Details of the Drug Pharmacogenomic Perturbation Atlas

General Information of Drug (ID: DMINSOX)

• Drug Name: Pipamperone Drug Info
• Synonyms: Pipamperone; Floropipamide; Dipiperon; Dipiperone; 1893-33-0; Dipiperal; Piperonyl; Piperonil; Pipamperona; Pipamperonum; Pipamperone HCl; Pipaneperone; McN-JR-3345; R 3345; Pipamperonum [INN-Latin]; Pipamperona [INN-Spanish]; Propitan; pipamperone hydrochloride; Pipamperone [USAN:INN:BAN]; CCRIS 9071; UNII-5402501F0W; BRN 0496532; (1,4'-BIPIPERIDINE)-4'-CARBOXAMIDE, 1'-(3-(p-FLUOROBENZOYL)PROPYL)-; CHEBI:78549; p-Fluoro-gamma-(4-piperidino-4-carbamoylpiperidino)butyrophenone
• Cross-matching ID:
  PubChem CID: 4830
  ChEBI ID: CHEMBL78549
  CAS Number: CAS 1893-33-0
  TTD Drug ID: D00DBO

Consensus Signature of Drug Pharmacogenomic Perturbation (DPP)

Term Name	NES	FDR q-val	Tag %	Leading Edge Genes
Systemic lupus erythematosus	1.89	4.43e-2	45/135 (33.33%)	C1QA;C1QB;IFNG;...
Staphylococcus aureus infection	1.86	2.77e-2	72/95 (75.79%)	KRT13;KRT17;C1QA;...
Cell cycle	1.82	4.43e-2	110/124 (88.71%)	CCNE1;CCND2;SMC1A;...
Steroid biosynthesis	-2.14	0.00e+0	19/20 (95%)	SOAT1;TM7SF2;HSD17B7;...
Mineral absorption	-2.47	0.00e+0	48/60 (80%)	SLC39A4;ATP7A;CYBRD1;...

Pharmacogenomic Perturbation Across Diseases and Tissues

Breast

Breast adenocarcinoma

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
MCF7	CVCL_0031	Homo sapiens	10uM	6H, 24H	Hide ▲

Colon

Colorectal adenocarcinoma

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
HT-29	CVCL_0320	Homo sapiens	10uM	6H	Hide ▲

Hematopoietic system

Normal

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
ASC	CVCL_U602	Homo sapiens	10uM	24H	Show ▼

Kidney

Normal (Immortalized)

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
HA1E	CVCL_0284	Homo sapiens	10uM	6H, 24H	Show ▼

Liver

Hepatoblastoma

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
Hep G2	CVCL_0027	Homo sapiens	10uM	6H	Show ▼

Lung

Lung adenocarcinoma

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
A549	CVCL_0023	Homo sapiens	10uM	6H, 24H	Show ▼

Non-small cell lung carcinoma

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
HCC515	CVCL_5134	Homo sapiens	10uM	6H, 24H	Show ▼

Prostate

Prostate carcinoma

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
PC-3	CVCL_0035	Homo sapiens	10uM	6H, 24H	Show ▼
VCaP	CVCL_2235	Homo sapiens	10uM	6H, 24H	Show ▼

Skin

Melanoma

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
A-375	CVCL_0132	Homo sapiens	10uM	6H	Show ▼