Details of the Drug Pharmacogenomic Perturbation Atlas

General Information of Drug (ID: DMKCG8H)

• Drug Name: methyl salicylate Drug Info
• Synonyms: methyl salicylate; Methyl 2-hydroxybenzoate; 119-36-8; Wintergreen oil; Gaultheria oil; Betula oil; Teaberry oil; Sweet birch oil; OIL OF WINTERGREEN; Analgit; Spicewood Oil; Wintergruenoel; 2-Hydroxybenzoic acid methyl ester; Gaultheriaoel; Flucarmit; Exagien; Betula; Methyl o-hydroxybenzoate; 2-Carbomethoxyphenol; 2-(Methoxycarbonyl)phenol; Natural Wintergreen Oil; Betula Lenta; BIRCH-ME; Salicylic acid, methyl ester; Synthetic Wintergreen Oil; Benzoic acid, 2-hydroxy-, methyl ester; Gaultheria oil, artificial; Wintergreen Oil, syn
• Cross-matching ID:
  PubChem CID: 4133
  ChEBI ID: CHEMBL31832
  CAS Number: CAS 119-36-8
  TTD Drug ID: D0Z0AA

Consensus Signature of Drug Pharmacogenomic Perturbation (DPP)

Term Name	NES	FDR q-val	Tag %	Leading Edge Genes
Systemic lupus erythematosus	1.92	1.05e-2	45/135 (33.33%)	SNRPB;IFNG;C1S;...
Diabetic cardiomyopathy	-1.80	2.86e-2	162/203 (79.8%)	NDUFB4;RAC1;ATP2A1;...
Citrate cycle (TCA cycle)	-1.98	9.53e-3	30/30 (100%)	DLAT;IDH3G;PCK1;...
Oxidative phosphorylation	-2.09	0.00e+0	93/133 (69.92%)	COX7A2;ATP6V0A4;COX6A2;...

Pharmacogenomic Perturbation Across Diseases and Tissues

Liver

Hepatocellular carcinoma

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
HuH-7	CVCL_0336	Homo sapiens	20uM	72H	Hide ▲