| Oxidative phosphorylation |
1.73 |
2.75e-1 |
93/133 (69.92%) |
NDUFA4L2;COX6B1;NDUFB2;...
|
| Carbohydrate digestion and absorption |
1.62 |
4.89e-1 |
37/47 (78.72%) |
MGAM;FXYD2;ATP1A1;...
|
| Prion disease |
1.57 |
5.38e-1 |
209/273 (76.56%) |
PRKCD;CAV2;NDUFA4L2;...
|
| Retinol metabolism |
1.53 |
5.70e-1 |
41/68 (60.29%) |
ALDH1A2;ALDH1A1;AOX1;...
|
| Thermogenesis |
1.51 |
5.30e-1 |
173/232 (74.57%) |
SMARCD2;NDUFA4L2;COX6B1;...
|
| Mucin type O-glycan biosynthesis |
1.48 |
5.39e-1 |
20/36 (55.56%) |
GALNT14;GALNT7;GALNT3;...
|
| Proteoglycans in cancer |
1.45 |
5.68e-1 |
172/205 (83.9%) |
FZD6;CAV2;ESR1;...
|
| Diabetic cardiomyopathy |
1.43 |
5.98e-1 |
162/203 (79.8%) |
PRKCD;NDUFA4L2;COX6B1;...
|
| Starch and sucrose metabolism |
1.40 |
6.63e-1 |
25/36 (69.44%) |
MGAM;AGL;HK2;...
|
| Parkinson disease |
1.40 |
6.05e-1 |
176/249 (70.68%) |
NDUFA4L2;COX6B1;MAOA;...
|
| Estrogen signaling pathway |
1.37 |
6.65e-1 |
119/137 (86.86%) |
KRT13;KRT19;PRKCD;...
|
| Ribosome |
1.32 |
6.81e-1 |
113/158 (71.52%) |
RPS4Y1;MRPS7;RPS26;...
|
| TGF-beta signaling pathway |
1.32 |
6.47e-1 |
81/94 (86.17%) |
RPS6KB1;ACVR1B;PITX2;...
|
| AMPK signaling pathway |
1.32 |
6.11e-1 |
106/120 (88.33%) |
PPP2R5E;FASN;RPS6KB1;...
|
| HIF-1 signaling pathway |
1.31 |
6.06e-1 |
105/109 (96.33%) |
TFRC;CYBB;RPS6KB1;...
|
| Proteasome |
1.20 |
6.81e-1 |
44/46 (95.65%) |
PSMC5;PSMD6;PSMD8;...
|
| Pyrimidine metabolism |
1.19 |
6.80e-1 |
40/56 (71.43%) |
ENTPD4;DPYS;NT5C;...
|
| Cholesterol metabolism |
1.19 |
6.78e-1 |
44/50 (88%) |
LRP2;ABCA1;APOB;...
|
| Amoebiasis |
1.19 |
6.70e-1 |
99/102 (97.06%) |
CTSG;SERPINB3;SERPINB4;...
|
| Fc epsilon RI signaling pathway |
1.19 |
6.54e-1 |
57/68 (83.82%) |
ALOX5AP;SOS1;GRB2;...
|
| Retrograde endocannabinoid signaling |
1.18 |
6.71e-1 |
118/148 (79.73%) |
GABRE;NDUFA4L2;GNG12;...
|
| IL-17 signaling pathway |
1.17 |
6.70e-1 |
84/94 (89.36%) |
S100A9;S100A8;CXCL1;...
|
| Sulfur metabolism |
1.16 |
6.80e-1 |
9/10 (90%) |
PAPSS2;ETHE1
|
| Type II diabetes mellitus |
1.16 |
6.69e-1 |
42/46 (91.3%) |
PRKCD;PKM;PIK3CA;...
|
| Non-alcoholic fatty liver disease |
1.15 |
6.71e-1 |
126/155 (81.29%) |
NDUFA4L2;COX6B1;NDUFB2;...
|
| Adrenergic signaling in cardiomyocytes |
1.15 |
6.80e-1 |
130/150 (86.67%) |
PPP2R5E;FXYD2;GNAQ;...
|
| Neutrophil extracellular trap formation |
1.14 |
6.80e-1 |
101/189 (53.44%) |
ELANE;CTSG;AZU1;...
|
| Other types of O-glycan biosynthesis |
1.12 |
6.77e-1 |
29/47 (61.7%) |
GALNT14;GALNT7;GALNT3;...
|
| Alcoholism |
1.12 |
6.74e-1 |
86/186 (46.24%) |
GNG12;MAOA;SOS1;...
|
| Aldosterone-regulated sodium reabsorption |
1.10 |
6.79e-1 |
34/37 (91.89%) |
SGK1;FXYD2;ATP1A1;...
