Details of the Drug Pharmacogenomic Perturbation Atlas

General Information of Drug (ID: DMN3E57)

• Drug Name: Levodopa Drug Info
• Synonyms: Levodopa (optimized formulation, Parkinson's disease); More effective levodopa (Parkinson's disease), Orion; Levodopa (optimized formulation, Parkinson's disease), Orion
• Cross-matching ID:
  PubChem CID: 6047
  ChEBI ID: CHEMBL1009
  CAS Number: CAS 59-92-7
  TTD Drug ID: D08HVR
  VARIDT Drug ID: DR00125
  INTEDE Drug ID: DR0939

Consensus Signature of Drug Pharmacogenomic Perturbation (DPP)

Term Name	NES	FDR q-val	Tag %	Leading Edge Genes
Aminoacyl-tRNA biosynthesis	1.89	1.65e-2	15/66 (22.73%)	GATC;IARS2;FARSA;...

Pharmacogenomic Perturbation Across Diseases and Tissues

Breast

Breast adenocarcinoma

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
MCF7	CVCL_0031	Homo sapiens	10uM	6H, 24H	Hide ▲

Liver

Hepatocellular carcinoma

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
HuH-7	CVCL_0336	Homo sapiens	15uM	72H	Hide ▲

Prostate

Prostate carcinoma

Cell Line Name	Cellosaurus Accession	Species of Origin	Drug Dosage	Time Point	Details
PC-3	CVCL_0035	Homo sapiens	10uM	24H	Show ▼