Details of the Drug Pharmacogenomic Perturbation Atlas

General Information of Drug (ID: DMHN7CB)

Drug Name
Tributylstannanyl Drug Info
Synonyms
Tributyltin; tributylstannanyl; Tributlytin; Tributylstannic hydride; TRIBUTYL TIN; Tri-n-butylstannane hydride; UNII-4XDX163P3D; Tin, tri-n-butyl-, hydride; HSDB 6362; EINECS 211-704-4; BRN 3587329; 4XDX163P3D; Stannane, tri-n-butyl-, hydride; 20763-88-6; Tri-n-butyltin hydride, 97%; tri-n-butylstannyl radical; tributyl-tin; TBY; TBTH; AC1MHUMB; AC1Q2UP8; ACMC-1B91A; DTXSID0040709; CTK1A6693; MolPort-003-928-307; PIILXFBHQILWPS-UHFFFAOYSA-N; MolPort-035-869-643; EBD10558; ANW-35557; MFCD00009416; ZINC169748512; AKOS015909735
Cross-matching ID
PubChem CID
3032732
CAS Number
CAS 688-73-3
TTD Drug ID
D0CQ3A

Consensus Signature of Drug Pharmacogenomic Perturbation (DPP)
Term Name NES FDR q-val Tag % Leading Edge Genes
Glycine, serine and threonine metabolism 1.94 3.54e-2 31/40 (77.5%) MAOB;PGAM1;MAOA;...
Steroid biosynthesis -1.81 2.56e-2 19/20 (95%) LSS;LBR;HSD17B7;...
Protein export -1.84 2.13e-2 17/23 (73.91%) SRP54;SEC61A2;SRPRB;...
Thermogenesis -1.84 2.84e-2 173/232 (74.57%) NDUFAB1;ADCY7;COX6C;...
Vibrio cholerae infection -1.99 4.26e-3 44/50 (88%) PRKACA;ATP6V1F;TCIRG1;...
Oxidative phosphorylation -2.11 0.00e+0 93/133 (69.92%) ATP6V1C1;NDUFA8;COX17;...
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Pharmacogenomic Perturbation Across Diseases and Tissues

Breast
Breast adenocarcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
MCF7 CVCL_0031 Homo sapiens 10uM 6H
Kidney
Normal (Immortalized)
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
HA1E CVCL_0284 Homo sapiens 10uM 6H, 24H
Prostate
Prostate carcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
PC-3 CVCL_0035 Homo sapiens 10uM 6H