Details of the Drug Pharmacogenomic Perturbation Atlas

General Information of Drug (ID: DMHM8ZK)

Drug Name
Propoxycaine Drug Info
Synonyms
Propoxycaine hydrochloride; Ravocaine hydrochloride; 550-83-4; Propoxycaine HCl; Propoxycaine (hydrochloride); Pravocaine hydrochloride; UNII-K490D39G46; WIN 3459; EINECS 208-988-7; Propoxycaine hydrochloride [USP]; K490D39G46; 2-(Diethylamino)ethyl 4-amino-2-propoxybenzoate monohydrochloride; 4-Amino-2-propoxybenzoic acid 2-(diethylamino)ethyl ester hydrochloride; Propoxycaine hydrochloride (USP); BENZOIC ACID, 4-AMINO-2-PROPOXY-, 2-(DIETHYLAMINO)ETHYL ESTER, MONOHYDROCHLORIDE; C16H26N2O3; NCGC00016505-01; CAS-550-83-4
Cross-matching ID
PubChem CID
6843
ChEBI ID
CHEMBL1195
CAS Number
CAS 86-43-1
TTD Drug ID
D0N6CR

Consensus Signature of Drug Pharmacogenomic Perturbation (DPP)
Term Name NES FDR q-val Tag % Leading Edge Genes
Mineral absorption -2.24 0.00e+0 48/60 (80%) ATP1A1;MT1HL1;HEPH;...
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Pharmacogenomic Perturbation Across Diseases and Tissues

Breast
Breast adenocarcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
MCF7 CVCL_0031 Homo sapiens 10uM 6H, 24H
Colon
Colorectal adenocarcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
HT-29 CVCL_0320 Homo sapiens 10uM 6H
Hematopoietic system
Normal
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
ASC CVCL_U602 Homo sapiens 10uM 24H
Kidney
Normal (Immortalized)
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
HA1E CVCL_0284 Homo sapiens 10uM 6H, 24H
Liver
Hepatoblastoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
Hep G2 CVCL_0027 Homo sapiens 10uM 6H
Lung
Lung adenocarcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
A549 CVCL_0023 Homo sapiens 10uM 6H, 24H
Non-small cell lung carcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
HCC515 CVCL_5134 Homo sapiens 10uM 6H, 24H
Prostate
Prostate carcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
PC-3 CVCL_0035 Homo sapiens 10uM 6H, 24H
VCaP CVCL_2235 Homo sapiens 10uM 6H, 24H
Skin
Melanoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
A-375 CVCL_0132 Homo sapiens 10uM 6H