Details of the Drug Pharmacogenomic Perturbation Atlas

General Information of Drug (ID: DMKV32D)

• Drug Name: Xylometazoline Drug Info
• Synonyms: Xylometazoline (nasal mucoadhesive/MucoAd, congestion); Decongestant (nasal mucoadhesive/MucoAd, congestion), Strategic BioSciences; Xylometazoline (nasal mucoadhesive/MucoAd, congestion), Strategic BioSciences
• Cross-matching ID:
  PubChem CID: 5709
  ChEBI ID: CHEMBL312448
  CAS Number: CAS 526-36-3
  TTD Drug ID: D0Y4DY

Consensus Signature of Drug Pharmacogenomic Perturbation (DPP)

Term Name	NES	FDR q-val	Tag %	Leading Edge Genes
Proteasome	1.84	4.13e-2	44/46 (95.65%)	PSMA3;PSMA6;PSMA2;...
Glycolysis / Gluconeogenesis	-2.02	0.00e+0	56/67 (83.58%)	ALDOA;PFKL;PKM;...

Pharmacogenomic Perturbation Across Diseases and Tissues

Bone

Osteosarcoma

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
U-2 OS	CVCL_0042	Homo sapiens	6.66uM	6H	Hide ▲

Breast

Breast adenocarcinoma

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
MCF7	CVCL_0031	Homo sapiens	10uM	6H, 24H	Hide ▲

Prostate

Prostate carcinoma

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
PC-3	CVCL_0035	Homo sapiens	10uM	24H	Show ▼