Details of the Drug Pharmacogenomic Perturbation Atlas

General Information of Drug (ID: DMLSABI)

• Drug Name: Hypoxanthine Drug Info
• Cross-matching ID:
  PubChem CID: 135398638
  ChEBI ID: CHEMBL17368
  CAS Number: CAS 68-94-0
  TTD Drug ID: D03HVE
  INTEDE Drug ID: DR0842

Consensus Signature of Drug Pharmacogenomic Perturbation (DPP)

Term Name	NES	FDR q-val	Tag %	Leading Edge Genes
Nicotinate and nicotinamide metabolism	-1.92	2.01e-2	25/35 (71.43%)	SIRT5;NT5C2;NNT;...

Pharmacogenomic Perturbation Across Diseases and Tissues

Breast

Fibrocystic breast disease

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
MCF-10A (Parent)	CVCL_0598	Homo sapiens	1.11uM - 10uM	3H, 6H, 12H, 24H	Hide ▲

Prostate

Prostate carcinoma

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
PC-3	CVCL_0035	Homo sapiens	1.11uM - 10uM	24H	Hide ▲

Skin

Melanoma

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
A-375	CVCL_0132	Homo sapiens	1.11uM - 10uM	24H	Show ▼