| Nicotine addiction |
1.70 |
2.36e-1 |
32/40 (80%) |
GRIA2;CACNA1A;GABRB1;...
|
| Nitrogen metabolism |
1.68 |
2.16e-1 |
16/17 (94.12%) |
GLUL;CA2;CA3;...
|
| Primary bile acid biosynthesis |
1.66 |
2.18e-1 |
15/17 (88.24%) |
CYP27A1;AKR1D1;CYP39A1;...
|
| Phenylalanine metabolism |
1.66 |
1.76e-1 |
14/17 (82.35%) |
PAH;MAOB;HPD;...
|
| Basal cell carcinoma |
1.65 |
1.51e-1 |
41/63 (65.08%) |
FZD7;TCF7;CTNNB1;...
|
| Cardiac muscle contraction |
1.64 |
1.42e-1 |
64/87 (73.56%) |
ATP1A2;TNNC1;MYL2;...
|
| Fluid shear stress and atherosclerosis |
1.56 |
2.37e-1 |
123/139 (88.49%) |
MEF2C;SRC;MGST2;...
|
| Vascular smooth muscle contraction |
1.51 |
3.26e-1 |
113/133 (84.96%) |
ITPR1;AGT;MYL6B;...
|
| Adherens junction |
1.51 |
2.96e-1 |
63/71 (88.73%) |
TGFBR2;SRC;TCF7;...
|
| Tyrosine metabolism |
1.50 |
2.97e-1 |
30/36 (83.33%) |
TYRP1;DCT;MAOB;...
|
| Phototransduction |
1.49 |
2.75e-1 |
21/29 (72.41%) |
CALML4;RGS9;CALML3;...
|
| Complement and coagulation cascades |
1.48 |
2.79e-1 |
76/85 (89.41%) |
SERPINA1;C3;A2M;...
|
| Other glycan degradation |
1.48 |
2.59e-1 |
13/18 (72.22%) |
HEXB;MAN2B2;NEU1;...
|
| Dilated cardiomyopathy |
1.46 |
2.77e-1 |
86/96 (89.58%) |
TTN;DES;TNNC1;...
|
| Retinol metabolism |
1.46 |
2.69e-1 |
41/68 (60.29%) |
DHRS3;ALDH1A1;RDH11;...
|
| Histidine metabolism |
1.45 |
2.67e-1 |
16/22 (72.73%) |
MAOB;ALDH9A1;HNMT;...
|
| Drug metabolism |
1.45 |
2.56e-1 |
78/151 (51.66%) |
MGST2;CES1;GSTT2;...
|
| Arrhythmogenic right ventricular cardiomyopathy |
1.44 |
2.58e-1 |
70/77 (90.91%) |
GJA1;DES;TCF7;...
|
| Valine, leucine and isoleucine degradation |
1.42 |
2.95e-1 |
42/48 (87.5%) |
ALDH6A1;ACAT2;ALDH9A1;...
|
| Oxidative phosphorylation |
1.40 |
3.14e-1 |
93/133 (69.92%) |
NDUFA7;COX4I1;NDUFB4;...
|
| Glyoxylate and dicarboxylate metabolism |
1.40 |
3.04e-1 |
23/30 (76.67%) |
GLUL;GLDC;ACAT2;...
|
| Fat digestion and absorption |
1.39 |
3.10e-1 |
35/43 (81.4%) |
PLPP3;ACAT2;PLA2G2A;...
|
| Hypertrophic cardiomyopathy |
1.38 |
3.24e-1 |
81/90 (90%) |
TTN;DES;TNNC1;...
|
| Adrenergic signaling in cardiomyocytes |
1.37 |
3.20e-1 |
130/150 (86.67%) |
ATP1A2;TNNC1;AGT;...
|
| Ribosome |
1.37 |
3.14e-1 |
113/158 (71.52%) |
MRPL22;RPL36AL;RPL26L1;...
|
| Bile secretion |
1.35 |
3.74e-1 |
68/90 (75.56%) |
ATP1A2;ADCY1;ABCB1;...
|
| Biosynthesis of unsaturated fatty acids |
1.34 |
3.62e-1 |
21/27 (77.78%) |
SCD5;HACD3;ELOVL2;...
|
| Antigen processing and presentation |
1.34 |
3.55e-1 |
60/78 (76.92%) |
CANX;HSPA8;HSPA5;...
|
| Linoleic acid metabolism |
1.34 |
3.59e-1 |
21/29 (72.41%) |
PLA2G2A;CYP2J2;PLA2G4C;...
|
| Cell adhesion molecules |
1.33 |
3.60e-1 |
118/148 (79.73%) |
CD99;CADM1;SELL;...
