Details of the Drug Pharmacogenomic Perturbation Atlas

General Information of Drug (ID: DMMUH98)

Drug Name
9H-beta-Carboline-3-carboxylic acid propyl ester Drug Info
Synonyms
beta-Ccp; 76808-18-9; beta-Carboline-3-carboxylic acid propyl ester; propyl beta-carboline-3-carboxylate; Pbc-3-C; propyl 9H-pyrido[3,4-b]indole-3-carboxylate; 9H-Pyrido(3,4-b)indole-3-carboxylic acid, propyl ester; C15H14N2O2; Beta CCP; Biomol-NT_000275; AC1Q2Y9C; AC1L3X2D; AC1Q66NN; .beta.-Carboline-3-carboxylic acid propyl ester; SCHEMBL2348263; 9H-B-CARBOLINE-3-CARBOXYLIC ACID PROPYL ESTER; CHEMBL274847; BPBio1_001101; CTK5E3459; CHEBI:93491; BDBM84992; DTXSID30227627; WGRVAGIQTHEEQW-UHFFFAOYSA-N; ZINC2391117; PDSP2_001744
Cross-matching ID
PubChem CID
123662
ChEBI ID
CHEMBL1337028
CAS Number
CAS 76808-18-9
TTD Drug ID
D00OAN

Consensus Signature of Drug Pharmacogenomic Perturbation (DPP)
Term Name NES FDR q-val Tag % Leading Edge Genes
Mineral absorption 2.17 0.00e+0 48/60 (80%) MT1F;MT1H;MT2A;...
Primary immunodeficiency 2.02 0.00e+0 33/38 (86.84%) BLNK;CD8A;TAP1;...
Systemic lupus erythematosus 1.96 3.44e-3 45/135 (33.33%) FCGR3B;C1QB;ACTN4;...
Alcoholism -1.82 2.66e-2 86/186 (46.24%) GRB2;MAPK3;NRAS;...
Regulation of lipolysis in adipocytes -1.88 2.26e-2 52/55 (94.55%) ADRB2;PIK3CD;PRKG2;...
Citrate cycle (TCA cycle) -1.90 2.90e-2 30/30 (100%) PC;SDHB;SDHC;...
Steroid biosynthesis -2.13 9.67e-3 19/20 (95%) SOAT2;NSDHL;EBP;...
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Pharmacogenomic Perturbation Across Diseases and Tissues

Breast
Breast adenocarcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
MCF7 CVCL_0031 Homo sapiens 10uM 6H, 24H
Colon
Colorectal adenocarcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
HT-29 CVCL_0320 Homo sapiens 10uM 6H
Hematopoietic system
Normal
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
ASC CVCL_U602 Homo sapiens 10uM 24H
Kidney
Normal (Immortalized)
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
HA1E CVCL_0284 Homo sapiens 10uM 6H, 24H
Liver
Hepatoblastoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
Hep G2 CVCL_0027 Homo sapiens 10uM 6H
Lung
Lung adenocarcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
A549 CVCL_0023 Homo sapiens 10uM 6H, 24H
Non-small cell lung carcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
HCC515 CVCL_5134 Homo sapiens 10uM 6H, 24H
Prostate
Prostate carcinoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
PC-3 CVCL_0035 Homo sapiens 10uM 6H, 24H
VCaP CVCL_2235 Homo sapiens 10uM 6H, 24H
Skin
Melanoma
Cell Line Name Cellosaurus Accession Species of Origin Drug Dosage Time Point Details
A-375 CVCL_0132 Homo sapiens 10uM 6H