Details of the Drug Pharmacogenomic Perturbation Atlas

General Information of Drug (ID: DMKSQUB)

Drug Name
DIDS Drug Info
Synonyms 4,4'-diisothiocyanostilbene-2,2'-disulphonic acid
Cross-matching ID
PubChem CID
5281951
ChEBI ID
CHEMBL1162148
CAS Number
CAS 152216-76-7
TTD Drug ID
D0PW7B

Consensus Signature of Drug Pharmacogenomic Perturbation (DPP)
Term Name NES FDR q-val Tag % Leading Edge Genes
DNA replication 1.98 8.68e-3 34/36 (94.44%) POLD4;RFC4;RNASEH1;...
Primary immunodeficiency 1.96 8.68e-3 33/38 (86.84%) CD19;ADA;CD79A;...
Tyrosine metabolism 1.91 8.68e-3 30/36 (83.33%) TYRP1;ADH1C;DDC;...
Taurine and hypotaurine metabolism -1.87 2.79e-2 8/11 (72.73%) ADO;GAD2;CSAD;...
Other glycan degradation -1.91 3.34e-2 13/18 (72.22%) HEXB;FUCA1;GLB1;...
Lysosome -1.94 4.46e-2 115/128 (89.84%) IDUA;CTSW;ARSA;...
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Pharmacogenomic Perturbation Across Diseases and Tissues

Breast
Breast adenocarcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
MCF7 CVCL_0031 Homo sapiens 10uM 6H, 24H
Colon
Colorectal adenocarcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
HT-29 CVCL_0320 Homo sapiens 10uM 6H
Hematopoietic system
Normal
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
ASC CVCL_U602 Homo sapiens 10uM 24H
Liver
Hepatoblastoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
Hep G2 CVCL_0027 Homo sapiens 10uM 6H
Lung
Lung adenocarcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
A549 CVCL_0023 Homo sapiens 10uM 6H, 24H
Skin
Melanoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
A-375 CVCL_0132 Homo sapiens 10uM 6H