|
| Ovarian steroidogenesis |
-1.28 |
3.58e-1 |
41/51 (80.39%) |
CYP11A1;AKR1C3;CYP19A1;...
|
| Arginine and proline metabolism |
-1.34 |
3.55e-1 |
39/50 (78%) |
SMS;CKB;ALDH3A2;...
|
| Wnt signaling pathway |
-1.34 |
3.56e-1 |
124/166 (74.7%) |
RAC2;RNF43;PPP3CC;...
|
| Th17 cell differentiation |
-1.34 |
3.65e-1 |
95/107 (88.79%) |
STAT5A;PPP3CC;IKBKB;...
|
| Antigen processing and presentation |
-1.36 |
3.29e-1 |
60/78 (76.92%) |
CTSS;HLA-E;NFYA;...
|
| Alanine, aspartate and glutamate metabolism |
-1.36 |
3.39e-1 |
27/37 (72.97%) |
GLUD2;GLS2;GFPT2;...
|
| Glutathione metabolism |
-1.38 |
3.07e-1 |
43/57 (75.44%) |
RRM1;GSTM5;GSTM3;...
|
| Natural killer cell mediated cytotoxicity |
-1.39 |
2.95e-1 |
99/131 (75.57%) |
IFNA21;KIR2DL3;PAK1;...
|
| Human cytomegalovirus infection |
-1.40 |
2.79e-1 |
201/225 (89.33%) |
RAC2;MDM2;IL10RB;...
|
| Selenocompound metabolism |
-1.41 |
2.80e-1 |
11/17 (64.71%) |
TXNRD3;KYAT1;SEPHS1;...
|
| Terpenoid backbone biosynthesis |
-1.42 |
2.70e-1 |
18/22 (81.82%) |
ACAT1;DHDDS;IDI1;...
|
| Steroid biosynthesis |
-1.43 |
2.59e-1 |
19/20 (95%) |
DHCR24;DHCR7;SOAT1;...
|
| Metabolism of xenobiotics by cytochrome P450 |
-1.44 |
2.53e-1 |
49/77 (63.64%) |
HSD11B1;UGT2B17;GSTP1;...
|
| Type I diabetes mellitus |
-1.46 |
2.28e-1 |
38/43 (88.37%) |
CD80;IL1A;HLA-DQB1;...
|
| One carbon pool by folate |
-1.48 |
2.14e-1 |
15/20 (75%) |
MTHFS;DHFR;AMT;...
|
| p53 signaling pathway |
-1.49 |
1.94e-1 |
63/73 (86.3%) |
GADD45B;ATM;BAX;...
|
| Human T-cell leukemia virus 1 infection |
-1.51 |
1.71e-1 |
197/219 (89.95%) |
NFATC3;MAPK8;FDPS;...
|
| Synthesis and degradation of ketone bodies |
-1.52 |
1.79e-1 |
9/10 (90%) |
HMGCL;HMGCS1;BDH2;...
|
| Cell adhesion molecules |
-1.53 |
1.68e-1 |
118/148 (79.73%) |
PDCD1LG2;F11R;MPZ;...
|
| Ascorbate and aldarate metabolism |
-1.55 |
1.53e-1 |
15/30 (50%) |
ALDH3A2;ALDH7A1;ALDH2;...
|
| Viral myocarditis |
-1.56 |
1.54e-1 |
53/60 (88.33%) |
HLA-E;MYH6;CASP8;...
|
| Cysteine and methionine metabolism |
-1.56 |
1.66e-1 |
43/50 (86%) |
SDS;LDHB;CBS;...
|
| Phagosome |
-1.56 |
1.80e-1 |
118/152 (77.63%) |
SEC61A1;C3;DYNC1LI2;...
|
| Protein export |
-1.56 |
1.93e-1 |
17/23 (73.91%) |
SEC61A1;SPCS1;SEC11A;...
|
| Autoimmune thyroid disease |
-1.57 |
2.10e-1 |
46/53 (86.79%) |
IFNA21;TG;TSHB;...
|
| alpha-Linolenic acid metabolism |
-1.57 |
2.23e-1 |
17/25 (68%) |
PLA2G12A;PLA2G2A;FADS2;...
|
| Kaposi sarcoma-associated herpesvirus infection |
-1.57 |
2.49e-1 |
172/193 (89.12%) |
HLA-E;CSF2;CCR3;...
|
| Butanoate metabolism |
-1.58 |
2.78e-1 |
23/28 (82.14%) |
HMGCS1;BDH2;ACSM3;...
|
| Viral carcinogenesis |
-1.58 |
3.19e-1 |
149/203 (73.4%) |
HDAC5;HDAC3;MDM2;...
|
| NF-kappa B signaling pathway |
-1.77 |
1.88e-1 |
90/104 (86.54%) |
IKBKB;ZAP70;TRAF5;...
|
