| Estrogen signaling pathway |
2.01 |
1.28e-2 |
119/137 (86.86%) |
KRT14;HBEGF;TGFA;...
|
| Focal adhesion |
1.98 |
6.39e-3 |
180/201 (89.55%) |
ACTN1;ITGA6;JUN;...
|
| Salmonella infection |
1.97 |
4.26e-3 |
198/249 (79.52%) |
TUBB2A;JUN;PODXL;...
|
| Colorectal cancer |
1.88 |
3.20e-3 |
84/86 (97.67%) |
TGFA;JUN;AREG;...
|
| Renal cell carcinoma |
1.86 |
2.56e-3 |
68/69 (98.55%) |
TGFA;JUN;ETS1;...
|
| Hypertrophic cardiomyopathy |
1.85 |
2.13e-3 |
81/90 (90%) |
ITGA6;TPM1;ACTC1;...
|
| Chagas disease |
1.84 |
3.65e-3 |
93/102 (91.18%) |
JUN;PPP2CB;IRAK1;...
|
| Dilated cardiomyopathy |
1.83 |
6.39e-3 |
86/96 (89.58%) |
ITGA6;TPM1;ACTC1;...
|
| Hippo signaling pathway |
1.83 |
5.68e-3 |
120/186 (64.52%) |
AREG;PPP2CB;TP53BP2;...
|
| IL-17 signaling pathway |
1.81 |
7.67e-3 |
84/94 (89.36%) |
FOSL1;JUN;CXCL3;...
|
| Bladder cancer |
1.81 |
6.97e-3 |
40/41 (97.56%) |
HBEGF;MMP9;VEGFA;...
|
| Mineral absorption |
1.79 |
7.46e-3 |
48/60 (80%) |
MT1E;MT1H;MT1HL1;...
|
| Bacterial invasion of epithelial cells |
1.77 |
8.85e-3 |
59/77 (76.62%) |
CAV1;CLTB;ITGA5;...
|
| ErbB signaling pathway |
1.77 |
1.00e-2 |
79/85 (92.94%) |
HBEGF;TGFA;JUN;...
|
| TNF signaling pathway |
1.77 |
9.37e-3 |
103/112 (91.96%) |
JUN;CXCL3;MMP9;...
|
| MAPK signaling pathway |
1.77 |
8.79e-3 |
272/294 (92.52%) |
TGFA;RELB;JUN;...
|
| Proteoglycans in cancer |
1.68 |
2.78e-2 |
172/205 (83.9%) |
HBEGF;PLAUR;CAV1;...
|
| VEGF signaling pathway |
1.68 |
2.70e-2 |
50/59 (84.75%) |
SPHK1;VEGFA;AKT3;...
|
| Regulation of actin cytoskeleton |
1.68 |
2.62e-2 |
185/218 (84.86%) |
ACTN1;ITGA6;ITGA5;...
|
| FoxO signaling pathway |
1.68 |
2.49e-2 |
118/131 (90.08%) |
PLK2;PLK1;HOMER2;...
|
| Adherens junction |
1.67 |
2.80e-2 |
63/71 (88.73%) |
ACTN1;ACTN4;EGFR;...
|
| Arrhythmogenic right ventricular cardiomyopathy |
1.66 |
2.79e-2 |
70/77 (90.91%) |
ITGA6;ITGA5;ITGB4;...
|
| Apoptosis |
1.65 |
2.78e-2 |
126/168 (75%) |
JUN;CTSZ;CTSB;...
|
| Sphingolipid signaling pathway |
1.65 |
2.66e-2 |
106/119 (89.08%) |
PPP2CB;SPHK1;AKT3;...
|
| Epithelial cell signaling in Helicobacter pylori infect... |
1.65 |
2.61e-2 |
62/70 (88.57%) |
HBEGF;JUN;CXCL3;...
|
| Yersinia infection |
1.64 |
2.51e-2 |
120/137 (87.59%) |
JUN;IRAK1;ITGA5;...
|
| Regulation of lipolysis in adipocytes |
1.63 |
2.75e-2 |
52/55 (94.55%) |
MGLL;AKT3;FABP4;...
|
| Pathogenic Escherichia coli infection |
1.63 |
2.92e-2 |
152/197 (77.16%) |
TUBB2A;JUN;IRAK1;...
|
| Shigellosis |
1.62 |
2.91e-2 |
180/246 (73.17%) |
ACTN1;JUN;RIPK2;...
|
| MicroRNAs in cancer |
1.62 |
2.94e-2 |
146/310 (47.1%) |
TPM1;SLC7A1;TNC;...
|
| One carbon pool by folate |
-1.65 |
1.49e-2 |
15/20 (75%) |
MTHFD1;AMT;ALDH1L1;...
