Details of the Drug Pharmacogenomic Perturbation Atlas

General Information of Drug (ID: DML6O4N)

• Drug Name: Dimethylformamide Drug Info
• Synonyms: N,N-DIMETHYLFORMAMIDE; Dimethylformamide; 68-12-2; N,N-Dimethylmethanamide; Dimethyl formamide; N-Formyldimethylamine; Formamide, N,N-dimethyl-; DMF; Dimethylformamid; Dimetilformamide; Dwumetyloformamid; DMFA; Formyldimethylamine; N,N-Dimethyl formamide; Dimethylforamide; Dimetylformamidu; DMF (amide); NCI-C60913; N,N-Dimethylformamid; n,n,dimethylformamide; Dimethylamid kyseliny mravenci; Caswell No. 366A; Dimetylformamidu [Czech]; Dimethylformamid [German]; Dimetilformamide [Italian]; Dwumetyloformamid [Polish]
• Cross-matching ID:
  PubChem CID: 6228
  ChEBI ID: CHEMBL17741
  CAS Number: CAS 68-12-2
  TTD Drug ID: D0E1KX
  INTEDE Drug ID: DR1120

Consensus Signature of Drug Pharmacogenomic Perturbation (DPP)

Term Name	NES	FDR q-val	Tag %	Leading Edge Genes
Steroid biosynthesis	1.95	0.00e+0	19/20 (95%)	SQLE;CYP51A1;DHCR7;...
alpha-Linolenic acid metabolism	1.87	2.63e-2	17/25 (68%)	FADS2;ACAA1;ACOX1;...
TNF signaling pathway	1.82	3.21e-2	103/112 (91.96%)	CCL20;JUNB;CEBPB;...
Pyruvate metabolism	-1.89	1.68e-2	41/47 (87.23%)	HAGH;ME2;ADH1C;...
Primary immunodeficiency	-1.89	3.36e-2	33/38 (86.84%)	AICDA;TAP1;ADA;...

Pharmacogenomic Perturbation Across Diseases and Tissues

Liver

Hepatoblastoma

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
Hep G2	CVCL_0027	Homo sapiens	1.25uM - 40uM	3H, 24H	Hide ▲