 (73.27%) |
KITLG;CREB3L1;POMC;...
|
| HIF-1 signaling pathway |
-1.19 |
6.20e-1 |
105/109 (96.33%) |
RPS6KB2;EIF4EBP1;EIF4E2;...
|
| Pancreatic cancer |
-1.19 |
6.23e-1 |
75/76 (98.68%) |
RELA;CDKN1A;TGFBR1;...
|
| Epithelial cell signaling in Helicobacter pylori infect... |
-1.20 |
6.11e-1 |
62/70 (88.57%) |
ATP6V1G1;RELA;ATP6V1H;...
|
| Amyotrophic lateral sclerosis |
-1.23 |
6.01e-1 |
267/364 (73.35%) |
CASP9;PIK3R4;RAE1;...
|
| Leishmaniasis |
-1.24 |
6.03e-1 |
67/77 (87.01%) |
CR1;FCGR3B;HLA-DPA1;...
|
| Kaposi sarcoma-associated herpesvirus infection |
-1.24 |
6.07e-1 |
172/193 (89.12%) |
RELA;CDKN1A;GNG10;...
|
| Endocrine and other factor-regulated calcium reabsorpti... |
-1.25 |
6.06e-1 |
49/53 (92.45%) |
ATP1B3;PLCB2;AP2M1;...
|
| Yersinia infection |
-1.25 |
6.04e-1 |
120/137 (87.59%) |
RELA;ARPC5L;ARPC1B;...
|
| Diabetic cardiomyopathy |
-1.27 |
5.66e-1 |
162/203 (79.8%) |
NDUFB8;TGFB2;NDUFA7;...
|
| Bladder cancer |
-1.28 |
5.61e-1 |
40/41 (97.56%) |
MMP1;TYMP;CDKN1A;...
|
| IL-17 signaling pathway |
-1.28 |
5.53e-1 |
84/94 (89.36%) |
MMP13;IL1B;MMP3;...
|
| Cell adhesion molecules |
-1.29 |
5.69e-1 |
118/148 (79.73%) |
CNTN2;CD6;ITGA6;...
|
| NOD-like receptor signaling pathway |
-1.29 |
5.85e-1 |
145/181 (80.11%) |
CARD8;BCL2;VDAC2;...
|
| Hematopoietic cell lineage |
-1.29 |
5.81e-1 |
90/99 (90.91%) |
CD7;ITGA6;CD37;...
|
| TGF-beta signaling pathway |
-1.31 |
5.38e-1 |
81/94 (86.17%) |
ACVR1;BMPR2;TGFBR1;...
|
| Rap1 signaling pathway |
-1.32 |
5.22e-1 |
184/210 (87.62%) |
MAP2K6;ADCY7;FGFR2;...
|
| Alzheimer disease |
-1.33 |
5.12e-1 |
279/369 (75.61%) |
APC;RTN3;NDUFA8;...
|
| Parkinson disease |
-1.33 |
5.22e-1 |
176/249 (70.68%) |
NDUFA8;COX7B;COX7A2L;...
|
| Caffeine metabolism |
-1.34 |
5.48e-1 |
5/6 (83.33%) |
NAT2;CYP2A6;NAT1
|
| Pathogenic Escherichia coli infection |
-1.34 |
5.71e-1 |
152/197 (77.16%) |
ACTR2;SEC24B;CLDN16;...
|
| Sphingolipid signaling pathway |
-1.35 |
5.65e-1 |
106/119 (89.08%) |
BCL2;SPTLC1;DEGS1;...
|
| Huntington disease |
-1.35 |
5.84e-1 |
233/306 (76.14%) |
CASP9;MAP2K7;PIK3R4;...
|
| Prostate cancer |
-1.36 |
5.81e-1 |
93/97 (95.88%) |
BCL2;RELA;CDKN1A;...
|
| Transcriptional misregulation in cancer |
-1.38 |
6.19e-1 |
158/192 (82.29%) |
PER2;HMGA2;IGFBP3;...
|
| Fatty acid elongation |
-1.57 |
4.95e-1 |
19/27 (70.37%) |
ACAA2;HSD17B12;HACD2;...
|
| Spliceosome |
-1.72 |
1.98e-1 |
101/150 (67.33%) |
SRSF10;SNRNP40;SF3B1;...
|
| Protein export |
-1.84 |
1.39e-1 |
17/23 (73.91%) |
SEC11A;SRP54;SRP14;...
|
