| Retinol metabolism |
1.83 |
9.15e-2 |
41/68 (60.29%) |
AOX1;ADH1B;UGT2B15;...
|
| Fructose and mannose metabolism |
1.73 |
1.47e-1 |
30/33 (90.91%) |
TIGAR;AKR1B10;FBP1;...
|
| Fatty acid elongation |
1.72 |
1.13e-1 |
19/27 (70.37%) |
ACOT7;HADH;ELOVL2;...
|
| Metabolism of xenobiotics by cytochrome P450 |
1.71 |
9.31e-2 |
49/77 (63.64%) |
AKR1C1;GSTP1;ADH1B;...
|
| Arachidonic acid metabolism |
1.64 |
1.42e-1 |
48/61 (78.69%) |
GPX2;PLA2G2A;GPX3;...
|
| PPAR signaling pathway |
1.63 |
1.37e-1 |
66/74 (89.19%) |
FABP7;HMGCS2;FABP4;...
|
| Pentose and glucuronate interconversions |
1.61 |
1.33e-1 |
17/34 (50%) |
AKR1B10;UGT2B15;UGDH;...
|
| Ascorbate and aldarate metabolism |
1.55 |
1.97e-1 |
15/30 (50%) |
UGT2B15;UGDH;UGT2B17;...
|
| Drug metabolism |
1.55 |
1.82e-1 |
78/151 (51.66%) |
AOX1;UPP1;GSTP1;...
|
| Pyrimidine metabolism |
1.52 |
2.35e-1 |
40/56 (71.43%) |
UPP1;NT5C2;ENTPD6;...
|
| Collecting duct acid secretion |
1.51 |
2.30e-1 |
22/27 (81.48%) |
CA2;ATP6V1D;SLC12A7;...
|
| Taurine and hypotaurine metabolism |
1.50 |
2.25e-1 |
8/11 (72.73%) |
ADO;CSAD
|
| p53 signaling pathway |
1.49 |
2.24e-1 |
63/73 (86.3%) |
SERPINB5;BID;TP53I3;...
|
| Pentose phosphate pathway |
1.49 |
2.18e-1 |
25/30 (83.33%) |
FBP1;PFKP;RBKS;...
|
| Proximal tubule bicarbonate reclamation |
1.47 |
2.34e-1 |
21/23 (91.3%) |
CA2;SLC4A4;ATP1A2;...
|
| Ribosome biogenesis in eukaryotes |
1.45 |
2.70e-1 |
52/108 (48.15%) |
HEATR1;NXT1;NAT10;...
|
| Epithelial cell signaling in Helicobacter pylori infect... |
1.44 |
2.67e-1 |
62/70 (88.57%) |
JAM3;PAK1;CDC42;...
|
| Synaptic vesicle cycle |
1.39 |
3.54e-1 |
63/78 (80.77%) |
SNAP25;SLC1A1;SLC6A1;...
|
| Porphyrin and chlorophyll metabolism |
1.39 |
3.40e-1 |
23/43 (53.49%) |
CP;HEPH;UGT2B15;...
|
| Cell cycle |
1.39 |
3.31e-1 |
110/124 (88.71%) |
CDC25B;CDC20;PCNA;...
|
| Nitrogen metabolism |
1.37 |
3.45e-1 |
16/17 (94.12%) |
CA2;CA14;GLUD1;...
|
| D-Glutamine and D-glutamate metabolism |
1.37 |
3.40e-1 |
5/5 (100%) |
GLUD1;DGLUCY
|
| Oocyte meiosis |
1.35 |
3.78e-1 |
90/129 (69.77%) |
CDC20;ADCY9;PPP3R1;...
|
| Steroid hormone biosynthesis |
1.33 |
3.96e-1 |
43/61 (70.49%) |
AKR1C1;AKR1C3;HSD11B1;...
|
| Nicotinate and nicotinamide metabolism |
1.30 |
4.70e-1 |
25/35 (71.43%) |
AOX1;NT5C2;NNT;...
|
| Mucin type O-glycan biosynthesis |
1.28 |
5.25e-1 |
20/36 (55.56%) |
GCNT3;GALNT7;GALNT6;...
|
| Ether lipid metabolism |
1.25 |
5.79e-1 |
32/49 (65.31%) |
PLA2G2A;LPCAT1;ENPP2;...
|
| Glycerophospholipid metabolism |
1.25 |
5.60e-1 |
71/98 (72.45%) |
PLA2G2A;LPCAT1;CDS1;...
|
| Linoleic acid metabolism |
1.24 |
5.79e-1 |
21/29 (72.41%) |
PLA2G2A;CYP2J2;PLAAT3;...
|
| Fatty acid degradation |
1.24 |
5.76e-1 |
40/43 (93.02%) |
ADH1B;ACSL1;ADH1C;...
