Details of the Drug Pharmacogenomic Perturbation Atlas

General Information of Drug (ID: DMKB9FI)

• Drug Name: Benzoic Acid Drug Info
• Synonyms: Phenylformate; benzoate anion; Benzoic acid, ion(1-); 766-76-7; Benzeneformate; Tennplas; Phenylcarboxylate; Benzenemethanoate; Retarded BA; Benzenecarboxylate; Phenyl carboxylic acid; benzoic acid anion; Oracyclic acid; 4-Carboxybenzenide; Benzene formic acid; AC1Q1HDY; AC1Q22CA; AC1L18SS; GTPL4565; DTXSID4043771; CHEBI:16150; BDBM36181; CTK2H9612; WPYMKLBDIGXBTP-UHFFFAOYSA-M; STL483236; ZINC328578076; NCGC00247905-01; ZB000218; CJ-00025; LS-190261; 3230-EP2374454A1; 3230-EP2372017A1; 3230-EP2316825A1; 3230-EP2316457A1
• Cross-matching ID:
  PubChem CID: 243
  ChEBI ID: CHEMBL30746
  CAS Number: CAS 65-85-0
  TTD Drug ID: D0X9RY
  VARIDT Drug ID: DR00703

Consensus Signature of Drug Pharmacogenomic Perturbation (DPP)

Term Name	NES	FDR q-val	Tag %	Leading Edge Genes
Linoleic acid metabolism	-1.87	2.56e-2	21/29 (72.41%)	PLA2G5;CYP2C8;PLA2G2D;...
Ovarian steroidogenesis	-1.92	3.20e-2	41/51 (80.39%)	ADCY2;CGA;HSD17B7;...
Amino sugar and nucleotide sugar metabolism	-2.11	0.00e+0	38/48 (79.17%)	HK2;UGDH;CYB5R2;...

Pharmacogenomic Perturbation Across Diseases and Tissues

Breast

Breast adenocarcinoma

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
MCF7	CVCL_0031	Homo sapiens	20uM	6H	Hide ▲

Kidney

Normal (Immortalized)

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
HA1E	CVCL_0284	Homo sapiens	20uM	6H, 24H	Hide ▲

Prostate

Prostate carcinoma

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
PC-3	CVCL_0035	Homo sapiens	20uM	6H, 24H	Show ▼