Details of the Drug Pharmacogenomic Perturbation Atlas

General Information of Drug (ID: DMJKHDL)

• Drug Name: Ioversol Drug Info
• Synonyms: ioversol; 87771-40-2; Optiray; Optiray 320; Ioversolum [Latin]; Optiray 240; Optiray 350; Optiray 160; MP-328; UNII-N3RIB7X24K; LOVERSOL; BRN 7155654; N3RIB7X24K; MP 328; 1,3-Benzenedicarboxamide, N,N'-bis(2,3-dihydroxypropyl)-5-((hydroxyacetyl)(2-hydroxyethyl)amino)-2,4,6-triiodo-; DSSTox_RID_80927; DSSTox_CID_25521; N,N'-Bis(2,3-dihydroxypropyl)-5-(N-(2-hydroxyethyl)glycolamido)-2,4,6-triiodoisophthalamide; DSSTox_GSID_45521; Optiray 300; Ioversolum
• Cross-matching ID:
  PubChem CID: 3741
  ChEBI ID: CHEMBL31717
  CAS Number: CAS 87771-40-2
  TTD Drug ID: D0U1ZD

Consensus Signature of Drug Pharmacogenomic Perturbation (DPP)

Term Name	NES	FDR q-val	Tag %	Leading Edge Genes
Mineral absorption	-1.90	1.77e-2	48/60 (80%)	MT2A;HMOX1;SLC5A1;...
Thyroid cancer	-1.94	2.83e-2	36/37 (97.3%)	NRAS;HRAS;TCF7L1;...

Pharmacogenomic Perturbation Across Diseases and Tissues

Breast

Breast adenocarcinoma

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
MCF7	CVCL_0031	Homo sapiens	10uM	6H, 24H	Hide ▲

Prostate

Prostate carcinoma

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
PC-3	CVCL_0035	Homo sapiens	10uM	6H, 24H	Hide ▲