General Information of Drug (ID: DMJFKG4)

Drug Name
acetaldehyde Drug Info
Synonyms acetic aldehyde; ethanal; ethyl aldehyde; NSC 7594
Cross-matching ID
PubChem CID
177
ChEBI ID
CHEMBL15343
CAS Number
CAS 75-07-0
TTD Drug ID
D0C7WN
INTEDE Drug ID
DR2007

Consensus Signature of Drug Pharmacogenomic Perturbation (DPP)

Term Name NES FDR q-val Tag % Leading Edge Genes
Cell cycle 2.04 0.00e+0 110/124 (88.71%) CCND2;CCNB1;SMC1A;...
Nucleotide excision repair 1.97 4.62e-3 40/47 (85.11%) RAD23B;RPA1;PCNA;...
Mismatch repair 1.92 1.23e-2 22/23 (95.65%) RPA1;PCNA;RFC5;...
IL-17 signaling pathway -1.64 4.65e-2 84/94 (89.36%) MAPK3;JUN;MAPK1;...
Herpes simplex virus 1 infection -1.64 4.38e-2 165/498 (33.13%) PIK3CB;TNF;HLA-DOB;...
Neomycin, kanamycin and gentamicin biosynthesis -1.65 4.38e-2 5/5 (100%) HK3;HK2
Amoebiasis -1.65 4.39e-2 99/102 (97.06%) TGFB3;PRKCA;LAMA4;...
Toxoplasmosis -1.66 4.50e-2 103/112 (91.96%) LAMA2;TNF;HLA-DOB;...
AGE-RAGE signaling pathway in diabetic complications -1.66 4.66e-2 97/100 (97%) PIK3CB;TNF;STAT5B;...
Type I diabetes mellitus -1.66 4.89e-2 38/43 (88.37%) HLA-C;CD86;IL1A;...
Influenza A -1.67 4.65e-2 156/172 (90.7%) PIK3CB;TNF;HLA-DOB;...
Th17 cell differentiation -1.67 4.68e-2 95/107 (88.79%) PRKCQ;HLA-DOB;PPP3CA;...
Cytosolic DNA-sensing pathway -1.68 4.70e-2 52/63 (82.54%) CHUK;RIPK1;MAVS;...
Rheumatoid arthritis -1.68 4.41e-2 78/93 (83.87%) ATP6V1A;CD80;IL6;...
C-type lectin receptor signaling pathway -1.69 4.56e-2 93/104 (89.42%) MAPK3;JUN;PLK3;...
Graft-versus-host disease -1.70 4.36e-2 32/42 (76.19%) CD80;IL6;HLA-C;...
TNF signaling pathway -1.71 3.88e-2 103/112 (91.96%) CX3CL1;CREB1;PIK3CB;...
Phagosome -1.74 2.98e-2 118/152 (77.63%) TUBB2A;TAP2;HLA-F;...
Osteoclast differentiation -1.74 3.16e-2 117/127 (92.13%) CREB1;PIK3CB;TNF;...
Malaria -1.75 3.37e-2 44/50 (88%) ACKR1;SDC1;TGFB3;...
NOD-like receptor signaling pathway -1.76 3.16e-2 145/181 (80.11%) TNF;MAP3K7;BIRC2;...
Asthma -1.78 2.37e-2 25/31 (80.65%) CD40;CD40LG;FCER1G;...
Tuberculosis -1.81 1.95e-2 159/180 (88.33%) MAPK13;IL10RA;IL6;...
Neutrophil extracellular trap formation -1.82 1.75e-2 101/189 (53.44%) PIK3CB;MAP3K7;PLCB2;...
ECM-receptor interaction -1.92 6.31e-3 80/88 (90.91%) COL1A1;GP1BA;ITGA5;...
Toll-like receptor signaling pathway -1.95 5.26e-3 94/104 (90.38%) PIK3CB;TNF;MAP3K7;...
Protein digestion and absorption -2.00 3.51e-3 78/103 (75.73%) COL13A1;SLC3A2;CTRL;...
Complement and coagulation cascades -2.00 5.26e-3 76/85 (89.41%) PROC;SERPINE1;C5;...
Leishmaniasis -2.07 1.05e-2 67/77 (87.01%) MAPK14;IL1A;NFKB1;...
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Pharmacogenomic Perturbation Across Diseases and Tissues

Breast
Breast adenocarcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
MCF7 CVCL_0031 Homo sapiens 20uM 6H
Kidney
Normal (Immortalized)
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
HA1E CVCL_0284 Homo sapiens 20uM 6H, 24H
Prostate
Prostate carcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
PC-3 CVCL_0035 Homo sapiens 20uM 6H, 24H