|
| Glycosylphosphatidylinositol (GPI)-anchor biosynthesis |
-1.65 |
1.47e-2 |
20/26 (76.92%) |
PIGV;PGAP1;PIGG;...
|
| Sulfur metabolism |
-1.68 |
1.17e-2 |
9/10 (90%) |
TST;SUOX;SELENBP1
|
| ABC transporters |
-1.69 |
1.14e-2 |
37/45 (82.22%) |
ABCC5;ABCG2;ABCB1;...
|
| Retinol metabolism |
-1.70 |
1.10e-2 |
41/68 (60.29%) |
DGAT1;CYP26B1;ADH1A;...
|
| beta-Alanine metabolism |
-1.76 |
5.71e-3 |
25/30 (83.33%) |
DPYD;ALDH9A1;HIBCH;...
|
| Glycolysis / Gluconeogenesis |
-1.78 |
4.17e-3 |
56/67 (83.58%) |
LDHB;ALDH9A1;PGK1;...
|
| Nucleotide excision repair |
-1.79 |
4.35e-3 |
40/47 (85.11%) |
RFC3;RFC2;POLD3;...
|
| Porphyrin and chlorophyll metabolism |
-1.85 |
9.74e-4 |
23/43 (53.49%) |
ALAD;COX15;GUSB;...
|
| Tryptophan metabolism |
-1.88 |
6.80e-4 |
35/42 (83.33%) |
ALDH2;KMO;GCDH;...
|
| Ascorbate and aldarate metabolism |
-1.89 |
3.57e-4 |
15/30 (50%) |
ALDH9A1;AKR1A1;ALDH2;...
|
| Valine, leucine and isoleucine degradation |
-1.90 |
3.76e-4 |
42/48 (87.5%) |
ACAT1;ALDH9A1;BCKDHB;...
|
| Tyrosine metabolism |
-1.92 |
3.97e-4 |
30/36 (83.33%) |
DCT;ADH1A;MAOA;...
|
| Citrate cycle (TCA cycle) |
-1.92 |
4.20e-4 |
30/30 (100%) |
PDHB;SDHD;PC;...
|
| Histidine metabolism |
-1.95 |
4.46e-4 |
16/22 (72.73%) |
HAL;ALDH9A1;MAOA;...
|
| Glyoxylate and dicarboxylate metabolism |
-1.96 |
0.00e+0 |
23/30 (76.67%) |
GRHPR;AMT;GLDC;...
|
| Folate biosynthesis |
-1.98 |
0.00e+0 |
23/26 (88.46%) |
ALPG;SPR;QDPR;...
|
| Peroxisome |
-2.00 |
0.00e+0 |
72/82 (87.8%) |
PEX12;HSD17B4;PAOX;...
|
| Mismatch repair |
-2.00 |
0.00e+0 |
22/23 (95.65%) |
RPA1;MLH1;MSH3;...
|
| Pyruvate metabolism |
-2.03 |
0.00e+0 |
41/47 (87.23%) |
LDHA;ME1;PKLR;...
|
| Oxidative phosphorylation |
-2.03 |
0.00e+0 |
93/133 (69.92%) |
NDUFA9;NDUFB4;NDUFB6;...
|
| Glutathione metabolism |
-2.04 |
0.00e+0 |
43/57 (75.44%) |
GGT1;GPX7;MGST2;...
|
| Fatty acid degradation |
-2.05 |
0.00e+0 |
40/43 (93.02%) |
ACAT1;ECI1;ALDH9A1;...
|
| Propanoate metabolism |
-2.05 |
0.00e+0 |
30/34 (88.24%) |
ACAT1;LDHB;BCKDHB;...
|
| Arachidonic acid metabolism |
-2.14 |
0.00e+0 |
48/61 (78.69%) |
PTGDS;PLA2G12A;ALOX15;...
|
| Pentose and glucuronate interconversions |
-2.23 |
0.00e+0 |
17/34 (50%) |
AKR1B1;GUSB;DCXR;...
|
| Steroid hormone biosynthesis |
-2.32 |
0.00e+0 |
43/61 (70.49%) |
HSD11B1;DHRS11;CYP21A2;...
|
| Drug metabolism |
-2.46 |
0.00e+0 |
78/151 (51.66%) |
FMO2;DPYD;NAT1;...
|
| DNA replication |
-2.53 |
0.00e+0 |
34/36 (94.44%) |
RFC3;RFC2;POLD3;...
|
| Metabolism of xenobiotics by cytochrome P450 |
-2.55 |
0.00e+0 |
49/77 (63.64%) |
HSD11B1;CBR1;ADH1A;...
|
