| Citrate cycle (TCA cycle) |
1.77 |
2.46e-1 |
30/30 (100%) |
DLD;DLAT;ACO2;...
|
| Glutathione metabolism |
1.77 |
1.36e-1 |
43/57 (75.44%) |
ANPEP;PGD;GCLC;...
|
| Staphylococcus aureus infection |
1.69 |
1.64e-1 |
72/95 (75.79%) |
KRT14;KRT17;C3;...
|
| Non-homologous end-joining |
1.67 |
1.59e-1 |
11/13 (84.62%) |
XRCC5;NHEJ1;PRKDC;...
|
| Hematopoietic cell lineage |
1.65 |
1.60e-1 |
90/99 (90.91%) |
CD59;ANPEP;CD9;...
|
| Metabolism of xenobiotics by cytochrome P450 |
1.64 |
1.56e-1 |
49/77 (63.64%) |
AKR1C1;CYP1B1;EPHX1;...
|
| Ether lipid metabolism |
1.60 |
1.84e-1 |
32/49 (65.31%) |
CHPT1;PLPP3;ENPP2;...
|
| Biosynthesis of unsaturated fatty acids |
1.59 |
1.78e-1 |
21/27 (77.78%) |
HACD2;HSD17B4;HACD3;...
|
| RNA polymerase |
1.58 |
1.70e-1 |
23/31 (74.19%) |
POLR3E;POLR2A;POLR2K;...
|
| Glyoxylate and dicarboxylate metabolism |
1.55 |
2.06e-1 |
23/30 (76.67%) |
GLUL;DLD;ACO2;...
|
| RNA transport |
1.55 |
1.91e-1 |
128/186 (68.82%) |
EIF1AY;EIF5B;EIF3A;...
|
| Phenylalanine metabolism |
1.55 |
1.75e-1 |
14/17 (82.35%) |
ALDH3A1;MAOA;AOC3;...
|
| Steroid hormone biosynthesis |
1.54 |
1.67e-1 |
43/61 (70.49%) |
AKR1C2;AKR1C1;AKR1C3;...
|
| Drug metabolism |
1.53 |
1.66e-1 |
78/151 (51.66%) |
IMPDH2;ALDH3A1;MAOA;...
|
| Ribosome biogenesis in eukaryotes |
1.53 |
1.67e-1 |
52/108 (48.15%) |
REXO2;HEATR1;IMP4;...
|
| Intestinal immune network for IgA production |
1.50 |
2.07e-1 |
38/48 (79.17%) |
HLA-DQA1;IL15;HLA-DRA;...
|
| Regulation of lipolysis in adipocytes |
1.49 |
1.98e-1 |
52/55 (94.55%) |
NPY1R;ADCY1;FABP4;...
|
| Pyruvate metabolism |
1.46 |
2.43e-1 |
41/47 (87.23%) |
DLD;DLAT;ME2;...
|
| Aldosterone-regulated sodium reabsorption |
1.46 |
2.39e-1 |
34/37 (91.89%) |
NR3C2;PIK3CA;IGF1;...
|
| Estrogen signaling pathway |
1.43 |
2.81e-1 |
119/137 (86.86%) |
KRT14;KRT17;KRT13;...
|
| Complement and coagulation cascades |
1.43 |
2.77e-1 |
76/85 (89.41%) |
CD59;C3;A2M;...
|
| Asthma |
1.43 |
2.65e-1 |
25/31 (80.65%) |
HLA-DQA1;HLA-DRA;HLA-DPB1;...
|
| Rheumatoid arthritis |
1.42 |
2.71e-1 |
78/93 (83.87%) |
CCL2;HLA-DQA1;ANGPT1;...
|
| Tryptophan metabolism |
1.40 |
2.98e-1 |
35/42 (83.33%) |
KYNU;CYP1B1;DLD;...
|
| Systemic lupus erythematosus |
1.39 |
2.97e-1 |
45/135 (33.33%) |
C3;C1R;C1S;...
|
| Viral myocarditis |
1.36 |
3.66e-1 |
53/60 (88.33%) |
CAV1;CXADR;HLA-DQA1;...
|
| Nitrogen metabolism |
1.35 |
3.78e-1 |
16/17 (94.12%) |
GLUL;GLUD2;GLUD1
|
| Folate biosynthesis |
1.34 |
3.85e-1 |
23/26 (88.46%) |
AKR1C3;AKR1B10;SPR;...
|
| Aminoacyl-tRNA biosynthesis |
1.33 |
3.93e-1 |
15/66 (22.73%) |
IARS2;FARSA;QRSL1;...
|
| PPAR signaling pathway |
1.33 |
3.88e-1 |
66/74 (89.19%) |
FABP5;FABP4;DBI;...