|
| Neurotrophin signaling pathway |
-1.37 |
2.66e-1 |
107/119 (89.92%) |
ARHGDIB;NFKBIB;CAMK2G;...
|
| Inflammatory bowel disease |
-1.38 |
2.70e-1 |
58/65 (89.23%) |
TBX21;RELA;IL4R;...
|
| mRNA surveillance pathway |
-1.38 |
2.75e-1 |
71/98 (72.45%) |
MSI1;NXT2;RNPS1;...
|
| Cytokine-cytokine receptor interaction |
-1.38 |
2.75e-1 |
246/295 (83.39%) |
IL22;IL36A;IL12RB2;...
|
| African trypanosomiasis |
-1.39 |
2.61e-1 |
32/37 (86.49%) |
IL10;PRKCG;GNAQ;...
|
| Galactose metabolism |
-1.41 |
2.46e-1 |
26/31 (83.87%) |
PFKM;PFKP;HK2;...
|
| AMPK signaling pathway |
-1.41 |
2.49e-1 |
106/120 (88.33%) |
PFKM;PIK3CD;CFTR;...
|
| AGE-RAGE signaling pathway in diabetic complications |
-1.41 |
2.52e-1 |
97/100 (97%) |
EGR1;PRKCZ;NOX4;...
|
| Chemokine signaling pathway |
-1.41 |
2.63e-1 |
163/192 (84.9%) |
PRKCZ;NFKBIB;CCR7;...
|
| Riboflavin metabolism |
-1.42 |
2.66e-1 |
7/8 (87.5%) |
BLVRB;ACP5;RFK
|
| Autophagy |
-1.42 |
2.74e-1 |
113/169 (66.86%) |
KRAS;DAPK1;AKT1;...
|
| Ribosome biogenesis in eukaryotes |
-1.43 |
2.64e-1 |
52/108 (48.15%) |
NOP10;REXO5;DROSHA;...
|
| Th1 and Th2 cell differentiation |
-1.45 |
2.40e-1 |
80/92 (86.96%) |
MAML3;DLL3;NFKBIB;...
|
| Other types of O-glycan biosynthesis |
-1.45 |
2.45e-1 |
29/47 (61.7%) |
C1GALT1;B4GALT3;GALNT14;...
|
| TGF-beta signaling pathway |
-1.47 |
2.35e-1 |
81/94 (86.17%) |
TGIF1;SMAD4;TGFBR1;...
|
| Hematopoietic cell lineage |
-1.49 |
2.05e-1 |
90/99 (90.91%) |
IL4R;CD7;IL2RA;...
|
| MicroRNAs in cancer |
-1.49 |
2.17e-1 |
146/310 (47.1%) |
E2F1;NFKB1;GRB2;...
|
| Amoebiasis |
-1.51 |
1.97e-1 |
99/102 (97.06%) |
NFKB1;LAMA3;IL1B;...
|
| Sphingolipid signaling pathway |
-1.51 |
2.11e-1 |
106/119 (89.08%) |
PRKCG;GNAQ;NSMAF;...
|
| Acute myeloid leukemia |
-1.51 |
2.25e-1 |
66/67 (98.51%) |
NFKB1;CEBPE;GRB2;...
|
| JAK-STAT signaling pathway |
-1.52 |
2.24e-1 |
146/162 (90.12%) |
JAK1;IL4R;IL22;...
|
| Phosphatidylinositol signaling system |
-1.53 |
2.29e-1 |
82/97 (84.54%) |
IP6K1;PLCB3;PIK3CD;...
|
| Sulfur metabolism |
-1.54 |
2.39e-1 |
9/10 (90%) |
PAPSS1;ETHE1;PAPSS2;...
|
| TNF signaling pathway |
-1.56 |
2.18e-1 |
103/112 (91.96%) |
VEGFD;TRAF2;IKBKB;...
|
| Regulation of lipolysis in adipocytes |
-1.57 |
2.43e-1 |
52/55 (94.55%) |
INS;PTGS2;ADCY9;...
|
| Hepatitis B |
-1.59 |
2.13e-1 |
151/162 (93.21%) |
JAK1;RELA;CCNE1;...
|
| Asthma |
-1.63 |
1.90e-1 |
25/31 (80.65%) |
FCER1G;IL10;MS4A2;...
|
| RIG-I-like receptor signaling pathway |
-1.63 |
2.15e-1 |
64/70 (91.43%) |
NFKBIB;RELA;MAPK9;...
|
| Inositol phosphate metabolism |
-1.64 |
2.62e-1 |
66/73 (90.41%) |
PLCB3;PIK3CD;INPPL1;...
|
| Mucin type O-glycan biosynthesis |
-1.72 |
1.58e-1 |
20/36 (55.56%) |
C1GALT1;ST3GAL2;ST6GALNAC4;...
|