|
| Long-term depression |
-1.44 |
2.14e-1 |
55/60 (91.67%) |
PPP2R1B;PPP2CB;PLA2G4C;...
|
| ECM-receptor interaction |
-1.44 |
2.12e-1 |
80/88 (90.91%) |
THBS3;ITGB1;COL4A6;...
|
| Prolactin signaling pathway |
-1.46 |
2.01e-1 |
66/70 (94.29%) |
NRAS;SOCS5;SOCS2;...
|
| Dopaminergic synapse |
-1.46 |
2.04e-1 |
115/132 (87.12%) |
PPP2R1B;PPP1CB;FOS;...
|
| Epstein-Barr virus infection |
-1.48 |
1.94e-1 |
189/202 (93.56%) |
IFNB1;HLA-DMB;RELA;...
|
| Growth hormone synthesis, secretion and action |
-1.48 |
1.86e-1 |
108/119 (90.76%) |
STAT1;FOS;GRB2;...
|
| Neutrophil extracellular trap formation |
-1.49 |
1.85e-1 |
101/189 (53.44%) |
ATG7;SIGLEC9;VDAC1;...
|
| Gastric acid secretion |
-1.50 |
1.78e-1 |
63/76 (82.89%) |
ACTB;KCNJ16;GNAI1;...
|
| Antigen processing and presentation |
-1.51 |
1.70e-1 |
60/78 (76.92%) |
KLRC3;HSPA1L;B2M;...
|
| Regulation of lipolysis in adipocytes |
-1.53 |
1.64e-1 |
52/55 (94.55%) |
AKT2;ADCY1;PDE3B;...
|
| Cortisol synthesis and secretion |
-1.53 |
1.63e-1 |
58/65 (89.23%) |
CYP11B1;HSD3B1;CYP11A1;...
|
| Hepatitis C |
-1.53 |
1.68e-1 |
139/157 (88.54%) |
PPP2R1A;SOS1;SOCS3;...
|
| Amphetamine addiction |
-1.54 |
1.72e-1 |
57/69 (82.61%) |
FOSB;PPP1CB;FOS;...
|
| Influenza A |
-1.54 |
1.82e-1 |
156/172 (90.7%) |
SOCS3;CIITA;EIF2AK2;...
|
| Vibrio cholerae infection |
-1.55 |
1.76e-1 |
44/50 (88%) |
ACTB;ERO1A;KDELR1;...
|
| Amoebiasis |
-1.56 |
1.72e-1 |
99/102 (97.06%) |
RAB5C;CD1C;COL4A6;...
|
| Phospholipase D signaling pathway |
-1.56 |
1.84e-1 |
134/148 (90.54%) |
PLD2;NRAS;PIK3CG;...
|
| Aldosterone synthesis and secretion |
-1.62 |
1.16e-1 |
85/98 (86.73%) |
KCNJ5;NPPA;CYP11B2;...
|
| Alcoholism |
-1.62 |
1.18e-1 |
86/186 (46.24%) |
KRAS;SLC18A2;SLC29A2;...
|
| Necroptosis |
-1.62 |
1.28e-1 |
113/159 (71.07%) |
EIF2AK2;VDAC3;SHARPIN;...
|
| Relaxin signaling pathway |
-1.62 |
1.38e-1 |
114/129 (88.37%) |
SRC;ARRB1;SOS1;...
|
| Inflammatory bowel disease |
-1.63 |
1.43e-1 |
58/65 (89.23%) |
HLA-DOA;FOXP3;IL21;...
|
| Herpes simplex virus 1 infection |
-1.63 |
1.55e-1 |
165/498 (33.13%) |
IFNB1;PML;HLA-DMB;...
|
| Chagas disease |
-1.70 |
1.01e-1 |
93/102 (91.18%) |
TLR6;IFNB1;RELA;...
|
| Sulfur relay system |
-1.73 |
8.88e-2 |
5/8 (62.5%) |
MPST;NFS1;TST;...
|
| Measles |
-1.74 |
1.07e-1 |
133/139 (95.68%) |
IFNB1;IL2RA;RELA;...
|
| Cocaine addiction |
-1.80 |
7.06e-2 |
42/49 (85.71%) |
RELA;RGS9;CDK5R1;...
|
| Ovarian steroidogenesis |
-1.80 |
9.41e-2 |
41/51 (80.39%) |
INS;CYP1A1;BMP6;...
|
| Morphine addiction |
-1.81 |
1.18e-1 |
80/91 (87.91%) |
GABRB2;GNG5;GABRA3;...
|
| Parathyroid hormone synthesis, secretion and action |
-1.91 |
9.41e-2 |
98/106 (92.45%) |
ARRB1;CASR;SLC34A1;...
|
