Details of the Drug Pharmacogenomic Perturbation Atlas

General Information of Drug (ID: DMM3950)

Drug Name
Sodium chloride Drug Info
Synonyms
sodium chloride; 7647-14-5; Halite; Salt; Table salt; Saline; Rock salt; Common salt; Dendritis; Purex; Sodium chloric; Top flake; Sodium chloride (NaCl); Hyposaline; Flexivial; Gingivyl; Iodized salt; Slow Sodium; Sea salt; SS salt; Sodium monochloride; Natriumchlorid; Hypersal; Adsorbanac; Trisodium trichloride; White crystal; NaCl; HG blending; Salt (ingredient); sodiumchloride; Colyte; Sodium chloride (Na4Cl4); Caswell No 754; Extra Fine 325 Salt; Extra Fine 200 Salt; Sodium chloride brine, purified; Arm-A-Vial; CCRIS 982; sterling
Cross-matching ID
PubChem CID
5234
ChEBI ID
CHEMBL1200574
CAS Number
CAS 7647-14-5
TTD Drug ID
D04YZL
VARIDT Drug ID
DR01173

Consensus Signature of Drug Pharmacogenomic Perturbation (DPP)
Term Name NES FDR q-val Tag % Leading Edge Genes
Proteasome 2.33 0.00e+0 44/46 (95.65%) PSMD3;PSMB3;PSMA4;...
Allograft rejection 1.95 5.71e-3 32/38 (84.21%) HLA-DQB1;GZMB;PRF1;...
Autoimmune thyroid disease 1.92 1.90e-2 46/53 (86.79%) HLA-DQB1;GZMB;PRF1;...
Systemic lupus erythematosus 1.90 1.43e-2 45/135 (33.33%) SNRPB;HLA-DQB1;C1QA;...
Cell cycle 1.87 2.06e-2 110/124 (88.71%) PCNA;CDC25B;MCM2;...
Oocyte meiosis 1.86 1.71e-2 90/129 (69.77%) CDC20;SMC1A;SKP1;...
Viral myocarditis 1.75 4.24e-2 53/60 (88.33%) CD55;CASP3;HLA-DQB1;...
Antigen processing and presentation 1.74 4.28e-2 60/78 (76.92%) CTSB;IFI30;HLA-DQB1;...
Protein export -1.91 4.03e-2 17/23 (73.91%) SEC63;SPCS1;SEC11A;...
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Pharmacogenomic Perturbation Across Diseases and Tissues

Fibroblast
Nasopharyngeal carcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
FIBRNPC CVCL_UK07 Homo sapiens 0.12uM 6H, 24H