Details of the Drug Pharmacogenomic Perturbation Atlas

General Information of Drug (ID: DMI0G4Y)

Drug Name
Amorolfine Drug Info
Synonyms Loceryl; Pekiron; MT-861; Amorolfine (cream, onychomycosis); Ro-14-4767; Amorolfine (cream, onychomycosis), Roche; Ro-14-4767/002
Cross-matching ID
PubChem CID
54260
ChEBI ID
CHEMBL599440
CAS Number
CAS 78613-35-1
TTD Drug ID
D0QC3M

Consensus Signature of Drug Pharmacogenomic Perturbation (DPP)
Term Name NES FDR q-val Tag % Leading Edge Genes
Primary bile acid biosynthesis 2.03 0.00e+0 15/17 (88.24%) SLC27A5;HSD17B4;CH25H;...
Proteasome 1.91 1.52e-2 44/46 (95.65%) PSMB8;PSMB3;PSMB5;...
DNA replication -2.12 0.00e+0 34/36 (94.44%) RFC5;RFC2;MCM4;...
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Pharmacogenomic Perturbation Across Diseases and Tissues

Liver
Hepatocellular carcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
HuH-7 CVCL_0336 Homo sapiens 10uM 72H