Details of the Drug Pharmacogenomic Perturbation Atlas

General Information of Drug (ID: DMLU8NX)

Drug Name
Benserazide Drug Info
Synonyms
benserazide; Serazide; 322-35-0; Benseraszide; Benserazida; Benserazidum; Ro 4-4602; Ro 44602; DL-Serine 2-(2,3,4-trihydroxybenzyl)hydrazide; Benserazidum [INN-Latin]; Benserazida [INN-Spanish]; Benserazide [USAN:INN:BAN]; DL-Seryltrihydroxybenzylhydrazine; C10H15N3O5; BRN 3984490; DL-Serine, 2-((2,3,4-trihydroxyphenyl)methyl)hydrazide; CHEBI:64187; DL-Serine 2-((2,3,4-trihydroxyphenyl)methyl)hydrazide; Serine, 2-(2,3,4-trihydroxybenzyl)hyrazide, DL-; DL-serine 2-[(2,3,4-trihydroxyphenyl)methyl]hydrazide
Cross-matching ID
PubChem CID
2327
ChEBI ID
CHEMBL64187
CAS Number
CAS 322-35-0
TTD Drug ID
D0X8ED

Consensus Signature of Drug Pharmacogenomic Perturbation (DPP)
Term Name NES FDR q-val Tag % Leading Edge Genes
PPAR signaling pathway 1.98 0.00e+0 66/74 (89.19%) LPL;CD36;ADIPOQ;...
Cholesterol metabolism 1.89 1.17e-2 44/50 (88%) LPL;CD36;APOB;...
Nucleotide excision repair 1.81 3.88e-2 40/47 (85.11%) PCNA;RFC2;RAD23A;...
DNA replication 1.81 3.79e-2 34/36 (94.44%) PCNA;RFC2;RFC5;...
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Pharmacogenomic Perturbation Across Diseases and Tissues

Breast
Breast adenocarcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
MCF7 CVCL_0031 Homo sapiens 10uM 6H, 24H
Liver
Hepatocellular carcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
HuH-7 CVCL_0336 Homo sapiens 12.5uM 72H
Prostate
Prostate carcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
PC-3 CVCL_0035 Homo sapiens 10uM 6H, 24H