|
| Serotonergic synapse |
-1.19 |
5.49e-1 |
97/114 (85.09%) |
APP;HTR1B;GNB1;...
|
| Carbohydrate digestion and absorption |
-1.21 |
5.31e-1 |
37/47 (78.72%) |
ATP1B1;PLCB1;HK2;...
|
| Mineral absorption |
-1.21 |
5.42e-1 |
48/60 (80%) |
SLC5A1;ATOX1;ATP7B;...
|
| Cholinergic synapse |
-1.21 |
5.46e-1 |
99/113 (87.61%) |
FOS;GNB1;PLCB1;...
|
| Leukocyte transendothelial migration |
-1.22 |
5.36e-1 |
90/114 (78.95%) |
CYBB;PTPN11;ITGB2;...
|
| Pancreatic secretion |
-1.22 |
5.29e-1 |
87/102 (85.29%) |
ADCY9;SCT;ADCY7;...
|
| HIF-1 signaling pathway |
-1.23 |
5.27e-1 |
105/109 (96.33%) |
EPO;CREBBP;CUL2;...
|
| Cytokine-cytokine receptor interaction |
-1.23 |
5.31e-1 |
246/295 (83.39%) |
IL36RN;CXCR3;IFNGR2;...
|
| Inflammatory mediator regulation of TRP channels |
-1.23 |
5.37e-1 |
82/98 (83.67%) |
PLCB1;HRH1;MAP2K3;...
|
| Alanine, aspartate and glutamate metabolism |
-1.23 |
5.43e-1 |
27/37 (72.97%) |
AGXT;NIT2;GAD1;...
|
| Thyroid hormone synthesis |
-1.23 |
5.55e-1 |
66/75 (88%) |
ATF6B;ATP1B1;PLCB1;...
|
| GnRH signaling pathway |
-1.24 |
5.41e-1 |
80/93 (86.02%) |
PRKACB;CACNA1S;MAP3K2;...
|
| Cushing syndrome |
-1.25 |
5.25e-1 |
125/155 (80.65%) |
CYP11A1;ATF6B;PLCB1;...
|
| Human cytomegalovirus infection |
-1.26 |
5.03e-1 |
201/225 (89.33%) |
TAP1;PRKACB;GNG7;...
|
| Protein processing in endoplasmic reticulum |
-1.26 |
5.18e-1 |
127/171 (74.27%) |
HYOU1;DNAJC3;YOD1;...
|
| Glycosaminoglycan degradation |
-1.26 |
5.28e-1 |
19/19 (100%) |
HYAL4;HYAL3;IDS;...
|
| African trypanosomiasis |
-1.27 |
5.36e-1 |
32/37 (86.49%) |
PLCB3;TNF;PRKCA;...
|
| Starch and sucrose metabolism |
-1.27 |
5.40e-1 |
25/36 (69.44%) |
GYG1;ENPP1;MGAM
|
| Platelet activation |
-1.28 |
5.17e-1 |
106/124 (85.48%) |
SRC;PRKG1;ITGA2B;...
|
| Maturity onset diabetes of the young |
-1.30 |
4.87e-1 |
21/26 (80.77%) |
HNF4A;HES1;NKX6-1;...
|
| Relaxin signaling pathway |
-1.30 |
5.03e-1 |
114/129 (88.37%) |
SRC;FOS;GNB1;...
|
| Cell cycle |
-1.30 |
5.13e-1 |
110/124 (88.71%) |
ORC6;TGFB1;ATR;...
|
| Fc epsilon RI signaling pathway |
-1.30 |
5.31e-1 |
57/68 (83.82%) |
MAP2K3;IL13;PIK3CD;...
|
| Dopaminergic synapse |
-1.30 |
5.49e-1 |
115/132 (87.12%) |
FOS;GNB1;ATF6B;...
|
| Malaria |
-1.31 |
5.49e-1 |
44/50 (88%) |
TNF;SDC1;THBS1;...
|
| Gastric acid secretion |
-1.47 |
5.52e-1 |
63/76 (82.89%) |
ATP4A;KCNK10;ACTB;...
|
| Transcriptional misregulation in cancer |
-1.51 |
4.62e-1 |
158/192 (82.29%) |
BMI1;SPI1;BIRC2;...
|
| Hypertrophic cardiomyopathy |
-1.53 |
4.43e-1 |
81/90 (90%) |
ITGB4;CACNB4;SLC8A1;...
|
| Dilated cardiomyopathy |
-1.55 |
5.12e-1 |
86/96 (89.58%) |
ITGA1;TNNT2;ITGA2B;...
|
| Cortisol synthesis and secretion |
-1.61 |
3.85e-1 |
58/65 (89.23%) |
CYP11A1;ATF6B;PLCB1;...
|
