Details of the Drug Pharmacogenomic Perturbation Atlas

General Information of Drug (ID: DMGJSVD)

• Drug Name: P-Coumaric Acid Drug Info
• Synonyms: p-coumaric acid; 4-Hydroxycinnamic acid; p-Hydroxycinnamic acid; 501-98-4; 4-Coumaric acid; trans-4-Hydroxycinnamic acid; 7400-08-0; trans-p-Coumaric acid; p-Cumaric acid; 3-(4-hydroxyphenyl)acrylic acid; Para-Coumaric acid; Hydroxycinnamic acid; p-Hydroxy-cinnamic acid; Naringeninic acid; p-Hydroxyphenylacrylic acid; (E)-p-Coumaric acid; trans-p-Coumarinic acid; 4'-hydroxycinnamic acid; (E)-3-(4-Hydroxyphenyl)acrylic acid; Cinnamic acid, p-hydroxy-; (E)-p-Hydroxycinnamic acid; trans-p-Hydroxycinnamic acid
• Cross-matching ID:
  PubChem CID: 637542
  ChEBI ID: CHEMBL66879
  CAS Number: CAS 501-98-4
  TTD Drug ID: D0AU0M

Consensus Signature of Drug Pharmacogenomic Perturbation (DPP)

Term Name	NES	FDR q-val	Tag %	Leading Edge Genes
Retinol metabolism	2.14	0.00e+0	41/68 (60.29%)	ADH1B;CYP1A2;RETSAT;...
Linoleic acid metabolism	1.94	1.59e-2	21/29 (72.41%)	CYP1A2;PLAAT3;CYP2C9;...
Complement and coagulation cascades	1.90	2.13e-2	76/85 (89.41%)	THBD;SERPINB2;SERPING1;...
Steroid hormone biosynthesis	1.78	3.79e-2	43/61 (70.49%)	AKR1C3;AKR1C2;SRD5A1;...

Pharmacogenomic Perturbation Across Diseases and Tissues

Breast

Breast adenocarcinoma

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
MCF7	CVCL_0031	Homo sapiens	0.04uM - 10uM	24H	Hide ▲